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Items: 1 to 20 of 117

1.

Mitochondrial involvement in amyotrophic lateral sclerosis: trigger or target?

Bacman SR, Bradley WG, Moraes CT.

Mol Neurobiol. 2006 Apr;33(2):113-31. Review.

PMID:
16603792
2.

Mitochondria in amyotrophic lateral sclerosis: a trigger and a target.

Dupuis L, Gonzalez de Aguilar JL, Oudart H, de Tapia M, Barbeito L, Loeffler JP.

Neurodegener Dis. 2004;1(6):245-54. Review.

PMID:
16908975
3.

Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G⁹³A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice.

Pehar M, Beeson G, Beeson CC, Johnson JA, Vargas MR.

PLoS One. 2014 Jul 23;9(7):e103438. doi: 10.1371/journal.pone.0103438. eCollection 2014.

4.

Molecular biology of amyotrophic lateral sclerosis: insights from genetics.

Pasinelli P, Brown RH.

Nat Rev Neurosci. 2006 Sep;7(9):710-23. Review.

PMID:
16924260
5.

The human G93A-superoxide dismutase-1 mutation, mitochondrial glutathione and apoptotic cell death.

Muyderman H, Hutson PG, Matusica D, Rogers ML, Rush RA.

Neurochem Res. 2009 Oct;34(10):1847-56. doi: 10.1007/s11064-009-9974-z. Epub 2009 Apr 28. Review.

PMID:
19399611
6.

Mitochondrial dysfunction and intracellular calcium dysregulation in ALS.

Kawamata H, Manfredi G.

Mech Ageing Dev. 2010 Jul-Aug;131(7-8):517-26. doi: 10.1016/j.mad.2010.05.003. Epub 2010 May 20. Review.

7.

Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis.

Parone PA, Da Cruz S, Han JS, McAlonis-Downes M, Vetto AP, Lee SK, Tseng E, Cleveland DW.

J Neurosci. 2013 Mar 13;33(11):4657-71. doi: 10.1523/JNEUROSCI.1119-12.2013.

8.

Fas(t) balls and Lou Gehrig disease. A clue to selective vulnerability of motor neurons?

Xiong ZQ, McNamara JO.

Neuron. 2002 Sep 12;35(6):1011-3. Review.

10.

Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis.

Menzies FM, Cookson MR, Taylor RW, Turnbull DM, Chrzanowska-Lightowlers ZM, Dong L, Figlewicz DA, Shaw PJ.

Brain. 2002 Jul;125(Pt 7):1522-33.

PMID:
12077002
11.

Mitochondrial dysfunction and its role in motor neuron degeneration in ALS.

Manfredi G, Xu Z.

Mitochondrion. 2005 Apr;5(2):77-87. Review.

PMID:
16050975
12.

Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo.

Chi L, Ke Y, Luo C, Gozal D, Liu R.

Neuroscience. 2007 Feb 9;144(3):991-1003. Epub 2006 Dec 5.

13.

Cdk5 sinks into ALS.

Patzke H, Tsai LH.

Trends Neurosci. 2002 Jan;25(1):8-10. Review.

PMID:
11801324
14.

Determinants of rapid disease progression in ALS.

Yamanaka K, Cleveland DW.

Neurology. 2005 Dec 27;65(12):1859-60. No abstract available.

PMID:
16380607
15.

Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels.

Zimmerman MC, Oberley LW, Flanagan SW.

J Neurochem. 2007 Aug;102(3):609-18. Epub 2007 Mar 23.

16.

The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice.

Martin LJ, Gertz B, Pan Y, Price AC, Molkentin JD, Chang Q.

Exp Neurol. 2009 Aug;218(2):333-46. doi: 10.1016/j.expneurol.2009.02.015. Epub 2009 Mar 9.

17.

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.

Watanabe M, Dykes-Hoberg M, Culotta VC, Price DL, Wong PC, Rothstein JD.

Neurobiol Dis. 2001 Dec;8(6):933-41.

PMID:
11741389
18.

Rodent Models of Amyotrophic Lateral Sclerosis.

Philips T, Rothstein JD.

Curr Protoc Pharmacol. 2015 Jun 1;69:5.67.1-21. doi: 10.1002/0471141755.ph0567s69. Review.

19.

Mitochondrial dysfunction in amyotrophic lateral sclerosis.

Shi P, Gal J, Kwinter DM, Liu X, Zhu H.

Biochim Biophys Acta. 2010 Jan;1802(1):45-51. doi: 10.1016/j.bbadis.2009.08.012. Epub 2009 Aug 26. Review.

20.

Rapid disease progression correlates with instability of mutant SOD1 in familial ALS.

Sato T, Nakanishi T, Yamamoto Y, Andersen PM, Ogawa Y, Fukada K, Zhou Z, Aoike F, Sugai F, Nagano S, Hirata S, Ogawa M, Nakano R, Ohi T, Kato T, Nakagawa M, Hamasaki T, Shimizu A, Sakoda S.

Neurology. 2005 Dec 27;65(12):1954-7. Epub 2005 Nov 16.

PMID:
16291929

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