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Items: 1 to 20 of 93

1.

Forskolin, an inducer of cAMP, up-regulates acetylcholinesterase expression and protects against organophosphate exposure in neuro 2A cells.

Curtin BF, Pal N, Gordon RK, Nambiar MP.

Mol Cell Biochem. 2006 Oct;290(1-2):23-32. Epub 2006 Aug 19.

PMID:
16924422
2.

Histone acetylase inhibitor trichostatin A induces acetylcholinesterase expression and protects against organophosphate exposure.

Curtin BF, Tetz LM, Compton JR, Doctor BP, Gordon RK, Nambiar MP.

J Cell Biochem. 2005 Nov 1;96(4):839-49.

PMID:
16149071
3.

Resveratrol induces catalytic bioscavenger paraoxonase 1 expression and protects against chemical warfare nerve agent toxicity in human cell lines.

Curtin BF, Seetharam KI, Dhoieam P, Gordon RK, Doctor BP, Nambiar MP.

J Cell Biochem. 2008 Apr 1;103(5):1524-35.

PMID:
17879943
4.

Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase.

Mazor O, Cohen O, Kronman C, Raveh L, Stein D, Ordentlich A, Shafferman A.

Mol Pharmacol. 2008 Sep;74(3):755-63. doi: 10.1124/mol.108.047449. Epub 2008 Jun 3.

5.

Transcriptional induction of cholinesterase expression and protection against chemical warfare nerve agents.

Nambiar MP, Curtin BF, Pal N, Compton JR, Doctor BP, Gordon RK.

Chem Biol Interact. 2005 Dec 15;157-158:409-10.

PMID:
16429504
6.

Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman.

Gordon RK, Haigh JR, Garcia GE, Feaster SR, Riel MA, Lenz DE, Aisen PS, Doctor BP.

Chem Biol Interact. 2005 Dec 15;157-158:239-46. Epub 2005 Oct 26.

PMID:
16256090
8.

Gene transfer of acetylcholinesterase protects the knockout mouse from the toxicity of DFP.

Li B, Duysen EG, Lockridge O.

J Mol Neurosci. 2006;30(1-2):79-80.

PMID:
17192637
9.

Acetylcholinesterase-Fc Fusion Protein (AChE-Fc): A Novel Potential Organophosphate Bioscavenger with Extended Plasma Half-Life.

Noy-Porat T, Cohen O, Ehrlich S, Epstein E, Alcalay R, Mazor O.

Bioconjug Chem. 2015 Aug 19;26(8):1753-8. doi: 10.1021/acs.bioconjchem.5b00305. Epub 2015 Jul 8.

PMID:
26121420
10.
11.

Comparison of inhibition kinetics of several organophosphates, including some nerve agent surrogates, using human erythrocyte and rat and mouse brain acetylcholinesterase.

Coban A, Carr RL, Chambers HW, Willeford KO, Chambers JE.

Toxicol Lett. 2016 Apr 25;248:39-45. doi: 10.1016/j.toxlet.2016.03.002. Epub 2016 Mar 7.

12.
13.

Protection by pyridostigmine bromide of marmoset hemi-diaphragm acetylcholinesterase activity after soman exposure.

Haigh JR, Adler M, Apland JP, Deshpande SS, Barham CB, Desmond P, Koplovitz I, Lenz DE, Gordon RK.

Chem Biol Interact. 2010 Sep 6;187(1-3):416-20. doi: 10.1016/j.cbi.2010.02.003. Epub 2010 Feb 8.

PMID:
20144889
15.

Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase.

Barakat NH, Zheng X, Gilley CB, MacDonald M, Okolotowicz K, Cashman JR, Vyas S, Beck JM, Hadad CM, Zhang J.

Chem Res Toxicol. 2009 Oct;22(10):1669-79. doi: 10.1021/tx900096j.

17.

Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning.

Saxena A, Maxwell DM, Quinn DM, Radić Z, Taylor P, Doctor BP.

Biochem Pharmacol. 1997 Jul 15;54(2):269-74.

PMID:
9271331
18.

Molecular mechanisms underlying forskolin-mediated up-regulation of human dopamine D2L receptors.

Wanderoy MH, Westlind-Danielsson A.

Cell Mol Neurobiol. 1997 Oct;17(5):547-55.

PMID:
9353595
19.

Protection of red blood cell acetylcholinesterase by oral huperzine A against ex vivo soman exposure: next generation prophylaxis and sequestering of acetylcholinesterase over butyrylcholinesterase.

Haigh JR, Johnston SR, Peppernay A, Mattern PJ, Garcia GE, Doctor BP, Gordon RK, Aisen PS.

Chem Biol Interact. 2008 Sep 25;175(1-3):380-6. doi: 10.1016/j.cbi.2008.04.033. Epub 2008 May 3.

PMID:
18572153
20.

Recombinant paraoxonase 1 protects against sarin and soman toxicity following microinstillation inhalation exposure in guinea pigs.

Valiyaveettil M, Alamneh Y, Rezk P, Perkins MW, Sciuto AM, Doctor BP, Nambiar MP.

Toxicol Lett. 2011 May 10;202(3):203-8. doi: 10.1016/j.toxlet.2011.02.007. Epub 2011 Feb 15.

PMID:
21329748

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