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Items: 1 to 20 of 140

1.

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1.

Ishihara N, Fujita Y, Oka T, Mihara K.

EMBO J. 2006 Jul 12;25(13):2966-77.

2.

OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria.

Duvezin-Caubet S, Koppen M, Wagener J, Zick M, Israel L, Bernacchia A, Jagasia R, Rugarli EI, Imhof A, Neupert W, Langer T, Reichert AS.

Mol Biol Cell. 2007 Sep;18(9):3582-90.

3.

Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA.

Herlan M, Vogel F, Bornhovd C, Neupert W, Reichert AS.

J Biol Chem. 2003 Jul 25;278(30):27781-8.

4.

Characterization of OPA1 isoforms isolated from mouse tissues.

Akepati VR, Müller EC, Otto A, Strauss HM, Portwich M, Alexander C.

J Neurochem. 2008 Jul;106(1):372-83. doi: 10.1111/j.1471-4159.2008.05401.x.

5.

Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1.

Ehses S, Raschke I, Mancuso G, Bernacchia A, Geimer S, Tondera D, Martinou JC, Westermann B, Rugarli EI, Langer T.

J Cell Biol. 2009 Dec 28;187(7):1023-36. doi: 10.1083/jcb.200906084.

6.

Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology.

Duvezin-Caubet S, Jagasia R, Wagener J, Hofmann S, Trifunovic A, Hansson A, Chomyn A, Bauer MF, Attardi G, Larsson NG, Neupert W, Reichert AS.

J Biol Chem. 2006 Dec 8;281(49):37972-9.

7.

Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage.

Griparic L, Kanazawa T, van der Bliek AM.

J Cell Biol. 2007 Aug 27;178(5):757-64.

8.

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

Song Z, Chen H, Fiket M, Alexander C, Chan DC.

J Cell Biol. 2007 Aug 27;178(5):749-55.

9.

Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria.

Satoh M, Hamamoto T, Seo N, Kagawa Y, Endo H.

Biochem Biophys Res Commun. 2003 Jan 10;300(2):482-93.

PMID:
12504110
10.

Metalloprotease-mediated OPA1 processing is modulated by the mitochondrial membrane potential.

Guillery O, Malka F, Landes T, Guillou E, Blackstone C, Lombès A, Belenguer P, Arnoult D, Rojo M.

Biol Cell. 2008 May;100(5):315-25.

PMID:
18076378
11.

Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria.

Griparic L, van der Wel NN, Orozco IJ, Peters PJ, van der Bliek AM.

J Biol Chem. 2004 Apr 30;279(18):18792-8.

12.

Loss of Drp1 function alters OPA1 processing and changes mitochondrial membrane organization.

Möpert K, Hajek P, Frank S, Chen C, Kaufmann J, Santel A.

Exp Cell Res. 2009 Aug 1;315(13):2165-80. doi: 10.1016/j.yexcr.2009.04.016.

PMID:
19409380
13.

OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals.

Baricault L, Ségui B, Guégand L, Olichon A, Valette A, Larminat F, Lenaers G.

Exp Cell Res. 2007 Oct 15;313(17):3800-8.

PMID:
17826766
14.

Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis.

Olichon A, Landes T, Arnauné-Pelloquin L, Emorine LJ, Mils V, Guichet A, Delettre C, Hamel C, Amati-Bonneau P, Bonneau D, Reynier P, Lenaers G, Belenguer P.

J Cell Physiol. 2007 May;211(2):423-30.

PMID:
17167772
15.

OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis.

Olichon A, Elachouri G, Baricault L, Delettre C, Belenguer P, Lenaers G.

Cell Death Differ. 2007 Apr;14(4):682-92.

16.

Distinct roles of the two isoforms of the dynamin-like GTPase Mgm1 in mitochondrial fusion.

Zick M, Duvezin-Caubet S, Schäfer A, Vogel F, Neupert W, Reichert AS.

FEBS Lett. 2009 Jul 7;583(13):2237-43. doi: 10.1016/j.febslet.2009.05.053.

17.

Expression of the Opa1 mitochondrial protein in retinal ganglion cells: its downregulation causes aggregation of the mitochondrial network.

Kamei S, Chen-Kuo-Chang M, Cazevieille C, Lenaers G, Olichon A, Bélenguer P, Roussignol G, Renard N, Eybalin M, Michelin A, Delettre C, Brabet P, Hamel CP.

Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4288-94.

PMID:
16249510
18.

Regulation of mitochondrial morphology by membrane potential, and DRP1-dependent division and FZO1-dependent fusion reaction in mammalian cells.

Ishihara N, Jofuku A, Eura Y, Mihara K.

Biochem Biophys Res Commun. 2003 Feb 21;301(4):891-8.

PMID:
12589796
19.

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis.

Olichon A, Baricault L, Gas N, Guillou E, Valette A, Belenguer P, Lenaers G.

J Biol Chem. 2003 Mar 7;278(10):7743-6.

20.

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.

Anand R, Wai T, Baker MJ, Kladt N, Schauss AC, Rugarli E, Langer T.

J Cell Biol. 2014 Mar 17;204(6):919-29. doi: 10.1083/jcb.201308006.

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