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Items: 1 to 20 of 98

1.

A genetic library screen for signaling proteins that interact with phosphorylated T cell costimulatory receptors.

Zang X, Loke P, Kim J, Wojnoonski K, Kusdra L, Allison JP.

Genomics. 2006 Dec;88(6):841-845. doi: 10.1016/j.ygeno.2006.08.012. Epub 2006 Oct 2.

2.

Inducible costimulator facilitates T-dependent B cell activation by augmenting IL-4 translation.

Gigoux M, Lovato A, Leconte J, Leung J, Sonenberg N, Suh WK.

Mol Immunol. 2014 May;59(1):46-54. doi: 10.1016/j.molimm.2014.01.008. Epub 2014 Jan 31.

PMID:
24486724
3.

Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase.

Gigoux M, Shang J, Pak Y, Xu M, Choe J, Mak TW, Suh WK.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20371-6. doi: 10.1073/pnas.0911573106. Epub 2009 Nov 13.

4.
5.

Inducible costimulator (ICOS) potentiates TCR-induced calcium flux by augmenting PLCγ1 activation and actin remodeling.

Leconte J, Bagherzadeh Yazdchi S, Panneton V, Suh WK.

Mol Immunol. 2016 Nov;79:38-46. doi: 10.1016/j.molimm.2016.09.022. Epub 2016 Sep 29.

PMID:
27693916
6.

The role of costimulation in antibody deficiencies: ICOS and common variable immunodeficiency.

Yong PF, Salzer U, Grimbacher B.

Immunol Rev. 2009 May;229(1):101-13. doi: 10.1111/j.1600-065X.2009.00764.x. Review.

PMID:
19426217
7.

A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS).

Harada Y, Ohgai D, Watanabe R, Okano K, Koiwai O, Tanabe K, Toma H, Altman A, Abe R.

J Exp Med. 2003 Jan 20;197(2):257-62.

8.

ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling.

Watanabe M, Watanabe S, Hara Y, Harada Y, Kubo M, Tanabe K, Toma H, Abe R.

J Immunol. 2005 Feb 15;174(4):1989-96.

9.

Biased binding of class IA phosphatidyl inositol 3-kinase subunits to inducible costimulator (CD278).

Acosta YY, Zafra MP, Ojeda G, Bernardone IS, Dianzani U, Portolés P, Rojo JM.

Cell Mol Life Sci. 2011 Sep;68(18):3065-79. doi: 10.1007/s00018-010-0606-1. Epub 2010 Dec 28.

PMID:
21188463
10.

ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse.

Fos C, Salles A, Lang V, Carrette F, Audebert S, Pastor S, Ghiotto M, Olive D, Bismuth G, Nunès JA.

J Immunol. 2008 Aug 1;181(3):1969-77.

11.

IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain-containing protein tyrosine phosphatase 1.

Taylor A, Akdis M, Joss A, Akkoç T, Wenig R, Colonna M, Daigle I, Flory E, Blaser K, Akdis CA.

J Allergy Clin Immunol. 2007 Jul;120(1):76-83. Epub 2007 May 25.

PMID:
17531298
13.

The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells.

Paulos CM, Carpenito C, Plesa G, Suhoski MM, Varela-Rohena A, Golovina TN, Carroll RG, Riley JL, June CH.

Sci Transl Med. 2010 Oct 27;2(55):55ra78. doi: 10.1126/scitranslmed.3000448.

14.

Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival.

Nanji SA, Hancock WW, Anderson CC, Adams AB, Luo B, Schur CD, Pawlick RL, Wang L, Coyle AJ, Larsen CP, Shapiro AM.

Am J Transplant. 2004 Apr;4(4):526-36.

15.

Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity.

Vermeiren J, Ceuppens JL, Van Ghelue M, Witters P, Bullens D, Mages HW, Kroczek RA, Van Gool SW.

J Immunol. 2004 May 1;172(9):5371-8.

16.

Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity.

Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, Berry G, DeKruyff RH, Umetsu DT.

Nat Med. 2002 Sep;8(9):1024-32. Epub 2002 Jul 29.

PMID:
12145647
19.

Mechanisms of H4/ICOS costimulation: effects on proximal TCR signals and MAP kinase pathways.

Feito MJ, Vaschetto R, Criado G, Sánchez A, Chiocchetti A, Jiménez-Periáñez A, Dianzani U, Portoles P, Rojo JM.

Eur J Immunol. 2003 Jan;33(1):204-14.

20.

AILIM/ICOS-mediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade.

Nukada Y, Okamoto N, Konakahara S, Tezuka K, Ohashi K, Mizuno K, Tsuji T.

Int Immunol. 2006 Dec;18(12):1815-24. Epub 2006 Oct 31.

PMID:
17077177

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