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Items: 1 to 20 of 188

1.

Ozonolysis applications in drug synthesis.

Van Ornum SG, Champeau RM, Pariza R.

Chem Rev. 2006 Jul;106(7):2990-3001. Review. No abstract available.

PMID:
16836306
2.

Asymmetric synthesis of active pharmaceutical ingredients.

Farina V, Reeves JT, Senanayake CH, Song JJ.

Chem Rev. 2006 Jul;106(7):2734-93. Review. No abstract available.

PMID:
16836298
3.

Boron reagents in process chemistry: Excellent tools for selective reductions.

Burkhardt ER, Matos K.

Chem Rev. 2006 Jul;106(7):2617-50. Review. No abstract available.

PMID:
16836295
4.

The impact of microwave synthesis on drug discovery.

Kappe CO, Dallinger D.

Nat Rev Drug Discov. 2006 Jan;5(1):51-63. Review.

PMID:
16374514
5.

Large-scale oxidations in the pharmaceutical industry.

Caron S, Dugger RW, Ruggeri SG, Ragan JA, Ripin DH.

Chem Rev. 2006 Jul;106(7):2943-89. Review. No abstract available.

PMID:
16836305
6.

Aseptic processing of protein pharmaceuticals.

Townsend M.

Pharm Biotechnol. 2002;14:129-89. Review. No abstract available.

PMID:
12189724
7.

Synthesis of chiral building blocks for use in drug discovery.

Marino ST, Stachurska-Buczek D, Huggins DA, Krywult BM, Sheehan CS, Nguyen T, Choi N, Parsons JG, Griffiths PG, James IW, Bray AM, White JM, Boyce RS.

Molecules. 2004 May 31;9(6):405-26.

8.

Organolithium reagents in pharmaceutical asymmetric processes.

Wu G, Huang M.

Chem Rev. 2006 Jul;106(7):2596-616. Review. No abstract available.

PMID:
16836294
9.

Accelerating the drug-discovery process: new tools and technologies available to medicinal chemists.

Raveglia LF, Giardina GA.

Future Med Chem. 2009 Sep;1(6):1019-23. doi: 10.4155/fmc.09.79. No abstract available.

10.

Random molecular fragment methods in computational medicinal chemistry.

Lounkine E, Batista J, Bajorath J.

Curr Med Chem. 2008;15(21):2108-21. Review.

PMID:
18781938
11.

Critical assessment of pharmaceutical processes--A rationale for changing the synthetic route.

Butters M, Catterick D, Craig A, Curzons A, Dale D, Gillmore A, Green SP, Marziano I, Sherlock JP, White W.

Chem Rev. 2006 Jul;106(7):3002-27. Review. No abstract available.

PMID:
16836307
12.

Applications of the combination of microwave and parallel synthesis in medicinal chemistry.

Alcázar J, Dielsb G, Schoentjes B.

Comb Chem High Throughput Screen. 2007 Dec;10(10):918-32. Review.

PMID:
18288951
13.

March of the synthesis machines.

Sanderson K.

Nat Rev Drug Discov. 2015 May;14(5):299-300. doi: 10.1038/nrd4613. No abstract available.

PMID:
25924572
14.

Stereoselective heterocycle synthesis through oxidative carbon-hydrogen bond activation.

Liu L, Floreancig PE.

Curr Opin Drug Discov Devel. 2010;13(6):733-47. Review.

PMID:
21061234
15.

Enabling continuous-flow chemistry in microstructured devices for pharmaceutical and fine-chemical production.

Kockmann N, Gottsponer M, Zimmermann B, Roberge DM.

Chemistry. 2008;14(25):7470-7. doi: 10.1002/chem.200800707.

PMID:
18613163
16.

Selective growth of a stable drug polymorph by suppressing the nucleation of corresponding metastable polymorphs.

Cox JR, Ferris LA, Thalladi VR.

Angew Chem Int Ed Engl. 2007;46(23):4333-6. No abstract available.

PMID:
17476660
17.

Practical methodologies for the synthesis of indoles.

Humphrey GR, Kuethe JT.

Chem Rev. 2006 Jul;106(7):2875-911. Review. No abstract available.

PMID:
16836303
18.

Expanding the scope of crystal form evaluation in pharmaceutical science.

Peterson ML, Hickey MB, Zaworotko MJ, Almarsson O.

J Pharm Pharm Sci. 2006;9(3):317-26. Review.

19.

Diversity-oriented synthesis.

Spandl RJ, Díaz-Gavilán M, O'Connell KM, Thomas GL, Spring DR.

Chem Rec. 2008;8(3):129-42. doi: 10.1002/tcr.20144.

PMID:
18563806
20.

[An advancement in drug research: rational drug design with combinatorial chemistry].

Pindur U.

Pharm Unserer Zeit. 1997 Jan;26(1):24-30. Review. German. No abstract available. Erratum in: Pharm Unserer Zeit 1997 Mar;26(2):112.

PMID:
9157462

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