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Items: 1 to 20 of 95


Hsp70 inhibits aminoglycoside-induced hair cell death and is necessary for the protective effect of heat shock.

Taleb M, Brandon CS, Lee FS, Lomax MI, Dillmann WH, Cunningham LL.

J Assoc Res Otolaryngol. 2008 Sep;9(3):277-89. doi: 10.1007/s10162-008-0122-2. Epub 2008 May 30.


Heat shock inhibits both aminoglycoside- and cisplatin-induced sensory hair cell death.

Cunningham LL, Brandon CS.

J Assoc Res Otolaryngol. 2006 Sep;7(3):299-307. Epub 2006 Jun 23.


Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32.

Francis SP, Kramarenko II, Brandon CS, Lee FS, Baker TG, Cunningham LL.

Cell Death Dis. 2011 Aug 25;2:e195. doi: 10.1038/cddis.2011.76.


Hsp70 inhibits aminoglycoside-induced hearing loss and cochlear hair cell death.

Taleb M, Brandon CS, Lee FS, Harris KC, Dillmann WH, Cunningham LL.

Cell Stress Chaperones. 2009 Jul;14(4):427-37. doi: 10.1007/s12192-008-0097-2. Epub 2009 Jan 15.


Live imaging the phagocytic activity of inner ear supporting cells in response to hair cell death.

Monzack EL, May LA, Roy S, Gale JE, Cunningham LL.

Cell Death Differ. 2015 Dec;22(12):1995-2005. doi: 10.1038/cdd.2015.48. Epub 2015 May 1.


Using the zebrafish lateral line to screen for ototoxicity.

Chiu LL, Cunningham LL, Raible DW, Rubel EW, Ou HC.

J Assoc Res Otolaryngol. 2008 Jun;9(2):178-90. doi: 10.1007/s10162-008-0118-y. Epub 2008 Apr 12.


Sound preconditioning therapy inhibits ototoxic hearing loss in mice.

Roy S, Ryals MM, Van den Bruele AB, Fitzgerald TS, Cunningham LL.

J Clin Invest. 2013 Nov;123(11):4945-9. Erratum in: J Clin Invest. 2014 Jan 2;124(1):461.


Caspase activation in hair cells of the mouse utricle exposed to neomycin.

Cunningham LL, Cheng AG, Rubel EW.

J Neurosci. 2002 Oct 1;22(19):8532-40.


Coenzyme Q10 protects hair cells against aminoglycoside.

Sugahara K, Hirose Y, Mikuriya T, Hashimoto M, Kanagawa E, Hara H, Shimogori H, Yamashita H.

PLoS One. 2014 Sep 29;9(9):e108280. doi: 10.1371/journal.pone.0108280. eCollection 2014.


Characterization of leukocyte subtypes in chicken inner ear sensory epithelia.

O'Halloran EK, Oesterle EC.

J Comp Neurol. 2004 Jul 26;475(3):340-60.


Cisplatin exposure damages resident stem cells of the mammalian inner ear.

Slattery EL, Oshima K, Heller S, Warchol ME.

Dev Dyn. 2014 Oct;243(10):1328-37. doi: 10.1002/dvdy.24150. Epub 2014 Jun 25.


Spontaneous hair cell regeneration in the mouse utricle following gentamicin ototoxicity.

Kawamoto K, Izumikawa M, Beyer LA, Atkin GM, Raphael Y.

Hear Res. 2009 Jan;247(1):17-26. doi: 10.1016/j.heares.2008.08.010. Epub 2008 Sep 7.


Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death.

Owens KN, Santos F, Roberts B, Linbo T, Coffin AB, Knisely AJ, Simon JA, Rubel EW, Raible DW.

PLoS Genet. 2008 Feb 29;4(2):e1000020. doi: 10.1371/journal.pgen.1000020.


Dissection of adult mouse utricle and adenovirus-mediated supporting-cell infection.

Brandon CS, Voelkel-Johnson C, May LA, Cunningham LL.

J Vis Exp. 2012 Mar 28;(61). pii: 3734. doi: 10.3791/3734.


Identification of FDA-approved drugs and bioactives that protect hair cells in the zebrafish (Danio rerio) lateral line and mouse (Mus musculus) utricle.

Ou HC, Cunningham LL, Francis SP, Brandon CS, Simon JA, Raible DW, Rubel EW.

J Assoc Res Otolaryngol. 2009 Jun;10(2):191-203. doi: 10.1007/s10162-009-0158-y. Epub 2009 Feb 25.


Survival of bundleless hair cells and subsequent bundle replacement in the bullfrog's saccule.

Gale JE, Meyers JR, Periasamy A, Corwin JT.

J Neurobiol. 2002 Feb 5;50(2):81-92.


Caspase inhibitors promote vestibular hair cell survival and function after aminoglycoside treatment in vivo.

Matsui JI, Haque A, Huss D, Messana EP, Alosi JA, Roberson DW, Cotanche DA, Dickman JD, Warchol ME.

J Neurosci. 2003 Jul 9;23(14):6111-22.


Cisplatin-induced hair cell death requires STAT1 and is attenuated by epigallocatechin gallate.

Schmitt NC, Rubel EW, Nathanson NM.

J Neurosci. 2009 Mar 25;29(12):3843-51. doi: 10.1523/JNEUROSCI.5842-08.2009.

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