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Items: 1 to 20 of 197

1.

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.

Gross O, Gewies A, Finger K, Schäfer M, Sparwasser T, Peschel C, Förster I, Ruland J.

Nature. 2006 Aug 10;442(7103):651-6. Epub 2006 Jul 12.

PMID:
16862125
2.

Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells.

Xu S, Huo J, Lee KG, Kurosaki T, Lam KP.

J Biol Chem. 2009 Mar 13;284(11):7038-46. doi: 10.1074/jbc.M806650200. Epub 2009 Jan 9.

3.

Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity.

Strasser D, Neumann K, Bergmann H, Marakalala MJ, Guler R, Rojowska A, Hopfner KP, Brombacher F, Urlaub H, Baier G, Brown GD, Leitges M, Ruland J.

Immunity. 2012 Jan 27;36(1):32-42. doi: 10.1016/j.immuni.2011.11.015.

4.

CARD9 mediates dectin-2-induced IkappaBalpha kinase ubiquitination leading to activation of NF-kappaB in response to stimulation by the hyphal form of Candida albicans.

Bi L, Gojestani S, Wu W, Hsu YM, Zhu J, Ariizumi K, Lin X.

J Biol Chem. 2010 Aug 20;285(34):25969-77. doi: 10.1074/jbc.M110.131300. Epub 2010 Jun 9.

5.

C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation.

Zhao XQ, Zhu LL, Chang Q, Jiang C, You Y, Luo T, Jia XM, Lin X.

J Biol Chem. 2014 Oct 24;289(43):30052-62. doi: 10.1074/jbc.M114.588574. Epub 2014 Sep 8.

6.

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors.

Hara H, Ishihara C, Takeuchi A, Imanishi T, Xue L, Morris SW, Inui M, Takai T, Shibuya A, Saijo S, Iwakura Y, Ohno N, Koseki H, Yoshida H, Penninger JM, Saito T.

Nat Immunol. 2007 Jun;8(6):619-29. Epub 2007 May 7.

PMID:
17486093
7.

Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-kappaB and MAPK activation to selectively control cytokine production.

Gross O, Grupp C, Steinberg C, Zimmermann S, Strasser D, Hannesschläger N, Reindl W, Jonsson H, Huo H, Littman DR, Peschel C, Yokoyama WM, Krug A, Ruland J.

Blood. 2008 Sep 15;112(6):2421-8. doi: 10.1182/blood-2007-11-123513. Epub 2008 Jan 11.

8.

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.

LeibundGut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E, Tybulewicz V, Brown GD, Ruland J, Reis e Sousa C.

Nat Immunol. 2007 Jun;8(6):630-8. Epub 2007 Apr 22.

PMID:
17450144
9.

Differential use of CARD9 by dectin-1 in macrophages and dendritic cells.

Goodridge HS, Shimada T, Wolf AJ, Hsu YM, Becker CA, Lin X, Underhill DM.

J Immunol. 2009 Jan 15;182(2):1146-54.

10.

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.

Werninghaus K, Babiak A, Gross O, Hölscher C, Dietrich H, Agger EM, Mages J, Mocsai A, Schoenen H, Finger K, Nimmerjahn F, Brown GD, Kirschning C, Heit A, Andersen P, Wagner H, Ruland J, Lang R.

J Exp Med. 2009 Jan 16;206(1):89-97. doi: 10.1084/jem.20081445. Epub 2009 Jan 12.

11.

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.

Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, Gross O, Verbeek JS, Ruland J, Tybulewicz V, Brown GD, Moita LF, Taylor PR, Reis e Sousa C.

J Exp Med. 2009 Aug 31;206(9):2037-51. doi: 10.1084/jem.20082818. Epub 2009 Aug 24.

12.

CARD9 mediates Dectin-1-induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity.

Jia XM, Tang B, Zhu LL, Liu YH, Zhao XQ, Gorjestani S, Hsu YM, Yang L, Guan JH, Xu GT, Lin X.

J Exp Med. 2014 Oct 20;211(11):2307-21. doi: 10.1084/jem.20132349. Epub 2014 Sep 29.

13.

Activation of NF-κB and respiratory burst following Aspergillus fumigatus stimulation of macrophages.

Sun H, Xu XY, Tian XL, Shao HT, Wu XD, Wang Q, Su X, Shi Y.

Immunobiology. 2014 Jan;219(1):25-36. doi: 10.1016/j.imbio.2013.06.013. Epub 2013 Jul 4.

PMID:
23886693
14.

Barley-derived beta-D-glucan induces immunostimulation via a dectin-1-mediated pathway.

Tada R, Ikeda F, Aoki K, Yoshikawa M, Kato Y, Adachi Y, Tanioka A, Ishibashi K, Tsubaki K, Ohno N.

Immunol Lett. 2009 Apr 27;123(2):144-8. doi: 10.1016/j.imlet.2009.03.005. Epub 2009 Mar 21.

PMID:
19428562
15.

The role of Dectin-1 in the host defence against fungal infections.

Drummond RA, Brown GD.

Curr Opin Microbiol. 2011 Aug;14(4):392-9. doi: 10.1016/j.mib.2011.07.001. Epub 2011 Jul 29. Review.

PMID:
21803640
16.

Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9.

Hara H, Ishihara C, Takeuchi A, Xue L, Morris SW, Penninger JM, Yoshida H, Saito T.

J Immunol. 2008 Jul 15;181(2):918-30.

17.

CARD-Bcl10-Malt1 signalosomes: missing link to NF-kappaB.

Wegener E, Krappmann D.

Sci STKE. 2007 May 1;2007(384):pe21.

PMID:
17473310
18.

CARD9 versus CARMA1 in innate and adaptive immunity.

Hara H, Saito T.

Trends Immunol. 2009 May;30(5):234-42. doi: 10.1016/j.it.2009.03.002. Epub 2009 Apr 7. Review.

PMID:
19359218
19.

CARD9 signaling in the innate immune response.

Ruland J.

Ann N Y Acad Sci. 2008 Nov;1143:35-44. doi: 10.1196/annals.1443.024. Review.

PMID:
19076343
20.

The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity.

Yang CS, Rodgers M, Min CK, Lee JS, Kingeter L, Lee JY, Jong A, Kramnik I, Lin X, Jung JU.

Cell Host Microbe. 2012 Mar 15;11(3):277-89. doi: 10.1016/j.chom.2012.01.019.

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