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Items: 1 to 20 of 93


Longitudinal assessment of de novo T cell production in relation to HIV-associated T cell homeostasis failure.

Chattopadhyay PK, Douek DC, Gange SJ, Chadwick KR, Hellerstein M, Margolick JB.

AIDS Res Hum Retroviruses. 2006 Jun;22(6):501-7.


HIV-infected long-term nonprogressors display a unique correlative pattern between the interleukin-7/interleukin-7 receptor circuit and T-cell homeostasis.

Marchetti G, Riva A, Cesari M, Bellistrì GM, Gianelli E, Casabianca A, Orlandi C, Magnani M, Meroni L, d'Arminio Monforte A, Mussini C, Cossarizza A, Galli M, Gori A; Elvis Study Group.

HIV Med. 2009 Aug;10(7):422-31. doi: 10.1111/j.1468-1293.2009.00710.x. Epub 2009 May 5.


Altered naive CD4 and CD8 T cell homeostasis in patients with relapsing-remitting multiple sclerosis: thymic versus peripheral (non-thymic) mechanisms.

Duszczyszyn DA, Beck JD, Antel J, Bar-Or A, Lapierre Y, Gadag V, Haegert DG.

Clin Exp Immunol. 2006 Feb;143(2):305-13.


IL-2 therapy and thymic production of naive CD4 T cells in HIV-infected patients with severe CD4 lymphopenia.

Carcelain G, Saint-Mézard P, Altes HK, Tubiana R, Grenot P, Rabian C, de Boer R, Costagliola D, Katlama C, Debré P, Autran B.

AIDS. 2003 Apr 11;17(6):841-50.


Effect of recent thymic emigrants on progression of HIV-1 disease.

Hatzakis A, Touloumi G, Karanicolas R, Karafoulidou A, Mandalaki T, Anastassopoulou C, Zhang L, Goedert JJ, Ho DD, Kostrikis LG.

Lancet. 2000 Feb 19;355(9204):599-604.


Thymic export function and T cell homeostasis in patients with relapsing remitting multiple sclerosis.

Hug A, Korporal M, Schröder I, Haas J, Glatz K, Storch-Hagenlocher B, Wildemann B.

J Immunol. 2003 Jul 1;171(1):432-7.


T-cell reconstitution after allogeneic stem cell transplantation: assessment by measurement of the sjTREC/βTREC ratio and thymic naive T cells.

Ringhoffer S, Rojewski M, Döhner H, Bunjes D, Ringhoffer M.

Haematologica. 2013 Oct;98(10):1600-8. doi: 10.3324/haematol.2012.072264. Epub 2013 Apr 12.


Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection.

Hazenberg MD, Otto SA, Cohen Stuart JW, Verschuren MC, Borleffs JC, Boucher CA, Coutinho RA, Lange JM, Rinke de Wit TF, Tsegaye A, van Dongen JJ, Hamann D, de Boer RJ, Miedema F.

Nat Med. 2000 Sep;6(9):1036-42.


Identification of inflections in T-cell counts among HIV-1-infected individuals and relationship with progression to clinical AIDS.

Gange SJ, Muñoz A, Chmiel JS, Donnenberg AD, Kirstein LM, Detels R, Margolick JB.

Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10848-53.


T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals.

Steffens CM, Smith KY, Landay A, Shott S, Truckenbrod A, Russert M, Al-Harthi L.

AIDS. 2001 Sep 28;15(14):1757-64.


Recent thymic emigrants in lymphoma patients with and without human immunodeficiency virus infection candidates for autologous peripheral stem cell transplantation.

Pratesi C, Simonelli C, Zanussi S, Talamini R, Bortolin MT, Tedeschi R, Marus A, Caffau C, Michieli M, Tirelli U, De Paoli P.

Clin Exp Immunol. 2008 Jan;151(1):101-9. Epub 2007 Oct 11.


Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection.

Sasson SC, Zaunders JJ, Seddiki N, Bailey M, McBride K, Koelsch KK, Merlin KM, Smith DE, Cooper DA, Kelleher AD.

PLoS One. 2012;7(2):e31148. doi: 10.1371/journal.pone.0031148. Epub 2012 Feb 13.


Analysis of telomere length and thymic output in fast and slow/non-progressors with HIV infection.

Richardson MW, Sverstiuk A, Hendel H, Cheung TW, Zagury JF, Rappaport J.

Biomed Pharmacother. 2000 Feb;54(1):21-31.


Evidence for increased T cell turnover and decreased thymic output in HIV infection.

Douek DC, Betts MR, Hill BJ, Little SJ, Lempicki R, Metcalf JA, Casazza J, Yoder C, Adelsberger JW, Stevens RA, Baseler MW, Keiser P, Richman DD, Davey RT, Koup RA.

J Immunol. 2001 Dec 1;167(11):6663-8.


Increased levels of regulatory T cells (Tregs) in human immunodeficiency virus-infected patients after 5 years of highly active anti-retroviral therapy may be due to increased thymic production of naive Tregs.

Kolte L, Gaardbo JC, Skogstrand K, Ryder LP, Ersbøll AK, Nielsen SD.

Clin Exp Immunol. 2009 Jan;155(1):44-52. doi: 10.1111/j.1365-2249.2008.03803.x. Epub 2008 Nov 6.


Excessive conversion and impaired thymic output contribute to disturbed regulatory T-cell homeostasis in AIDS patients with low CD4 cell counts.

Zhou H, Zhao H, Hao Y, Song C, Han J, Zhang J, Gao G, Han N, Yang D, Li Y, Zhang F, Zeng H.

AIDS. 2013 Apr 24;27(7):1059-69. doi: 10.1097/QAD.0b013e32835e2b99.


Anti-HIV type 1 memory cytotoxic T lymphocyte responses associated with changes in CD4+ T cell numbers in progression of HIV type 1 infection.

Rinaldo CR Jr, Gupta P, Huang XL, Fan Z, Mullins JI, Gange S, Farzadegan H, Shankarappa R, Muñoz A, Margolick JB.

AIDS Res Hum Retroviruses. 1998 Nov 1;14(16):1423-33.


The contribution of the thymus to the recovery of peripheral naive T-cell numbers during antiretroviral treatment for HIV infection.

Ribeiro RM, de Boer RJ.

J Acquir Immune Defic Syndr. 2008 Sep 1;49(1):1-8. doi: 10.1097/QAI.0b013e318184fb28.


Clinical impact of altered T-cell homeostasis in treated HIV patients enrolled in a large observational cohort.

Ndumbi P, Gillis J, Raboud JM, Cooper C, Hogg RS, Montaner JS, Burchell AN, Loutfy MR, Machouf N, Klein MB, Tsoukas CM; Canadian Observational Cohort (CANOC) collaboration.

AIDS. 2013 Nov 28;27(18):2863-72. doi: 10.1097/01.aids.0000432471.84497.bc.


Strong association between failure of T cell homeostasis and the syncytium-inducing phenotype among HIV-1-infected men in the Amsterdam Cohort Study.

Maas JJ, Gange SJ, Schuitemaker H, Coutinho RA, van Leeuwen R, Margolick JB.

AIDS. 2000 Jun 16;14(9):1155-61.


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