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Items: 1 to 20 of 172

1.

Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study.

Shapiro TA, Fahey JW, Dinkova-Kostova AT, Holtzclaw WD, Stephenson KK, Wade KL, Ye L, Talalay P.

Nutr Cancer. 2006;55(1):53-62.

PMID:
16965241
2.

Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans.

Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P.

Cancer Epidemiol Biomarkers Prev. 2001 May;10(5):501-8.

3.

Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables.

Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P.

Cancer Epidemiol Biomarkers Prev. 1998 Dec;7(12):1091-100.

4.

Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans.

Ye L, Dinkova-Kostova AT, Wade KL, Zhang Y, Shapiro TA, Talalay P.

Clin Chim Acta. 2002 Feb;316(1-2):43-53. Erratum in: Clin Chim Acta 2002 Jul;321(1-2):127-9.

PMID:
11750273
5.

Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China.

Kensler TW, Chen JG, Egner PA, Fahey JW, Jacobson LP, Stephenson KK, Ye L, Coady JL, Wang JB, Wu Y, Sun Y, Zhang QN, Zhang BC, Zhu YR, Qian GS, Carmella SG, Hecht SS, Benning L, Gange SJ, Groopman JD, Talalay P.

Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2605-13.

6.

Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.

Clarke JD, Hsu A, Riedl K, Bella D, Schwartz SJ, Stevens JF, Ho E.

Pharmacol Res. 2011 Nov;64(5):456-63. doi: 10.1016/j.phrs.2011.07.005. Epub 2011 Jul 26.

7.

Enhancing sulforaphane absorption and excretion in healthy men through the combined consumption of fresh broccoli sprouts and a glucoraphanin-rich powder.

Cramer JM, Teran-Garcia M, Jeffery EH.

Br J Nutr. 2012 May;107(9):1333-8. doi: 10.1017/S0007114511004429. Epub 2011 Sep 13.

PMID:
21910945
8.

Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase.

Fahey JW, Holtzclaw WD, Wehage SL, Wade KL, Stephenson KK, Talalay P.

PLoS One. 2015 Nov 2;10(11):e0140963. doi: 10.1371/journal.pone.0140963. eCollection 2015.

9.

Cloning of genes related to aliphatic glucosinolate metabolism and the mechanism of sulforaphane accumulation in broccoli sprouts under jasmonic acid treatment.

Guo L, Yang R, Gu Z.

J Sci Food Agric. 2016 Oct;96(13):4329-36. doi: 10.1002/jsfa.7629. Epub 2016 Mar 4.

PMID:
26786856
10.

Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract.

Atwell LL, Hsu A, Wong CP, Stevens JF, Bella D, Yu TW, Pereira CB, Löhr CV, Christensen JM, Dashwood RH, Williams DE, Shannon J, Ho E.

Mol Nutr Food Res. 2015 Mar;59(3):424-33. doi: 10.1002/mnfr.201400674. Epub 2015 Jan 22.

11.

Urinary excretion of total isothiocyanates from cruciferous vegetables shows high dose-response relationship and may be a useful biomarker for isothiocyanate exposure.

Kristensen M, Krogholm KS, Frederiksen H, Bügel SH, Rasmussen SE.

Eur J Nutr. 2007 Oct;46(7):377-82. Epub 2007 Aug 23.

PMID:
17717627
12.
13.

Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement.

Clarke JD, Riedl K, Bella D, Schwartz SJ, Stevens JF, Ho E.

J Agric Food Chem. 2011 Oct 26;59(20):10955-63. doi: 10.1021/jf202887c. Epub 2011 Sep 30.

14.

Isothiocyanate metabolism, distribution, and interconversion in mice following consumption of thermally processed broccoli sprouts or purified sulforaphane.

Bricker GV, Riedl KM, Ralston RA, Tober KL, Oberyszyn TM, Schwartz SJ.

Mol Nutr Food Res. 2014 Oct;58(10):1991-2000. doi: 10.1002/mnfr.201400104. Epub 2014 Jul 28.

15.

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens.

Fahey JW, Zhang Y, Talalay P.

Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10367-72.

16.

Hydrolysis of glucosinolates to isothiocyanates after ingestion of raw or microwaved cabbage by human volunteers.

Rouzaud G, Young SA, Duncan AJ.

Cancer Epidemiol Biomarkers Prev. 2004 Jan;13(1):125-31.

17.

A new ultra-rapid UHPLC/MS/MS method for assessing glucoraphanin and sulforaphane bioavailability in human urine.

Dominguez-Perles R, Medina S, Moreno DÁ, García-Viguera C, Ferreres F, Gil-Izquierdo Á.

Food Chem. 2014 Jan 15;143:132-8. doi: 10.1016/j.foodchem.2013.07.116. Epub 2013 Jul 30.

PMID:
24054222
18.

Frugal chemoprevention: targeting Nrf2 with foods rich in sulforaphane.

Yang L, Palliyaguru DL, Kensler TW.

Semin Oncol. 2016 Feb;43(1):146-53. doi: 10.1053/j.seminoncol.2015.09.013. Epub 2015 Sep 8. Review.

19.

Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China.

Egner PA, Chen JG, Wang JB, Wu Y, Sun Y, Lu JH, Zhu J, Zhang YH, Chen YS, Friesen MD, Jacobson LP, Muñoz A, Ng D, Qian GS, Zhu YR, Chen TY, Botting NP, Zhang Q, Fahey JW, Talalay P, Groopman JD, Kensler TW.

Cancer Prev Res (Phila). 2011 Mar;4(3):384-95. doi: 10.1158/1940-6207.CAPR-10-0296.

20.

Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli.

Gasper AV, Al-Janobi A, Smith JA, Bacon JR, Fortun P, Atherton C, Taylor MA, Hawkey CJ, Barrett DA, Mithen RF.

Am J Clin Nutr. 2005 Dec;82(6):1283-91. Erratum in: Am J Clin Nutr. 2006 Mar;83(3):724.

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