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Items: 1 to 20 of 97


Crystal structure and nonhomologous end-joining function of the ligase component of Mycobacterium DNA ligase D.

Akey D, Martins A, Aniukwu J, Glickman MS, Shuman S, Berger JM.

J Biol Chem. 2006 May 12;281(19):13412-23. Epub 2006 Feb 13.


Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D.

Zhu H, Nandakumar J, Aniukwu J, Wang LK, Glickman MS, Lima CD, Shuman S.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1711-6. Epub 2006 Jan 30.


DNA ligase C1 mediates the LigD-independent nonhomologous end-joining pathway of Mycobacterium smegmatis.

Bhattarai H, Gupta R, Glickman MS.

J Bacteriol. 2014 Oct;196(19):3366-76. doi: 10.1128/JB.01832-14. Epub 2014 Jun 23.


The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends.

Aniukwu J, Glickman MS, Shuman S.

Genes Dev. 2008 Feb 15;22(4):512-27. doi: 10.1101/gad.1631908.


Structure of a NHEJ polymerase-mediated DNA synaptic complex.

Brissett NC, Pitcher RS, Juarez R, Picher AJ, Green AJ, Dafforn TR, Fox GC, Blanco L, Doherty AJ.

Science. 2007 Oct 19;318(5849):456-9.


Characterization of the roles of the catalytic domains of Mycobacterium tuberculosis ligase D in Ku-dependent error-prone DNA end joining.

Wright D, DeBeaux A, Shi R, Doherty AJ, Harrison L.

Mutagenesis. 2010 Sep;25(5):473-81. doi: 10.1093/mutage/geq029. Epub 2010 Jun 7.


Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C.

Gong C, Bongiorno P, Martins A, Stephanou NC, Zhu H, Shuman S, Glickman MS.

Nat Struct Mol Biol. 2005 Apr;12(4):304-12. Epub 2005 Mar 20.


Characterization of Agrobacterium tumefaciens DNA ligases C and D.

Zhu H, Shuman S.

Nucleic Acids Res. 2007;35(11):3631-45. Epub 2007 May 8.


Bacterial nonhomologous end joining ligases preferentially seal breaks with a 3'-OH monoribonucleotide.

Zhu H, Shuman S.

J Biol Chem. 2008 Mar 28;283(13):8331-9. doi: 10.1074/jbc.M705476200. Epub 2008 Jan 17.


A primer-dependent polymerase function of pseudomonas aeruginosa ATP-dependent DNA ligase (LigD).

Zhu H, Shuman S.

J Biol Chem. 2005 Jan 7;280(1):418-27. Epub 2004 Oct 31.


Characterization of Mycobacterium smegmatis PolD2 and PolD1 as RNA/DNA polymerases homologous to the POL domain of bacterial DNA ligase D.

Zhu H, Bhattarai H, Yan HG, Shuman S, Glickman MS.

Biochemistry. 2012 Dec 21;51(51):10147-58. doi: 10.1021/bi301202e. Epub 2012 Dec 11.


Essential constituents of the 3'-phosphoesterase domain of bacterial DNA ligase D, a nonhomologous end-joining enzyme.

Zhu H, Wang LK, Shuman S.

J Biol Chem. 2005 Oct 7;280(40):33707-15. Epub 2005 Jul 25.


Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily.

Nair PA, Smith P, Shuman S.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12822-7. doi: 10.1073/pnas.1005830107. Epub 2010 Jun 29.


Biochemical and genetic analysis of the four DNA ligases of mycobacteria.

Gong C, Martins A, Bongiorno P, Glickman M, Shuman S.

J Biol Chem. 2004 May 14;279(20):20594-606. Epub 2004 Feb 25.


Structure and function of a mycobacterial NHEJ DNA repair polymerase.

Pitcher RS, Brissett NC, Picher AJ, Andrade P, Juarez R, Thompson D, Fox GC, Blanco L, Doherty AJ.

J Mol Biol. 2007 Feb 16;366(2):391-405. Epub 2006 Oct 20.


Sequence-specific 1H, 13C and 15N assignments of the phosphoesterase (PE) domain of Pseudomonas aeruginosa DNA ligase D (LigD).

Dutta K, Natarajan A, Nair PA, Shuman S, Ghose R.

Biomol NMR Assign. 2011 Oct;5(2):151-5. doi: 10.1007/s12104-010-9289-7. Epub 2011 Jan 7.


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