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Items: 1 to 20 of 112


Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear.

Qian D, Radde-Gallwitz K, Kelly M, Tyrberg B, Kim J, Gao WQ, Chen P.

Dev Dyn. 2006 Jun;235(6):1689-700.


Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear.

Zine A, Aubert A, Qiu J, Therianos S, Guillemot F, Kageyama R, de Ribaupierre F.

J Neurosci. 2001 Jul 1;21(13):4712-20.


Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells.

Scheffer D, Sage C, Corey DP, Pingault V.

FEBS Lett. 2007 Oct 2;581(24):4651-6. Epub 2007 Sep 4.


Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development.

Raft S, Koundakjian EJ, Quinones H, Jayasena CS, Goodrich LV, Johnson JE, Segil N, Groves AK.

Development. 2007 Dec;134(24):4405-15.


Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia.

Kirjavainen A, Sulg M, Heyd F, Alitalo K, Ylä-Herttuala S, Möröy T, Petrova TV, Pirvola U.

Dev Biol. 2008 Oct 1;322(1):33-45. doi: 10.1016/j.ydbio.2008.07.004. Epub 2008 Jul 9.


Atoh1: landscape for inner ear cell regeneration.

Hongmiao R, Wei L, Bing H, Xiong DD, Jihao R.

Curr Gene Ther. 2014;14(2):101-11. Review.


Atoh1 directs hair cell differentiation and survival in the late embryonic mouse inner ear.

Chonko KT, Jahan I, Stone J, Wright MC, Fujiyama T, Hoshino M, Fritzsch B, Maricich SM.

Dev Biol. 2013 Sep 15;381(2):401-10. doi: 10.1016/j.ydbio.2013.06.022. Epub 2013 Jun 21.


A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability.

Pan N, Jahan I, Kersigo J, Duncan JS, Kopecky B, Fritzsch B.

PLoS One. 2012;7(1):e30358. doi: 10.1371/journal.pone.0030358. Epub 2012 Jan 18.


The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival.

Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ.

Development. 2003 Jan;130(1):221-32.


Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea.

Jahan I, Pan N, Kersigo J, Fritzsch B.

PLoS One. 2010 Jul 22;5(7):e11661. doi: 10.1371/journal.pone.0011661.


Rbpj regulates development of prosensory cells in the mammalian inner ear.

Yamamoto N, Chang W, Kelley MW.

Dev Biol. 2011 May 15;353(2):367-79. doi: 10.1016/j.ydbio.2011.03.016. Epub 2011 Mar 21.


Hes1 is a negative regulator of inner ear hair cell differentiation.

Zheng JL, Shou J, Guillemot F, Kageyama R, Gao WQ.

Development. 2000 Nov;127(21):4551-60.


Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit.

Matei V, Pauley S, Kaing S, Rowitch D, Beisel KW, Morris K, Feng F, Jones K, Lee J, Fritzsch B.

Dev Dyn. 2005 Nov;234(3):633-50.


Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear.

Radde-Gallwitz K, Pan L, Gan L, Lin X, Segil N, Chen P.

J Comp Neurol. 2004 Sep 27;477(4):412-21.


Math1: an essential gene for the generation of inner ear hair cells.

Bermingham NA, Hassan BA, Price SD, Vollrath MA, Ben-Arie N, Eatock RA, Bellen HJ, Lysakowski A, Zoghbi HY.

Science. 1999 Jun 11;284(5421):1837-41.


Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea.

Hartman BH, Basak O, Nelson BR, Taylor V, Bermingham-McDonogh O, Reh TA.

J Assoc Res Otolaryngol. 2009 Sep;10(3):321-40. doi: 10.1007/s10162-009-0162-2. Epub 2009 Apr 17.


Math1 regulates development of the sensory epithelium in the mammalian cochlea.

Woods C, Montcouquiol M, Kelley MW.

Nat Neurosci. 2004 Dec;7(12):1310-8. Epub 2004 Nov 7.


Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.

Pan N, Jahan I, Kersigo J, Kopecky B, Santi P, Johnson S, Schmitz H, Fritzsch B.

Hear Res. 2011 May;275(1-2):66-80. doi: 10.1016/j.heares.2010.12.002. Epub 2010 Dec 10.

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