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Items: 1 to 20 of 155

1.

Signal peptide peptidase is required for dislocation from the endoplasmic reticulum.

Loureiro J, Lilley BN, Spooner E, Noriega V, Tortorella D, Ploegh HL.

Nature. 2006 Jun 15;441(7095):894-7. Epub 2006 May 31.

PMID:
16738546
2.

TRAM1 participates in human cytomegalovirus US2- and US11-mediated dislocation of an endoplasmic reticulum membrane glycoprotein.

Oresic K, Ng CL, Tortorella D.

J Biol Chem. 2009 Feb 27;284(9):5905-14. doi: 10.1074/jbc.M807568200. Epub 2009 Jan 2.

3.
4.

Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum.

Furman MH, Loureiro J, Ploegh HL, Tortorella D.

J Biol Chem. 2003 Sep 12;278(37):34804-11. Epub 2003 Jun 27.

5.

Subtle sequence variation among MHC class I locus products greatly influences sensitivity to HCMV US2- and US11-mediated degradation.

Barel MT, Pizzato N, Le Bouteiller P, Wiertz EJ, Lenfant F.

Int Immunol. 2006 Jan;18(1):173-82. Epub 2005 Dec 16.

PMID:
16361314
6.

Human cytomegalovirus-encoded US2 and US11 target unassembled MHC class I heavy chains for degradation.

Barel MT, Hassink GC, van Voorden S, Wiertz EJ.

Mol Immunol. 2006 Mar;43(8):1258-66. Epub 2005 Aug 10.

PMID:
16098592
7.

Human cytomegalovirus gene products US2 and US11 differ in their ability to attack major histocompatibility class I heavy chains in dendritic cells.

Rehm A, Engelsberg A, Tortorella D, Körner IJ, Lehmann I, Ploegh HL, Höpken UE.

J Virol. 2002 May;76(10):5043-50.

8.

Human cytomegalovirus-encoded US2 differentially affects surface expression of MHC class I locus products and targets membrane-bound, but not soluble HLA-G1 for degradation.

Barel MT, Ressing M, Pizzato N, van Leeuwen D, Le Bouteiller P, Lenfant F, Wiertz EJ.

J Immunol. 2003 Dec 15;171(12):6757-65.

9.

Ubiquitination of MHC class I heavy chains is essential for dislocation by human cytomegalovirus-encoded US2 but not US11.

Hassink GC, Barel MT, Van Voorden SB, Kikkert M, Wiertz EJ.

J Biol Chem. 2006 Oct 6;281(40):30063-71. Epub 2006 Jul 29.

10.

A membrane protein required for dislocation of misfolded proteins from the ER.

Lilley BN, Ploegh HL.

Nature. 2004 Jun 24;429(6994):834-40.

11.

Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation.

Lee SO, Cho K, Cho S, Kim I, Oh C, Ahn K.

EMBO J. 2010 Jan 20;29(2):363-75. doi: 10.1038/emboj.2009.359. Epub 2009 Nov 26.

12.

The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins.

Hegde NR, Chevalier MS, Wisner TW, Denton MC, Shire K, Frappier L, Johnson DC.

J Biol Chem. 2006 Jul 28;281(30):20910-9. Epub 2006 May 25.

13.

Functional dissection of HCMV US11 in mediating the degradation of MHC class I molecules.

Lee SO, Hwang S, Park J, Park B, Jin BS, Lee S, Kim E, Cho S, Kim Y, Cho K, Shin J, Ahn K.

Biochem Biophys Res Commun. 2005 May 20;330(4):1262-7.

PMID:
15823579
14.
15.

Binding of human cytomegalovirus US2 to major histocompatibility complex class I and II proteins is not sufficient for their degradation.

Chevalier MS, Daniels GM, Johnson DC.

J Virol. 2002 Aug;76(16):8265-75. Erratum in: J Virol 2002 Dec;76(24):13126.

16.
17.

A structural determinant of human cytomegalovirus US2 dictates the down-regulation of class I major histocompatibility molecules.

Oresic K, Noriega V, Andrews L, Tortorella D.

J Biol Chem. 2006 Jul 14;281(28):19395-406. Epub 2006 May 10.

18.
19.

The HCMV gene products US2 and US11 target MHC class I molecules for degradation in the cytosol.

van der Wal FJ, Kikkert M, Wiertz E.

Curr Top Microbiol Immunol. 2002;269:37-55. Review.

PMID:
12224515
20.

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