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Items: 1 to 20 of 53

1.

An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling.

Chiang KP, Niessen S, Saghatelian A, Cravatt BF.

Chem Biol. 2006 Oct;13(10):1041-50.

2.

Enzyme annotation with chemical tools.

Herman AG, Stockwell BR.

Chem Biol. 2006 Oct;13(10):1013-4.

3.

Synthesis and structure-activity relationship of (1-halo-2-naphthyl) carbamate-based inhibitors of KIAA1363 (NCEH1/AADACL1).

Shreder KR, Lin EC, Wu J, Cajica J, Amantea CM, Hu Y, Okerberg E, Brown HE, Pham LM, Chung de M, Fraser AS, McGee E, Rosenblum JS, Kozarich JW.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5748-51. doi: 10.1016/j.bmcl.2012.05.102. Epub 2012 Jun 6.

PMID:
22877630
4.

Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation.

Holly SP, Chang JW, Li W, Niessen S, Phillips RM, Piatt R, Black JL, Smith MC, Boulaftali Y, Weyrich AS, Bergmeier W, Cravatt BF, Parise LV.

Chem Biol. 2013 Sep 19;20(9):1125-34. doi: 10.1016/j.chembiol.2013.07.011. Epub 2013 Aug 29.

5.

Role of ether-linked lysophosphatidic acids in ovarian cancer cells.

Lu J, Xiao Yj YJ, Baudhuin LM, Hong G, Xu Y.

J Lipid Res. 2002 Mar;43(3):463-76.

6.

Dual roles of brain serine hydrolase KIAA1363 in ether lipid metabolism and organophosphate detoxification.

Nomura DK, Fujioka K, Issa RS, Ward AM, Cravatt BF, Casida JE.

Toxicol Appl Pharmacol. 2008 Apr 1;228(1):42-8. doi: 10.1016/j.taap.2007.11.021. Epub 2007 Dec 3.

7.

Annotating the unannotated.

Doerr A.

Nat Methods. 2007 Jan;4(1):8-9.

PMID:
17252630
8.

Organophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoids.

Casida JE, Nomura DK, Vose SC, Fujioka K.

Chem Biol Interact. 2008 Sep 25;175(1-3):355-64. doi: 10.1016/j.cbi.2008.04.008. Epub 2008 May 20. Review.

9.

Orphan enzymes in ether lipid metabolism.

Watschinger K, Werner ER.

Biochimie. 2013 Jan;95(1):59-65. doi: 10.1016/j.biochi.2012.06.027. Epub 2012 Jul 4. Review.

10.

A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis.

Chang JW, Nomura DK, Cravatt BF.

Chem Biol. 2011 Apr 22;18(4):476-84. doi: 10.1016/j.chembiol.2011.02.008.

11.

Ether lipids and platelet-activating factor: evolution and cellular function.

Kulikov VI, Muzya GI.

Biochemistry (Mosc). 1997 Oct;62(10):1103-8. Review.

PMID:
9461631
12.

Ether lipid synthesis and its deficiency in peroxisomal disorders.

van den Bosch H, Schrakamp G, Hardeman D, Zomer AW, Wanders RJ, Schutgens RB.

Biochimie. 1993;75(3-4):183-9. Review.

PMID:
8507680
13.

The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer.

Tanyi JL, Morris AJ, Wolf JK, Fang X, Hasegawa Y, Lapushin R, Auersperg N, Sigal YJ, Newman RA, Felix EA, Atkinson EN, Mills GB.

Cancer Res. 2003 Mar 1;63(5):1073-82.

14.

S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR).

Baudhuin LM, Jiang Y, Zaslavsky A, Ishii I, Chun J, Xu Y.

FASEB J. 2004 Feb;18(2):341-3. Epub 2003 Dec 4.

PMID:
14657000
15.

Chemical genetics screening reveals KIAA1363 as a cytokine-lowering target.

Hunerdosse DM, Morris PJ, Miyamoto DK, Fisher KJ, Bateman LA, Ghazaleh JR, Zhong S, Nomura DK.

ACS Chem Biol. 2014 Dec 19;9(12):2905-13. doi: 10.1021/cb500717g. Epub 2014 Nov 5.

16.

Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.

Harada T, Nakagawa Y, Wadkins RM, Potter PM, Wheelock CE.

Bioorg Med Chem. 2009 Jan 1;17(1):149-64. doi: 10.1016/j.bmc.2008.11.008. Epub 2008 Nov 9.

18.

Dietary lipid modification of renal disorders and ether phospholipid metabolism.

Holub BJ, Philbrick DJ, Parbtani A, Clark WF.

Biochem Cell Biol. 1991 Jul;69(7):485-9. Review.

PMID:
1793559
19.

Lysophosphatidic acid induces focal adhesion assembly through Rho/Rho-associated kinase pathway in human ovarian cancer cells.

Sawada K, Morishige Ki, Tahara M, Ikebuchi Y, Kawagishi R, Tasaka K, Murata Y.

Gynecol Oncol. 2002 Dec;87(3):252-9.

PMID:
12468322
20.

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