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Items: 1 to 20 of 90

1.

A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease.

Tuncman G, Erbay E, Hom X, De Vivo I, Campos H, Rimm EB, Hotamisligil GS.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):6970-5. Epub 2006 Apr 25.

3.

Low-expression variant of fatty acid-binding protein 4 favors reduced manifestations of atherosclerotic disease and increased plaque stability.

Saksi J, Ijäs P, Mäyränpää MI, Nuotio K, Isoviita PM, Tuimala J, Lehtonen-Smeds E, Kaste M, Jula A, Sinisalo J, Nieminen MS, Lokki ML, Perola M, Havulinna AS, Salomaa V, Kettunen J, Jauhiainen M, Kovanen PT, Lindsberg PJ.

Circ Cardiovasc Genet. 2014 Oct;7(5):588-98. doi: 10.1161/CIRCGENETICS.113.000499. Epub 2014 Aug 13.

4.

Human tyrosine hydroxylase natural genetic variation: delineation of functional transcriptional control motifs disrupted in the proximal promoter.

Zhang K, Zhang L, Rao F, Brar B, Rodriguez-Flores JL, Taupenot L, O'Connor DT.

Circ Cardiovasc Genet. 2010 Apr;3(2):187-98. doi: 10.1161/CIRCGENETICS.109.904813. Epub 2010 Feb 2.

5.

Role of the fatty acid binding protein mal1 in obesity and insulin resistance.

Maeda K, Uysal KT, Makowski L, Görgün CZ, Atsumi G, Parker RA, Brüning J, Hertzel AV, Bernlohr DA, Hotamisligil GS.

Diabetes. 2003 Feb;52(2):300-7.

6.

Common genetic variants in fatty acid-binding protein-4 (FABP4) and clinical diabetes risk in the Women's Health Initiative Observational Study.

Chan KH, Song Y, Hsu YH, You NC, F Tinker L, Liu S.

Obesity (Silver Spring). 2010 Sep;18(9):1812-20. doi: 10.1038/oby.2009.496. Epub 2010 Jan 28.

7.

Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals.

Fisher E, Grallert H, Klapper M, Pfäfflin A, Schrezenmeir J, Illig T, Boeing H, Döring F.

Mol Genet Metab. 2009 Dec;98(4):400-5. doi: 10.1016/j.ymgme.2009.08.001. Epub 2009 Aug 11.

PMID:
19744871
8.

A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans.

Krempler F, Esterbauer H, Weitgasser R, Ebenbichler C, Patsch JR, Miller K, Xie M, Linnemayr V, Oberkofler H, Patsch W.

Diabetes. 2002 Nov;51(11):3331-5.

9.

Improved glucose and lipid metabolism in genetically obese mice lacking aP2.

Uysal KT, Scheja L, Wiesbrock SM, Bonner-Weir S, Hotamisligil GS.

Endocrinology. 2000 Sep;141(9):3388-96.

PMID:
10965911
10.

Generation of porcine fibroblasts overexpressing 11β-HSD1 with adipose tissue-specific aP2 promoter as a porcine model of metabolic syndrome.

Jung EM, An BS, Kim YK, Jeong YH, Hwang WS, Jeung EB.

Mol Med Rep. 2013 Sep;8(3):751-6. doi: 10.3892/mmr.2013.1592. Epub 2013 Jul 17.

PMID:
23864280
11.

Relation between human vasopressin 1a gene variance, fat intake, and diabetes.

Enhörning S, Leosdottir M, Wallström P, Gullberg B, Berglund G, Wirfält E, Melander O.

Am J Clin Nutr. 2009 Jan;89(1):400-6. doi: 10.3945/ajcn.2008.26382. Epub 2008 Dec 3.

PMID:
19056558
12.

Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.

Furuhashi M, Tuncman G, Görgün CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS.

Nature. 2007 Jun 21;447(7147):959-65. Epub 2007 Jun 6.

13.

Anti-obesity effects of germinated brown rice extract through down-regulation of lipogenic genes in high fat diet-induced obese mice.

Ho JN, Son ME, Lim WC, Lim ST, Cho HY.

Biosci Biotechnol Biochem. 2012;76(6):1068-74. Epub 2012 Jun 7.

14.

Regulation of metabolic responses by adipocyte/macrophage Fatty Acid-binding proteins in leptin-deficient mice.

Cao H, Maeda K, Gorgun CZ, Kim HJ, Park SY, Shulman GI, Kim JK, Hotamisligil GS.

Diabetes. 2006 Jul;55(7):1915-22.

15.

Suppression of the C/EBP family of transcription factors in adipose tissue causes lipodystrophy.

Chatterjee R, Bhattacharya P, Gavrilova O, Glass K, Moitra J, Myakishev M, Pack S, Jou W, Feigenbaum L, Eckhaus M, Vinson C.

J Mol Endocrinol. 2011 Apr 15;46(3):175-92. doi: 10.1530/JME-10-0172. Print 2011 Jun.

16.

Combined adipocyte-macrophage fatty acid-binding protein deficiency improves metabolism, atherosclerosis, and survival in apolipoprotein E-deficient mice.

Boord JB, Maeda K, Makowski L, Babaev VR, Fazio S, Linton MF, Hotamisligil GS.

Circulation. 2004 Sep 14;110(11):1492-8. Epub 2004 Sep 7.

17.

Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.

Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.

J Biol Chem. 2006 Sep 8;281(36):26602-14. Epub 2006 Jun 29.

18.

Association between functional FABP2 promoter haplotype and type 2 diabetes.

Li Y, Fisher E, Klapper M, Boeing H, Pfeiffer A, Hampe J, Schreiber S, Burwinkel B, Schrezenmeir J, Döring F.

Horm Metab Res. 2006 May;38(5):300-7.

PMID:
16718625
19.

CCAAT/enhancer binding protein alpha (C/EBPalpha) in adipose tissue regulates genes in lipid and glucose metabolism and a genetic variation in C/EBPalpha is associated with serum levels of triglycerides.

Olofsson LE, Orho-Melander M, William-Olsson L, Sjöholm K, Sjöström L, Groop L, Carlsson B, Carlsson LM, Olsson B.

J Clin Endocrinol Metab. 2008 Dec;93(12):4880-6. doi: 10.1210/jc.2008-0574. Epub 2008 Sep 2.

PMID:
18765514

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