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Items: 1 to 20 of 115

1.

Integrins in drug targeting-RGD templates in toxins.

Lu X, Lu D, Scully MF, Kakkar VV.

Curr Pharm Des. 2006;12(22):2749-69. Review.

PMID:
16918409
2.

Modulation of integrin-binding selectivity by mutation within the RGD-loop of snake venom proteins: a novel drug development approach.

Lu X, Lu D, Scully MF, Kakkar VV.

Curr Med Chem Cardiovasc Hematol Agents. 2003 Jun;1(2):189-96. Review.

PMID:
15320698
3.

Structural requirements of MLD-containing disintegrins for functional interaction with alpha 4 beta 1 and alpha 9 beta1 integrins.

Bazan-Socha S, Kisiel DG, Young B, Theakston RD, Calvete JJ, Sheppard D, Marcinkiewicz C.

Biochemistry. 2004 Feb 17;43(6):1639-47.

PMID:
14769041
5.

Crystal structure of trimestatin, a disintegrin containing a cell adhesion recognition motif RGD.

Fujii Y, Okuda D, Fujimoto Z, Horii K, Morita T, Mizuno H.

J Mol Biol. 2003 Oct 3;332(5):1115-22.

PMID:
14499613
6.

Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting.

Meyer A, Auernheimer J, Modlinger A, Kessler H.

Curr Pharm Des. 2006;12(22):2723-47. Review.

PMID:
16918408
9.

The effect of the single substitution of arginine within the RGD tripeptide motif of a modified neurotoxin dendroaspin on its activity of platelet aggregation and cell adhesion.

Lu X, Davies J, Lu D, Xia M, Wattam B, Shang D, Sun Y, Scully M, Kakkar V.

Cell Commun Adhes. 2006 May-Jun;13(3):171-83.

PMID:
16798616
10.

Integrin binding characteristics of the disintegrin-like domain of ADAM-15.

Lu D, Chung KF, Xia M, Lu X, Scully M, Kakkar V.

Thromb Haemost. 2006 Nov;96(5):642-51.

PMID:
17080222
11.

Evolution of snake venom disintegrins by positive Darwinian selection.

Juárez P, Comas I, González-Candelas F, Calvete JJ.

Mol Biol Evol. 2008 Nov;25(11):2391-407. doi: 10.1093/molbev/msn179. Epub 2008 Aug 13.

PMID:
18701431
12.

Snake venom metalloproteinase containing a disintegrin-like domain, its structure-activity relationships at interacting with integrins.

Lu X, Lu D, Scully MF, Kakkar VV.

Curr Med Chem Cardiovasc Hematol Agents. 2005 Jul;3(3):249-60. Review.

PMID:
15974889
13.

Solution structure of gamma-bungarotoxin: the functional significance of amino acid residues flanking the RGD motif in integrin binding.

Shiu JH, Chen CY, Chang LS, Chen YC, Chen YC, Lo YH, Liu YC, Chuang WJ.

Proteins. 2004 Dec 1;57(4):839-49.

PMID:
15390258
14.
15.

Characterisation of a novel, high affinity and selective αvβ6 integrin RGD-mimetic radioligand.

Hall ER, Bibby LI, Slack RJ.

Biochem Pharmacol. 2016 Oct 1;117:88-96. doi: 10.1016/j.bcp.2016.08.003. Epub 2016 Aug 5.

PMID:
27501918
16.

Structural analysis of integrin recognition and the inhibition of integrin-mediated cell functions by novel nonpeptidic surrogates of the Arg-Gly-Asp sequence.

Greenspoon N, Hershkoviz R, Alon R, Varon D, Shenkman B, Marx G, Federman S, Kapustina G, Lider O.

Biochemistry. 1993 Feb 2;32(4):1001-8.

PMID:
8093840
17.

Dynamics and functional differences between dendroaspin and rhodostomin: insights into protein scaffolds in integrin recognition.

Cheng CH, Chen YC, Shiu JH, Chang YT, Chang YS, Huang CH, Chen CY, Chuang WJ.

Protein Sci. 2012 Dec;21(12):1872-84. doi: 10.1002/pro.2169. Epub 2012 Nov 6.

18.
19.

ADAM-15 disintegrin-like domain structure and function.

Lu D, Scully M, Kakkar V, Lu X.

Toxins (Basel). 2010 Oct;2(10):2411-27. doi: 10.3390/toxins2102411. Epub 2010 Oct 19. Review.

20.

Applications of snake venom components to modulate integrin activities in cell-matrix interactions.

Marcinkiewicz C.

Int J Biochem Cell Biol. 2013 Sep;45(9):1974-86. doi: 10.1016/j.biocel.2013.06.009. Epub 2013 Jun 26. Review.

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