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Items: 1 to 20 of 99

1.

Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes.

Ueki K, Okada T, Hu J, Liew CW, Assmann A, Dahlgren GM, Peters JL, Shackman JG, Zhang M, Artner I, Satin LS, Stein R, Holzenberger M, Kennedy RT, Kahn CR, Kulkarni RN.

Nat Genet. 2006 May;38(5):583-8. Epub 2006 Apr 23.

PMID:
16642022
3.

Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor.

Kitamura T, Kido Y, Nef S, Merenmies J, Parada LF, Accili D.

Mol Cell Biol. 2001 Aug;21(16):5624-30.

4.

Does IGF-I stimulate pancreatic islet cell growth?

Liu JL.

Cell Biochem Biophys. 2007;48(2-3):115-25.

PMID:
17709881
5.

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes.

Fernández AM, Kim JK, Yakar S, Dupont J, Hernandez-Sanchez C, Castle AL, Filmore J, Shulman GI, Le Roith D.

Genes Dev. 2001 Aug 1;15(15):1926-34.

6.

Signaling cross talk between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in pancreatic islet β-cells.

Ma F, Wei Z, Shi C, Gan Y, Lu J, Frank SJ, Balducci J, Huang Y.

Mol Endocrinol. 2011 Dec;25(12):2119-33. doi: 10.1210/me.2011-1052. Epub 2011 Oct 27.

7.

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.

Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA, Kahn CR.

Nat Genet. 2002 May;31(1):111-5. Epub 2002 Apr 1.

PMID:
11923875
8.

Distinct and overlapping functions of insulin and IGF-I receptors.

Nakae J, Kido Y, Accili D.

Endocr Rev. 2001 Dec;22(6):818-35. Review.

PMID:
11739335
9.

Beta-Cell hyperplasia induced by hepatic insulin resistance: role of a liver-pancreas endocrine axis through insulin receptor A isoform.

Escribano O, Guillén C, Nevado C, Gómez-Hernández A, Kahn CR, Benito M.

Diabetes. 2009 Apr;58(4):820-8. doi: 10.2337/db08-0551. Epub 2009 Jan 9.

10.

Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes?

Lingohr MK, Buettner R, Rhodes CJ.

Trends Mol Med. 2002 Aug;8(8):375-84. Review.

PMID:
12127723
11.

Molecular insights into insulin action and secretion.

Rhodes CJ, White MF.

Eur J Clin Invest. 2002 Jun;32 Suppl 3:3-13. Review.

PMID:
12028370
12.

Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.

Hennige AM, Ozcan U, Okada T, Jhala US, Schubert M, White MF, Kulkarni RN.

Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E337-46. Epub 2005 Apr 12.

13.

Expression of IGF-I in pancreatic islets prevents lymphocytic infiltration and protects mice from type 1 diabetes.

Casellas A, Salavert A, Agudo J, Ayuso E, Jimenez V, Moya M, Muñoz S, Franckhauser S, Bosch F.

Diabetes. 2006 Dec;55(12):3246-55.

14.

Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways.

Miele C, Rochford JJ, Filippa N, Giorgetti-Peraldi S, Van Obberghen E.

J Biol Chem. 2000 Jul 14;275(28):21695-702.

15.

Targeted gene mutations define the roles of insulin and IGF-I receptors in mouse embryonic development.

Accili D, Nakae J, Kim JJ, Park BC, Rother KI.

J Pediatr Endocrinol Metab. 1999 Jul-Aug;12(4):475-85. Review.

PMID:
10417963
16.

Ras-GRF1 signaling is required for normal beta-cell development and glucose homeostasis.

Font de Mora J, Esteban LM, Burks DJ, Núñez A, Garcés C, García-Barrado MJ, Iglesias-Osma MC, Moratinos J, Ward JM, Santos E.

EMBO J. 2003 Jun 16;22(12):3039-49.

17.

A general and islet cell-enriched overexpression of IGF-I results in normal islet cell growth, hypoglycemia, and significant resistance to experimental diabetes.

Robertson K, Lu Y, De Jesus K, Li B, Su Q, Lund PK, Liu JL.

Am J Physiol Endocrinol Metab. 2008 May;294(5):E928-38. doi: 10.1152/ajpendo.00606.2007. Epub 2008 Feb 12.

18.

Insulin receptor substrate proteins and neuroendocrine function.

Withers DJ.

Biochem Soc Trans. 2001 Aug;29(Pt 4):525-9. Review.

PMID:
11498021
19.
20.

Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance.

Tanabe K, Liu Z, Patel S, Doble BW, Li L, Cras-Méneur C, Martinez SC, Welling CM, White MF, Bernal-Mizrachi E, Woodgett JR, Permutt MA.

PLoS Biol. 2008 Feb;6(2):e37. doi: 10.1371/journal.pbio.0060037.

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