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Items: 1 to 20 of 106


Mammalian lin-7 stabilizes polarity protein complexes.

Straight SW, Pieczynski JN, Whiteman EL, Liu CJ, Margolis B.

J Biol Chem. 2006 Dec 8;281(49):37738-47. Epub 2006 Oct 1.


The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation.

Stucke VM, Timmerman E, Vandekerckhove J, Gevaert K, Hall A.

Mol Biol Cell. 2007 May;18(5):1744-55. Epub 2007 Mar 1.


Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells.

Fogg VC, Liu CJ, Margolis B.

J Cell Sci. 2005 Jul 1;118(Pt 13):2859-69.


Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization.

Satohisa S, Chiba H, Osanai M, Ohno S, Kojima T, Saito T, Sawada N.

Exp Cell Res. 2005 Oct 15;310(1):66-78.


The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost.

Roh MH, Makarova O, Liu CJ, Shin K, Lee S, Laurinec S, Goyal M, Wiggins R, Margolis B.

J Cell Biol. 2002 Apr 1;157(1):161-72. Epub 2002 Apr 1.


LIN7 mediates the recruitment of IRSp53 to tight junctions.

Massari S, Perego C, Padovano V, D'Amico A, Raimondi A, Francolini M, Pietrini G.

Traffic. 2009 Feb;10(2):246-57. doi: 10.1111/j.1600-0854.2008.00854.x. Epub 2008 Nov 11.


PATJ regulates tight junction formation and polarity in mammalian epithelial cells.

Shin K, Straight S, Margolis B.

J Cell Biol. 2005 Feb 28;168(5):705-11.


Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode.

Zhang J, Yang X, Wang Z, Zhou H, Xie X, Shen Y, Long J.

J Biol Chem. 2012 Mar 30;287(14):11132-40. doi: 10.1074/jbc.M111.321216. Epub 2012 Feb 15.


FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex.

Gosens I, Sessa A, den Hollander AI, Letteboer SJ, Belloni V, Arends ML, Le Bivic A, Cremers FP, Broccoli V, Roepman R.

Exp Cell Res. 2007 Nov 15;313(19):3959-70. Epub 2007 Sep 7.


A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.

Wells CD, Fawcett JP, Traweger A, Yamanaka Y, Goudreault M, Elder K, Kulkarni S, Gish G, Virag C, Lim C, Colwill K, Starostine A, Metalnikov P, Pawson T.

Cell. 2006 May 5;125(3):535-48.


Direct interaction of two polarity complexes implicated in epithelial tight junction assembly.

Hurd TW, Gao L, Roh MH, Macara IG, Margolis B.

Nat Cell Biol. 2003 Feb;5(2):137-42.


Loss of PALS1 expression leads to tight junction and polarity defects.

Straight SW, Shin K, Fogg VC, Fan S, Liu CJ, Roh M, Margolis B.

Mol Biol Cell. 2004 Apr;15(4):1981-90. Epub 2004 Jan 12.


The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions.

Roh MH, Liu CJ, Laurinec S, Margolis B.

J Biol Chem. 2002 Jul 26;277(30):27501-9. Epub 2002 May 20.


Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins.

Adachi M, Hamazaki Y, Kobayashi Y, Itoh M, Tsukita S, Furuse M, Tsukita S.

Mol Cell Biol. 2009 May;29(9):2372-89. doi: 10.1128/MCB.01505-08. Epub 2009 Mar 2.


PATJ connects and stabilizes apical and lateral components of tight junctions in human intestinal cells.

Michel D, Arsanto JP, Massey-Harroche D, B├ęclin C, Wijnholds J, Le Bivic A.

J Cell Sci. 2005 Sep 1;118(Pt 17):4049-57.


PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.

Stenzel N, Fetzer CP, Heumann R, Erdmann KS.

J Cell Sci. 2009 Sep 15;122(Pt 18):3374-84. doi: 10.1242/jcs.046854. Epub 2009 Aug 25.


PALS1 specifies the localization of ezrin to the apical membrane of gastric parietal cells.

Cao X, Ding X, Guo Z, Zhou R, Wang F, Long F, Wu F, Bi F, Wang Q, Fan D, Forte JG, Teng M, Yao X.

J Biol Chem. 2005 Apr 8;280(14):13584-92. Epub 2005 Jan 27.


Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.

Li Y, Wei Z, Yan Y, Wan Q, Du Q, Zhang M.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17444-9. doi: 10.1073/pnas.1416515111. Epub 2014 Nov 10.


Self-association of PAR-3-mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions.

Mizuno K, Suzuki A, Hirose T, Kitamura K, Kutsuzawa K, Futaki M, Amano Y, Ohno S.

J Biol Chem. 2003 Aug 15;278(33):31240-50. Epub 2003 May 19.

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