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Items: 1 to 20 of 57

1.

A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding.

Totzke G, Essmann F, Pohlmann S, Lindenblatt C, Jänicke RU, Schulze-Osthoff K.

J Biol Chem. 2006 May 5;281(18):12645-54. Epub 2006 Mar 2.

2.

A novel IkappaB protein, IkappaB-zeta, induced by proinflammatory stimuli, negatively regulates nuclear factor-kappaB in the nuclei.

Yamazaki S, Muta T, Takeshige K.

J Biol Chem. 2001 Jul 20;276(29):27657-62. Epub 2001 May 16.

3.

Positive and negative regulation of nuclear factor-kappaB-mediated transcription by IkappaB-zeta, an inducible nuclear protein.

Motoyama M, Yamazaki S, Eto-Kimura A, Takeshige K, Muta T.

J Biol Chem. 2005 Mar 4;280(9):7444-51. Epub 2004 Dec 23.

4.
5.

The nuclear I kappaB protein I kappaB zeta specifically binds NF-kappaB p50 homodimers and forms a ternary complex on kappaB DNA.

Trinh DV, Zhu N, Farhang G, Kim BJ, Huxford T.

J Mol Biol. 2008 May 23;379(1):122-35. doi: 10.1016/j.jmb.2008.03.060. Epub 2008 Apr 3.

PMID:
18436238
6.

IkappaB-zeta, a new anti-inflammatory nuclear protein induced by lipopolysaccharide, is a negative regulator for nuclear factor-kappaB.

Muta T, Yamazaki S, Eto A, Motoyama M, Takeshige K.

J Endotoxin Res. 2003;9(3):187-91.

PMID:
12831461
7.

Tumor suppressor SMAR1 represses IkappaBalpha expression and inhibits p65 transactivation through matrix attachment regions.

Singh K, Sinha S, Malonia SK, Bist P, Tergaonkar V, Chattopadhyay S.

J Biol Chem. 2009 Jan 9;284(2):1267-78. doi: 10.1074/jbc.M801088200. Epub 2008 Nov 3.

8.
9.

Protein kinase Cdelta activates RelA/p65 and nuclear factor-kappaB signaling in response to tumor necrosis factor-alpha.

Lu ZG, Liu H, Yamaguchi T, Miki Y, Yoshida K.

Cancer Res. 2009 Jul 15;69(14):5927-35. doi: 10.1158/0008-5472.CAN-08-4786. Epub 2009 Jun 23.

10.

N-tosyl-L-phenylalanine chloromethyl ketone inhibits NF-kappaB activation by blocking specific cysteine residues of IkappaB kinase beta and p65/RelA.

Ha KH, Byun MS, Choi J, Jeong J, Lee KJ, Jue DM.

Biochemistry. 2009 Aug 4;48(30):7271-8. doi: 10.1021/bi900660f.

PMID:
19591457
11.

Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.

Tse AK, Wan CK, Zhu GY, Shen XL, Cheung HY, Yang M, Fong WF.

Mol Immunol. 2007 Apr;44(10):2647-58. Epub 2007 Jan 22.

PMID:
17240450
12.
13.

PMX464, a thiol-reactive quinol and putative thioredoxin inhibitor, inhibits NF-kappaB-dependent proinflammatory activation of alveolar epithelial cells.

Callister ME, Pinhu L, Catley MC, Westwell AD, Newton R, Leaver SK, Quinlan GJ, Evans TW, Griffiths MJ, Burke-Gaffney A.

Br J Pharmacol. 2008 Nov;155(5):661-72. doi: 10.1038/bjp.2008.258. Epub 2008 Jun 30.

14.

Nuclear protein IkappaB-zeta inhibits the activity of STAT3.

Wu Z, Zhang X, Yang J, Wu G, Zhang Y, Yuan Y, Jin C, Chang Z, Wang J, Yang X, He F.

Biochem Biophys Res Commun. 2009 Sep 18;387(2):348-52. doi: 10.1016/j.bbrc.2009.07.023. Epub 2009 Jul 10.

PMID:
19595668
15.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M.

Sci STKE. 2006 Oct 17;2006(357):re13. Review.

PMID:
17047224
16.

Copine-I represses NF-kappaB transcription by endoproteolysis of p65.

Ramsey CS, Yeung F, Stoddard PB, Li D, Creutz CE, Mayo MW.

Oncogene. 2008 Jun 5;27(25):3516-26. doi: 10.1038/sj.onc.1211030. Epub 2008 Jan 21.

PMID:
18212740
17.

PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion.

Kinoshita T, Wang Y, Hasegawa M, Imamura R, Suda T.

J Biol Chem. 2005 Jun 10;280(23):21720-5. Epub 2005 Apr 6.

18.

17-Acetoxyjolkinolide B irreversibly inhibits IkappaB kinase and induces apoptosis of tumor cells.

Yan SS, Li Y, Wang Y, Shen SS, Gu Y, Wang HB, Qin GW, Yu Q.

Mol Cancer Ther. 2008 Jun;7(6):1523-32. doi: 10.1158/1535-7163.MCT-08-0263.

19.

Wnt/beta-catenin signaling regulates cytokine-induced human inducible nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells.

Du Q, Zhang X, Cardinal J, Cao Z, Guo Z, Shao L, Geller DA.

Cancer Res. 2009 May 1;69(9):3764-71. doi: 10.1158/0008-5472.CAN-09-0014. Epub 2009 Apr 21.

20.

Methylglyoxal suppresses TNF-alpha-induced NF-kappaB activation by inhibiting NF-kappaB DNA-binding.

Laga M, Cottyn A, Van Herreweghe F, Vanden Berghe W, Haegeman G, Van Oostveldt P, Vandekerckhove J, Vancompernolle K.

Biochem Pharmacol. 2007 Aug 15;74(4):579-89. Epub 2007 Jun 3.

PMID:
17617381

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