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Tumor targeting by an aptamer.

Hicke BJ, Stephens AW, Gould T, Chang YF, Lynott CK, Heil J, Borkowski S, Hilger CS, Cook G, Warren S, Schmidt PG.

J Nucl Med. 2006 Apr;47(4):668-78.


Conjugation with (111)In-DTPA-poly(ethylene glycol) improves imaging of anti-EGF receptor antibody C225.

Wen X, Wu QP, Ke S, Ellis L, Charnsangavej C, Delpassand AS, Wallace S, Li C.

J Nucl Med. 2001 Oct;42(10):1530-7.


Tumor targeting with a (99m)Tc-labeled AS1411 aptamer in prostate tumor cells.

Noaparast Z, Hosseinimehr SJ, Piramoon M, Abedi SM.

J Drug Target. 2015;23(6):497-505. doi: 10.3109/1061186X.2015.1009075. Epub 2015 Feb 12.


Using radiolabeled DNA as an imaging agent to recognize protein targets.

Gambhir SS.

J Nucl Med. 2006 Apr;47(4):557-8. No abstract available.


PET imaging of tenascin-C with a radiolabeled single-stranded DNA aptamer.

Jacobson O, Yan X, Niu G, Weiss ID, Ma Y, Szajek LP, Shen B, Kiesewetter DO, Chen X.

J Nucl Med. 2015 Apr;56(4):616-21. doi: 10.2967/jnumed.114.149484. Epub 2015 Feb 19.


In vivo biodistribution, PET imaging, and tumor accumulation of 86Y- and 111In-antimindin/RG-1, engineered antibody fragments in LNCaP tumor-bearing nude mice.

Schneider DW, Heitner T, Alicke B, Light DR, McLean K, Satozawa N, Parry G, Yoo J, Lewis JS, Parry R.

J Nucl Med. 2009 Mar;50(3):435-43. doi: 10.2967/jnumed.108.055608. Epub 2009 Feb 17.


2-Mercaptoacetylglycylglycyl (MAG2) as a bifunctional chelator for 99mTc-labeling of cyclic RGD dimers: effect of technetium chelate on tumor uptake and pharmacokinetics.

Shi J, Kim YS, Chakraborty S, Jia B, Wang F, Liu S.

Bioconjug Chem. 2009 Aug 19;20(8):1559-68. doi: 10.1021/bc9001739. Epub 2009 Jul 15.


Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors.

Xiang D, Zheng C, Zhou SF, Qiao S, Tran PH, Pu C, Li Y, Kong L, Kouzani AZ, Lin J, Liu K, Li L, Shigdar S, Duan W.

Theranostics. 2015 Jul 2;5(10):1083-97. doi: 10.7150/thno.11711. eCollection 2015.


99mTc-Mercaptoacetyl-Glu-Glu-aptamer specific for tenascin-C .

Zhang H.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2008 Jul 17 [updated 2008 Aug 12].


Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor alphavbeta3-integrin expression.

Chen X, Hou Y, Tohme M, Park R, Khankaldyyan V, Gonzales-Gomez I, Bading JR, Laug WE, Conti PS.

J Nucl Med. 2004 Oct;45(10):1776-83.


Anti-MUC1 aptamers: radiolabelling with (99m)Tc and biodistribution in MCF-7 tumour-bearing mice.

Pieve CD, Perkins AC, Missailidis S.

Nucl Med Biol. 2009 Aug;36(6):703-10. doi: 10.1016/j.nucmedbio.2009.04.004.


In vivo imaging of human colon cancer xenografts in immunodeficient mice using a guanylyl cyclase C--specific ligand.

Wolfe HR, Mendizabal M, Lleong E, Cuthbertson A, Desai V, Pullan S, Fujii DK, Morrison M, Pither R, Waldman SA.

J Nucl Med. 2002 Mar;43(3):392-9.


In vitro and in vivo evaluation of (99m)Tc-DO3A-EA-Folate for receptor-mediated targeting of folate positive tumors.

Mishra G, Hazari PP, Kumar N, Mishra AK.

J Drug Target. 2011 Nov;19(9):761-9. doi: 10.3109/1061186X.2011.561857. Epub 2011 Mar 22.


A folate receptor-α-specific ligand that targets cancer tissue and not sites of inflammation.

Vaitilingam B, Chelvam V, Kularatne SA, Poh S, Ayala-Lopez W, Low PS.

J Nucl Med. 2012 Jul;53(7):1127-34. doi: 10.2967/jnumed.111.099390. Epub 2012 Jun 12.


In vivo detection of small tumour lesions by multi-pinhole SPECT applying a (99m)Tc-labelled nanobody targeting the Epidermal Growth Factor Receptor.

Krüwel T, Nevoltris D, Bode J, Dullin C, Baty D, Chames P, Alves F.

Sci Rep. 2016 Feb 25;6:21834. doi: 10.1038/srep21834.


99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer.

Hillier SM, Maresca KP, Lu G, Merkin RD, Marquis JC, Zimmerman CN, Eckelman WC, Joyal JL, Babich JW.

J Nucl Med. 2013 Aug;54(8):1369-76. doi: 10.2967/jnumed.112.116624. Epub 2013 Jun 3.


PEGylation of (99m)Tc-labeled bombesin analogues improves their pharmacokinetic properties.

Däpp S, García Garayoa E, Maes V, Brans L, Tourwé DA, Müller C, Schibli R.

Nucl Med Biol. 2011 Oct;38(7):997-1009. doi: 10.1016/j.nucmedbio.2011.02.014. Epub 2011 Apr 21.


99mTcO(MAG2-3G3-dimer): a new integrin alpha(v)beta(3)-targeted SPECT radiotracer with high tumor uptake and favorable pharmacokinetics.

Shi J, Wang L, Kim YS, Zhai S, Jia B, Wang F, Liu S.

Eur J Nucl Med Mol Imaging. 2009 Nov;36(11):1874-84. doi: 10.1007/s00259-009-1166-1. Epub 2009 May 30.


Specific localization, gamma camera imaging, and intracellular trafficking of radiolabelled chimeric anti-G(D3) ganglioside monoclonal antibody KM871 in SK-MEL-28 melanoma xenografts.

Lee FT, Rigopoulos A, Hall C, Clarke K, Cody SH, Smyth FE, Liu Z, Brechbiel MW, Hanai N, Nice EC, Catimel B, Burgess AW, Welt S, Ritter G, Old LJ, Scott AM.

Cancer Res. 2001 Jun 1;61(11):4474-82.

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