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Items: 1 to 20 of 132

1.

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf.

Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, Aderem A.

Nat Immunol. 2006 Jun;7(6):569-75. Epub 2006 Apr 30.

PMID:
16648853
2.

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages.

Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozören N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Núñez G.

Nat Immunol. 2006 Jun;7(6):576-82. Epub 2006 Apr 30.

PMID:
16648852
3.

Injection of flagellin into the host cell cytosol by Salmonella enterica serotype Typhimurium.

Sun YH, Rolán HG, Tsolis RM.

J Biol Chem. 2007 Nov 23;282(47):33897-901. Epub 2007 Oct 1.

4.

Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation.

Franchi L, Stoolman J, Kanneganti TD, Verma A, Ramphal R, Núñez G.

Eur J Immunol. 2007 Nov;37(11):3030-9.

5.

Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.

Franchi L, Kanneganti TD, Dubyak GR, Núñez G.

J Biol Chem. 2007 Jun 29;282(26):18810-8. Epub 2007 May 9.

6.

The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation.

Lamkanfi M, Amer A, Kanneganti TD, Muñoz-Planillo R, Chen G, Vandenabeele P, Fortier A, Gros P, Núñez G.

J Immunol. 2007 Jun 15;178(12):8022-7.

7.

TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system.

Miao EA, Andersen-Nissen E, Warren SE, Aderem A.

Semin Immunopathol. 2007 Sep;29(3):275-88. Epub 2007 Aug 10. Review.

PMID:
17690885
8.
9.

Flagellin expression enhances Salmonella accumulation in TLR5-positive macrophages.

Metcalfe HJ, Best A, Kanellos T, La Ragione RM, Werling D.

Dev Comp Immunol. 2010 Aug;34(8):797-804. doi: 10.1016/j.dci.2010.02.008. Epub 2010 Mar 4.

PMID:
20188752
10.

Pseudomonas aeruginosa activates caspase 1 through Ipaf.

Miao EA, Ernst RK, Dors M, Mao DP, Aderem A.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2562-7. doi: 10.1073/pnas.0712183105. Epub 2008 Feb 6.

11.

Involvement of caspase 1 and its activator Ipaf upstream of mitochondrial events in apoptosis.

Thalappilly S, Sadasivam S, Radha V, Swarup G.

FEBS J. 2006 Jun;273(12):2766-78.

13.

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella.

Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM.

J Exp Med. 2010 Aug 2;207(8):1745-55. doi: 10.1084/jem.20100257. Epub 2010 Jul 5.

14.

Salmonella downregulates Nod-like receptor family CARD domain containing protein 4 expression to promote its survival in B cells by preventing inflammasome activation and cell death.

Perez-Lopez A, Rosales-Reyes R, Alpuche-Aranda CM, Ortiz-Navarrete V.

J Immunol. 2013 Feb 1;190(3):1201-9. doi: 10.4049/jimmunol.1200415. Epub 2013 Jan 2.

15.

Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis.

Silveira TN, Zamboni DS.

Infect Immun. 2010 Mar;78(3):1403-13. doi: 10.1128/IAI.00905-09. Epub 2010 Jan 4.

16.

Flagellin is the major proinflammatory determinant of enteropathogenic Salmonella.

Zeng H, Carlson AQ, Guo Y, Yu Y, Collier-Hyams LS, Madara JL, Gewirtz AT, Neish AS.

J Immunol. 2003 Oct 1;171(7):3668-74.

17.

Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway.

Lyons S, Wang L, Casanova JE, Sitaraman SV, Merlin D, Gewirtz AT.

J Cell Sci. 2004 Nov 15;117(Pt 24):5771-80. Epub 2004 Oct 26.

18.

Lysophospholipid sensing triggers secretion of flagellin from pathogenic salmonella.

Subramanian N, Qadri A.

Nat Immunol. 2006 Jun;7(6):583-9. Epub 2006 Apr 30.

PMID:
16648855
19.

Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf.

Amer A, Franchi L, Kanneganti TD, Body-Malapel M, Ozören N, Brady G, Meshinchi S, Jagirdar R, Gewirtz A, Akira S, Núñez G.

J Biol Chem. 2006 Nov 17;281(46):35217-23. Epub 2006 Sep 19.

20.

In macrophages, caspase-1 activation by SopE and the type III secretion system-1 of S. typhimurium can proceed in the absence of flagellin.

Hoffmann C, Galle M, Dilling S, Käppeli R, Müller AJ, Songhet P, Beyaert R, Hardt WD.

PLoS One. 2010 Aug 30;5(8):e12477. doi: 10.1371/journal.pone.0012477.

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