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Items: 1 to 20 of 156

1.

Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells.

Chute JP, Muramoto GG, Whitesides J, Colvin M, Safi R, Chao NJ, McDonnell DP.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11707-12.

2.

Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity.

Muramoto GG, Russell JL, Safi R, Salter AB, Himburg HA, Daher P, Meadows SK, Doan P, Storms RW, Chao NJ, McDonnell DP, Chute JP.

Stem Cells. 2010 Mar 31;28(3):523-34. doi: 10.1002/stem.299.

3.

Dual SP/ALDH functionalities refine the human hematopoietic Lin-CD34+CD38- stem/progenitor cell compartment.

Pierre-Louis O, Clay D, Brunet de la Grange P, Blazsek I, Desterke C, Guerton B, Blondeau C, Malfuson JV, Prat M, Bennaceur-Griscelli A, Lataillade JJ, Le Bousse-Kerdilès MC.

Stem Cells. 2009 Oct;27(10):2552-62. doi: 10.1002/stem.186.

4.

Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL.

Nishino T, Miyaji K, Ishiwata N, Arai K, Yui M, Asai Y, Nakauchi H, Iwama A.

Exp Hematol. 2009 Nov;37(11):1364-1377.e4. doi: 10.1016/j.exphem.2009.09.001.

PMID:
19744539
5.

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity.

Hess DA, Meyerrose TE, Wirthlin L, Craft TP, Herrbrich PE, Creer MH, Nolta JA.

Blood. 2004 Sep 15;104(6):1648-55.

6.

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells.

Hess DA, Wirthlin L, Craft TP, Herrbrich PE, Hohm SA, Lahey R, Eades WC, Creer MH, Nolta JA.

Blood. 2006 Mar 1;107(5):2162-9.

7.

Improved purification of hematopoietic stem cells based on their elevated aldehyde dehydrogenase activity.

Christ O, Lucke K, Imren S, Leung K, Hamilton M, Eaves A, Smith C, Eaves C.

Haematologica. 2007 Sep;92(9):1165-72.

8.

Regulation of human hematopoietic stem cell self-renewal by the microenvironment's control of retinoic acid signaling.

Ghiaur G, Yegnasubramanian S, Perkins B, Gucwa JL, Gerber JM, Jones RJ.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16121-6. doi: 10.1073/pnas.1305937110.

9.

RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation.

Purton LE, Dworkin S, Olsen GH, Walkley CR, Fabb SA, Collins SJ, Chambon P.

J Exp Med. 2006 May 15;203(5):1283-93. Erratum in: J Exp Med. 2006 Jun 12;203(6):1615.

10.

Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture.

Safi R, Muramoto GG, Salter AB, Meadows S, Himburg H, Russell L, Daher P, Doan P, Leibowitz MD, Chao NJ, McDonnell DP, Chute JP.

Mol Endocrinol. 2009 Feb;23(2):188-201. doi: 10.1210/me.2008-0121.

11.

IFN-gamma negatively modulates self-renewal of repopulating human hemopoietic stem cells.

Yang L, Dybedal I, Bryder D, Nilsson L, Sitnicka E, Sasaki Y, Jacobsen SE.

J Immunol. 2005 Jan 15;174(2):752-7.

12.

Clonal analysis of thymus-repopulating cells presents direct evidence for self-renewal division of human hematopoietic stem cells.

Yahata T, Yumino S, Seng Y, Miyatake H, Uno T, Muguruma Y, Ito M, Miyoshi H, Kato S, Hotta T, Ando K.

Blood. 2006 Oct 1;108(7):2446-54.

13.

Expansion of human SCID-repopulating cells under hypoxic conditions.

Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC.

J Clin Invest. 2003 Jul;112(1):126-35.

14.
15.

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction.

Seita J, Ema H, Ooehara J, Yamazaki S, Tadokoro Y, Yamasaki A, Eto K, Takaki S, Takatsu K, Nakauchi H.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2349-54.

16.
17.

Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin-CD34+CD38- population.

McKenzie JL, Takenaka K, Gan OI, Doedens M, Dick JE.

Blood. 2007 Jan 15;109(2):543-5.

18.

Long-term expansion of transplantable human fetal liver hematopoietic stem cells.

Rollini P, Kaiser S, Faes-van't Hull E, Kapp U, Leyvraz S.

Blood. 2004 Feb 1;103(3):1166-70.

19.

The HOXB4 homeoprotein differentially promotes ex vivo expansion of early human lymphoid progenitors.

Haddad R, Pflumio F, Vigon I, Visentin G, Auvray C, Fichelson S, Amsellem S.

Stem Cells. 2008 Feb;26(2):312-22.

20.

Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44⁺ human breast cancer cells.

Croker AK, Allan AL.

Breast Cancer Res Treat. 2012 May;133(1):75-87. doi: 10.1007/s10549-011-1692-y.

PMID:
21818590
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