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Items: 1 to 20 of 126

1.

Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage.

Wang H, Zhai L, Xu J, Joo HY, Jackson S, Erdjument-Bromage H, Tempst P, Xiong Y, Zhang Y.

Mol Cell. 2006 May 5;22(3):383-94.

2.

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.

Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H.

Nat Cell Biol. 2006 Nov;8(11):1277-83. Epub 2006 Oct 15.

PMID:
17041588
3.

The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A.

Guerrero-Santoro J, Kapetanaki MG, Hsieh CL, Gorbachinsky I, Levine AS, Rapić-Otrin V.

Cancer Res. 2008 Jul 1;68(13):5014-22. doi: 10.1158/0008-5472.CAN-07-6162.

4.

A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly.

Han J, Zhang H, Zhang H, Wang Z, Zhou H, Zhang Z.

Cell. 2013 Nov 7;155(4):817-29. doi: 10.1016/j.cell.2013.10.014.

5.

The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites.

Kapetanaki MG, Guerrero-Santoro J, Bisi DC, Hsieh CL, Rapić-Otrin V, Levine AS.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2588-93. Epub 2006 Feb 10.

6.

DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.

Takedachi A, Saijo M, Tanaka K.

Mol Cell Biol. 2010 Jun;30(11):2708-23. doi: 10.1128/MCB.01460-09. Epub 2010 Apr 5.

7.

Ubiquitin proteasome system (UPS): what can chromatin do for you?

O'Connell BC, Harper JW.

Curr Opin Cell Biol. 2007 Apr;19(2):206-14. Epub 2007 Feb 20. Review.

PMID:
17314036
8.

DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity.

Li J, Wang QE, Zhu Q, El-Mahdy MA, Wani G, Praetorius-Ibba M, Wani AA.

Cancer Res. 2006 Sep 1;66(17):8590-7.

9.

UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex.

Sugasawa K, Okuda Y, Saijo M, Nishi R, Matsuda N, Chu G, Mori T, Iwai S, Tanaka K, Tanaka K, Hanaoka F.

Cell. 2005 May 6;121(3):387-400.

10.

DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex.

Matsuda N, Azuma K, Saijo M, Iemura S, Hioki Y, Natsume T, Chiba T, Tanaka K, Tanaka K.

DNA Repair (Amst). 2005 May 2;4(5):537-45.

PMID:
15811626
11.

CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10.

Kaur M, Khan MM, Kar A, Sharma A, Saxena S.

Nucleic Acids Res. 2012 Aug;40(15):7332-46. doi: 10.1093/nar/gks366. Epub 2012 May 8.

12.

UV-induced ubiquitylation of XPC complex, the UV-DDB-ubiquitin ligase complex, and DNA repair.

Sugasawa K.

J Mol Histol. 2006 Sep;37(5-7):189-202. Epub 2006 Jul 21. Review.

PMID:
16858626
13.

L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes.

Banks D, Wu M, Higa LA, Gavrilova N, Quan J, Ye T, Kobayashi R, Sun H, Zhang H.

Cell Cycle. 2006 Aug;5(15):1719-29. Epub 2006 Aug 1.

PMID:
16861890
14.

Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNA.

Fei J, Kaczmarek N, Luch A, Glas A, Carell T, Naegeli H.

PLoS Biol. 2011 Oct;9(10):e1001183. doi: 10.1371/journal.pbio.1001183. Epub 2011 Oct 25.

15.

"Cullin 4 makes its mark on chromatin".

Dai Q, Wang H.

Cell Div. 2006 Jul 10;1:14.

16.

Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage.

Hu J, McCall CM, Ohta T, Xiong Y.

Nat Cell Biol. 2004 Oct;6(10):1003-9. Epub 2004 Sep 26.

PMID:
15448697
17.

WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.

Hu J, Zacharek S, He YJ, Lee H, Shumway S, Duronio RJ, Xiong Y.

Genes Dev. 2008 Apr 1;22(7):866-71. doi: 10.1101/gad.1624008.

18.

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.

Angers S, Li T, Yi X, MacCoss MJ, Moon RT, Zheng N.

Nature. 2006 Oct 5;443(7111):590-3.

PMID:
16964240
19.

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

Groisman R, Polanowska J, Kuraoka I, Sawada J, Saijo M, Drapkin R, Kisselev AF, Tanaka K, Nakatani Y.

Cell. 2003 May 2;113(3):357-67.

20.

Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC.

El-Mahdy MA, Zhu Q, Wang QE, Wani G, Praetorius-Ibba M, Wani AA.

J Biol Chem. 2006 May 12;281(19):13404-11. Epub 2006 Mar 8.

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