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Items: 1 to 20 of 133

1.

Proprotein convertases: lessons from knockouts.

Scamuffa N, Calvo F, Chrétien M, Seidah NG, Khatib AM.

FASEB J. 2006 Oct;20(12):1954-63. Review.

PMID:
17012247
2.

The proprotein convertases are potential targets in the treatment of dyslipidemia.

Seidah NG, Prat A.

J Mol Med (Berl). 2007 Jul;85(7):685-96. Epub 2007 Mar 10. Review.

PMID:
17351764
3.

Knock-out mouse models of proprotein convertases: unique functions or redundancy?

Creemers JW, Khatib AM.

Front Biosci. 2008 May 1;13:4960-71. Review.

PMID:
18508561
4.

The biology and therapeutic targeting of the proprotein convertases.

Seidah NG, Prat A.

Nat Rev Drug Discov. 2012 May;11(5):367-83. Review.

PMID:
22679642
5.

The proprotein convertases and their implication in sterol and/or lipid metabolism.

Seidah NG, Khatib AM, Prat A.

Biol Chem. 2006 Jul;387(7):871-7. Review.

PMID:
16913836
6.

The activation and physiological functions of the proprotein convertases.

Seidah NG, Mayer G, Zaid A, Rousselet E, Nassoury N, Poirier S, Essalmani R, Prat A.

Int J Biochem Cell Biol. 2008;40(6-7):1111-25. doi: 10.1016/j.biocel.2008.01.030. Epub 2008 Feb 8. Review.

PMID:
18343183
7.

What lies ahead for the proprotein convertases?

Seidah NG.

Ann N Y Acad Sci. 2011 Mar;1220:149-61. doi: 10.1111/j.1749-6632.2010.05883.x. Review.

PMID:
21388412
8.

The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions.

Seidah NG, Sadr MS, Chrétien M, Mbikay M.

J Biol Chem. 2013 Jul 26;288(30):21473-81. doi: 10.1074/jbc.R113.481549. Epub 2013 Jun 17. Review.

10.

The Proprotein Convertases in Hypercholesterolemia and Cardiovascular Diseases: Emphasis on Proprotein Convertase Subtilisin/Kexin 9.

Seidah NG, Abifadel M, Prost S, Boileau C, Prat A.

Pharmacol Rev. 2017 Jan;69(1):33-52. Review.

PMID:
27920219
11.

The proprotein convertases furin and PACE4 play a significant role in tumor progression.

Bassi DE, Mahloogi H, Klein-Szanto AJ.

Mol Carcinog. 2000 Jun;28(2):63-9. Review.

PMID:
10900462
12.

The proprotein convertases, 20 years later.

Seidah NG.

Methods Mol Biol. 2011;768:23-57. doi: 10.1007/978-1-61779-204-5_3. Review.

PMID:
21805237
13.

Precursor convertases in the secretory pathway, cytosol and extracellular milieu.

Seidah NG, Prat A.

Essays Biochem. 2002;38:79-94. Review.

PMID:
12463163
14.

Inhibitors of proprotein convertases.

Basak A.

J Mol Med (Berl). 2005 Nov;83(11):844-55. Epub 2005 Oct 8. Review.

PMID:
16215768
15.

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.

Seidah NG, Chrétien M, Day R.

Biochimie. 1994;76(3-4):197-209. Review.

PMID:
7819324
16.

Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity.

Henrich S, Lindberg I, Bode W, Than ME.

J Mol Biol. 2005 Jan 14;345(2):211-27.

PMID:
15571716
17.

Proprotein convertases: "master switches" in the regulation of tumor growth and progression.

Bassi DE, Fu J, Lopez de Cicco R, Klein-Szanto AJ.

Mol Carcinog. 2005 Nov;44(3):151-61. Review.

PMID:
16167351
18.

Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system.

Poirier S, Prat A, Marcinkiewicz E, Paquin J, Chitramuthu BP, Baranowski D, Cadieux B, Bennett HP, Seidah NG.

J Neurochem. 2006 Aug;98(3):838-50.

19.

Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.

Van de Ven WJ, Roebroek AJ, Van Duijnhoven HL.

Crit Rev Oncog. 1993;4(2):115-36. Review.

PMID:
8420571
20.

Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.

Scamuffa N, Basak A, Lalou C, Wargnier A, Marcinkiewicz J, Siegfried G, Chrétien M, Calvo F, Seidah NG, Khatib AM.

Gut. 2008 Nov;57(11):1573-82. doi: 10.1136/gut.2007.141812. Epub 2008 Jul 29.

PMID:
18664504

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