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Items: 1 to 20 of 126


Single-molecule analysis of dynein processivity and stepping behavior.

Reck-Peterson SL, Yildiz A, Carter AP, Gennerich A, Zhang N, Vale RD.

Cell. 2006 Jul 28;126(2):335-48.


Molecular motors take tension in stride.

Spudich JA.

Cell. 2006 Jul 28;126(2):242-4.


Reconstitution of dynein transport to the microtubule plus end by kinesin.

Roberts AJ, Goodman BS, Reck-Peterson SL.

Elife. 2014 Jun 10;3:e02641. doi: 10.7554/eLife.02641.


Head-head coordination is required for the processive motion of cytoplasmic dynein, an AAA+ molecular motor.

Shima T, Imamula K, Kon T, Ohkura R, Sutoh K.

J Struct Biol. 2006 Oct;156(1):182-9. Epub 2006 Apr 21.


Force-induced bidirectional stepping of cytoplasmic dynein.

Gennerich A, Carter AP, Reck-Peterson SL, Vale RD.

Cell. 2007 Nov 30;131(5):952-65.


Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domains.

DeWitt MA, Chang AY, Combs PA, Yildiz A.

Science. 2012 Jan 13;335(6065):221-5. doi: 10.1126/science.1215804. Epub 2011 Dec 8.


Bidirectional helical motility of cytoplasmic dynein around microtubules.

Can S, Dewitt MA, Yildiz A.

Elife. 2014 Jul 28;3:e03205. doi: 10.7554/eLife.03205.


Tension on the linker gates the ATP-dependent release of dynein from microtubules.

Cleary FB, Dewitt MA, Bilyard T, Htet ZM, Belyy V, Chan DD, Chang AY, Yildiz A.

Nat Commun. 2014 Aug 11;5:4587. doi: 10.1038/ncomms5587.


She1-mediated inhibition of dynein motility along astral microtubules promotes polarized spindle movements.

Markus SM, Kalutkiewicz KA, Lee WL.

Curr Biol. 2012 Dec 4;22(23):2221-30. doi: 10.1016/j.cub.2012.10.017. Epub 2012 Nov 8.


Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains.

Nicholas MP, Berger F, Rao L, Brenner S, Cho C, Gennerich A.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):6371-6. doi: 10.1073/pnas.1417422112. Epub 2015 May 4.


Cytoplasmic dynein transports cargos via load-sharing between the heads.

Belyy V, Hendel NL, Chien A, Yildiz A.

Nat Commun. 2014 Nov 26;5:5544. doi: 10.1038/ncomms6544.


The yeast dynein Dyn2-Pac11 complex is a dynein dimerization/processivity factor: structural and single-molecule characterization.

Rao L, Romes EM, Nicholas MP, Brenner S, Tripathy A, Gennerich A, Slep KC.

Mol Biol Cell. 2013 Aug;24(15):2362-77. doi: 10.1091/mbc.E13-03-0166. Epub 2013 Jun 12.


Dynein and kinesin share an overlapping microtubule-binding site.

Mizuno N, Toba S, Edamatsu M, Watai-Nishii J, Hirokawa N, Toyoshima YY, Kikkawa M.

EMBO J. 2004 Jul 7;23(13):2459-67. Epub 2004 Jun 3.


Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains.

Tanenbaum ME, Vale RD, McKenney RJ.

Elife. 2013 Sep 3;2:e00943. doi: 10.7554/eLife.00943.


Autoinhibitory and other autoregulatory elements within the dynein motor domain.

Vallee RB, Höök P.

J Struct Biol. 2006 Oct;156(1):175-81. Epub 2006 Mar 29. Review.


Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor.

Huang J, Roberts AJ, Leschziner AE, Reck-Peterson SL.

Cell. 2012 Aug 31;150(5):975-86. doi: 10.1016/j.cell.2012.07.022.


Building complexity: an in vitro study of cytoplasmic dynein with in vivo implications.

Mallik R, Petrov D, Lex SA, King SJ, Gross SP.

Curr Biol. 2005 Dec 6;15(23):2075-85.


Crystal clear insights into how the dynein motor moves.

Carter AP.

J Cell Sci. 2013 Feb 1;126(Pt 3):705-13. doi: 10.1242/jcs.120725. Epub 2013 Mar 22.


The role of the dynein stalk in cytoplasmic and flagellar motility.

Gee M, Vallee R.

Eur Biophys J. 1998;27(5):466-73. Review.


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