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Thiazolidinediones prevent PDGF-BB-induced CREB depletion in pulmonary artery smooth muscle cells by preventing upregulation of casein kinase 2 alpha' catalytic subunit.

Garat CV, Crossno JT Jr, Sullivan TM, Reusch JE, Klemm DJ.

J Cardiovasc Pharmacol. 2010 May;55(5):469-80. doi: 10.1097/FJC.0b013e3181d64dbe.


Synergistic roles of platelet-derived growth factor-BB and interleukin-1beta in phenotypic modulation of human aortic smooth muscle cells.

Chen CN, Li YS, Yeh YT, Lee PL, Usami S, Chien S, Chiu JJ.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2665-70. Epub 2006 Feb 13.


Inhibition of phosphatidylinositol 3-kinase/Akt signaling attenuates hypoxia-induced pulmonary artery remodeling and suppresses CREB depletion in arterial smooth muscle cells.

Garat CV, Crossno JT Jr, Sullivan TM, Reusch JE, Klemm DJ.

J Cardiovasc Pharmacol. 2013 Dec;62(6):539-48. doi: 10.1097/FJC.0000000000000014.


Autocrine expression of osteopontin contributes to PDGF-mediated arterial smooth muscle cell migration.

Jalvy S, Renault MA, Leen LL, Belloc I, Bonnet J, Gadeau AP, Desgranges C.

Cardiovasc Res. 2007 Sep 1;75(4):738-47. Epub 2007 May 24.


Chronic treatment with PDGF-BB and endothelin-1 synergistically induces vascular hyperplasia and loss of contractility in organ-cultured rat tail artery.

Kida T, Chuma H, Murata T, Yamawaki H, Matsumoto S, Hori M, Ozaki H.

Atherosclerosis. 2011 Feb;214(2):288-94. doi: 10.1016/j.atherosclerosis.2010.11.001. Epub 2010 Nov 11.


Calpain-2 activates Akt via TGF-β1-mTORC2 pathway in pulmonary artery smooth muscle cells.

Abeyrathna P, Kovacs L, Han W, Su Y.

Am J Physiol Cell Physiol. 2016 Jul 1;311(1):C24-34. doi: 10.1152/ajpcell.00295.2015. Epub 2016 Apr 20.


Reduction of reactive oxygen species prevents hypoxia-induced CREB depletion in pulmonary artery smooth muscle cells.

Klemm DJ, Majka SM, Crossno JT Jr, Psilas JC, Reusch JE, Garat CV.

J Cardiovasc Pharmacol. 2011 Aug;58(2):181-91. doi: 10.1097/FJC.0b013e31821f2773.


Signaling through PI3K/Akt mediates stretch and PDGF-BB-dependent DNA synthesis in bladder smooth muscle cells.

Adam RM, Roth JA, Cheng HL, Rice DC, Khoury J, Bauer SB, Peters CA, Freeman MR.

J Urol. 2003 Jun;169(6):2388-93.


Sodium butyrate inhibits platelet-derived growth factor-induced proliferation of vascular smooth muscle cells.

Ranganna K, Joshi T, Yatsu FM.

Arterioscler Thromb Vasc Biol. 1995 Dec;15(12):2273-83.


Platelet-derived growth factor induces tissue factor expression in vascular smooth muscle cells via activation of Egr-1.

Kamimura M, Bea F, Akizawa T, Katus HA, Kreuzer J, Viedt C.

Hypertension. 2004 Dec;44(6):944-51. Epub 2004 Oct 18.


Platelet-derived growth factor-BB-induced human smooth muscle cell proliferation depends on basic FGF release and FGFR-1 activation.

Millette E, Rauch BH, Defawe O, Kenagy RD, Daum G, Clowes AW.

Circ Res. 2005 Feb 4;96(2):172-9. Epub 2004 Dec 29.


PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.

Zhao Y, Biswas SK, McNulty PH, Kozak M, Jun JY, Segar L.

Am J Physiol Cell Physiol. 2011 Jun;300(6):C1375-85. doi: 10.1152/ajpcell.00670.2008. Epub 2011 Feb 16.


Serotonin transporter interacts with the PDGFβ receptor in PDGF-BB-induced signaling and mitogenesis in pulmonary artery smooth muscle cells.

Ren W, Watts SW, Fanburg BL.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L486-97. doi: 10.1152/ajplung.00237.2010. Epub 2010 Dec 24.


PDGF Promotes the Warburg Effect in Pulmonary Arterial Smooth Muscle Cells via Activation of the PI3K/AKT/mTOR/HIF-1α Signaling Pathway.

Xiao Y, Peng H, Hong C, Chen Z, Deng X, Wang A, Yang F, Yang L, Chen C, Qin X.

Cell Physiol Biochem. 2017;42(4):1603-1613. doi: 10.1159/000479401. Epub 2017 Jul 24.


Prevention of vascular smooth muscle cell proliferation and injury-induced neointimal hyperplasia by CREB-mediated p21 induction: An insight from a plant polyphenol.

Sun L, Zhao R, Zhang L, Zhang W, He G, Yang S, Song J, Du G.

Biochem Pharmacol. 2016 Mar 1;103:40-52. doi: 10.1016/j.bcp.2016.01.015. Epub 2016 Jan 22.


Ets-1 mediates platelet-derived growth factor-BB-induced thrombomodulin expression in human vascular smooth muscle cells.

Lo IC, Lin TM, Chou LH, Liu SL, Wu LW, Shi GY, Wu HL, Jiang MJ.

Cardiovasc Res. 2009 Mar 1;81(4):771-9. doi: 10.1093/cvr/cvn351. Epub 2008 Dec 17.


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