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Comparison of polymorphisms in genes involved in polycyclic aromatic hydrocarbon metabolism with urinary phenanthrene metabolite ratios in smokers.

Hecht SS, Carmella SG, Yoder A, Chen M, Li ZZ, Le C, Dayton R, Jensen J, Hatsukami DK.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1805-11.


Analysis of phenanthrols in human urine by gas chromatography-mass spectrometry: potential use in carcinogen metabolite phenotyping.

Carmella SG, Chen M, Yagi H, Jerina DM, Hecht SS.

Cancer Epidemiol Biomarkers Prev. 2004 Dec;13(12):2167-74.


Longitudinal study of urinary phenanthrene metabolite ratios: effect of smoking on the diol epoxide pathway.

Hecht SS, Chen M, Yoder A, Jensen J, Hatsukami D, Le C, Carmella SG.

Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):2969-74.


Phenanthrene metabolism in smokers: use of a two-step diagnostic plot approach to identify subjects with extensive metabolic activation.

Wang J, Zhong Y, Carmella SG, Hochalter JB, Rauch D, Oliver A, Jensen J, Hatsukami DK, Upadhyaya P, Hecht SS, Zimmerman CL.

J Pharmacol Exp Ther. 2012 Sep;342(3):750-60. doi: 10.1124/jpet.112.194118. Epub 2012 Jun 6.


Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race.

Nock NL, Tang D, Rundle A, Neslund-Dudas C, Savera AT, Bock CH, Monaghan KG, Koprowski A, Mitrache N, Yang JJ, Rybicki BA.

Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1236-45.


CYP1A1 and CYP1B1 polymorphisms and risk of lung cancer among never smokers: a population-based study.

Wenzlaff AS, Cote ML, Bock CH, Land SJ, Santer SK, Schwartz DR, Schwartz AG.

Carcinogenesis. 2005 Dec;26(12):2207-12. Epub 2005 Jul 28.


Metabolism of [D10]phenanthrene to tetraols in smokers for potential lung cancer susceptibility assessment: comparison of oral and inhalation routes of administration.

Zhong Y, Wang J, Carmella SG, Hochalter JB, Rauch D, Oliver A, Jensen J, Hatsukami DK, Upadhyaya P, Zimmerman C, Hecht SS.

J Pharmacol Exp Ther. 2011 Jul;338(1):353-61. doi: 10.1124/jpet.111.181719. Epub 2011 Apr 22.


Impact of metabolic genotypes on levels of biomarkers of genotoxic exposure.

Schoket B, Papp G, Lévay K, Mracková G, Kadlubar FF, Vincze I.

Mutat Res. 2001 Oct 1;482(1-2):57-69.


A urinary metabolite of phenanthrene as a biomarker of polycyclic aromatic hydrocarbon metabolic activation in workers exposed to residual oil fly ash.

Kim JY, Hecht SS, Mukherjee S, Carmella SG, Rodrigues EG, Christiani DC.

Cancer Epidemiol Biomarkers Prev. 2005 Mar;14(3):687-92.


CYP1A1, GSTM1, and GSTP1 genetic polymorphisms and urinary 1-hydroxypyrene excretion in non-occupationally exposed individuals.

Nerurkar PV, Okinaka L, Aoki C, Seifried A, Lum-Jones A, Wilkens LR, Le Marchand L.

Cancer Epidemiol Biomarkers Prev. 2000 Oct;9(10):1119-22.


Metabolites of the Polycyclic Aromatic Hydrocarbon Phenanthrene in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.

Patel YM, Park SL, Carmella SG, Paiano V, Olvera N, Stram DO, Haiman CA, Le Marchand L, Hecht SS.

PLoS One. 2016 Jun 8;11(6):e0156203. doi: 10.1371/journal.pone.0156203. eCollection 2016.


Occupational exposure to polycyclic aromatic hydrocarbons in German industries: association between exogenous exposure and urinary metabolites and its modulation by enzyme polymorphisms.

Rihs HP, Pesch B, Kappler M, Rabstein S, Rossbach B, Angerer J, Scherenberg M, Adams A, Wilhelm M, Seidel A, Brüning T.

Toxicol Lett. 2005 Jul 4;157(3):241-55. Epub 2005 Apr 8.


Immediate consequences of cigarette smoking: rapid formation of polycyclic aromatic hydrocarbon diol epoxides.

Zhong Y, Carmella SG, Upadhyaya P, Hochalter JB, Rauch D, Oliver A, Jensen J, Hatsukami D, Wang J, Zimmerman C, Hecht SS.

Chem Res Toxicol. 2011 Feb 18;24(2):246-52. doi: 10.1021/tx100345x. Epub 2010 Dec 27.


Urinary metabolites of a polycyclic aromatic hydrocarbon and volatile organic compounds in relation to lung cancer development in lifelong never smokers in the Shanghai Cohort Study.

Yuan JM, Butler LM, Gao YT, Murphy SE, Carmella SG, Wang R, Nelson HH, Hecht SS.

Carcinogenesis. 2014 Feb;35(2):339-45. doi: 10.1093/carcin/bgt352. Epub 2013 Oct 22.


GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population.

Hung RJ, Boffetta P, Brennan P, Malaveille C, Hautefeuille A, Donato F, Gelatti U, Spaliviero M, Placidi D, Carta A, Scotto di Carlo A, Porru S.

Int J Cancer. 2004 Jul 1;110(4):598-604.


Associations between both genetic and environmental biomarkers and lung cancer: evidence of a greater risk of lung cancer in women smokers.

Tang DL, Rundle A, Warburton D, Santella RM, Tsai WY, Chiamprasert S, Hsu YZ, Perera FP.

Carcinogenesis. 1998 Nov;19(11):1949-53.


Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns.

Wang S, Chanock S, Tang D, Li Z, Jedrychowski W, Perera FP.

Cancer Epidemiol Biomarkers Prev. 2008 Feb;17(2):405-13. doi: 10.1158/1055-9965.EPI-07-0695.

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