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Items: 1 to 20 of 336

1.

Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.

Tahara H, Kusuhara H, Maeda K, Koepsell H, Fuse E, Sugiyama Y.

Drug Metab Dispos. 2006 May;34(5):743-7. Epub 2006 Feb 2.

2.

The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.

Matsushima S, Maeda K, Inoue K, Ohta KY, Yuasa H, Kondo T, Nakayama H, Horita S, Kusuhara H, Sugiyama Y.

Drug Metab Dispos. 2009 Mar;37(3):555-9. doi: 10.1124/dmd.108.023911. Epub 2008 Dec 12.

3.

Human organic anion transporters and human organic cation transporters mediate renal antiviral transport.

Takeda M, Khamdang S, Narikawa S, Kimura H, Kobayashi Y, Yamamoto T, Cha SH, Sekine T, Endou H.

J Pharmacol Exp Ther. 2002 Mar;300(3):918-24.

4.

Preclinical and clinical evidence for the collaborative transport and renal secretion of an oxazolidinone antibiotic by organic anion transporter 3 (OAT3/SLC22A8) and multidrug and toxin extrusion protein 1 (MATE1/SLC47A1).

Lai Y, Sampson KE, Balogh LM, Brayman TG, Cox SR, Adams WJ, Kumar V, Stevens JC.

J Pharmacol Exp Ther. 2010 Sep 1;334(3):936-44. doi: 10.1124/jpet.110.170753. Epub 2010 Jun 2.

5.

Organic anion transporters involved in the excretion of bestatin in the kidney.

Zhu Y, Meng Q, Wang C, Liu Q, Sun H, Kaku T, Liu K.

Peptides. 2012 Feb;33(2):265-71. doi: 10.1016/j.peptides.2012.01.007. Epub 2012 Jan 18.

PMID:
22273603
6.

A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters.

Tahara H, Kusuhara H, Endou H, Koepsell H, Imaoka T, Fuse E, Sugiyama Y.

J Pharmacol Exp Ther. 2005 Oct;315(1):337-45. Epub 2005 Jul 8.

7.

Characterization of methotrexate transport and its drug interactions with human organic anion transporters.

Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H.

J Pharmacol Exp Ther. 2002 Aug;302(2):666-71.

8.

Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins.

Kimura H, Takeda M, Narikawa S, Enomoto A, Ichida K, Endou H.

J Pharmacol Exp Ther. 2002 Apr;301(1):293-8.

9.

Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine.

Liu S, Beringer PM, Hidayat L, Rao AP, Louie S, Burckart GJ, Shapiro B.

J Clin Pharmacol. 2008 Aug;48(8):957-65. doi: 10.1177/0091270008319707. Epub 2008 May 29.

PMID:
18511651
10.

Interaction and transport characteristics of mycophenolic acid and its glucuronide via human organic anion transporters hOAT1 and hOAT3.

Uwai Y, Motohashi H, Tsuji Y, Ueo H, Katsura T, Inui K.

Biochem Pharmacol. 2007 Jun 30;74(1):161-8. Epub 2007 Mar 30.

PMID:
17462604
11.

Renal transport of adefovir, cidofovir, and tenofovir by SLC22A family members (hOAT1, hOAT3, and hOCT2).

Uwai Y, Ida H, Tsuji Y, Katsura T, Inui K.

Pharm Res. 2007 Apr;24(4):811-5. Epub 2007 Feb 15.

PMID:
17372702
12.

Human organic anion transporters 1 (hOAT1/SLC22A6) and 3 (hOAT3/SLC22A8) transport edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one) and its sulfate conjugate.

Mizuno N, Takahashi T, Iwase Y, Kusuhara H, Niwa T, Sugiyama Y.

Drug Metab Dispos. 2007 Aug;35(8):1429-34. Epub 2007 May 14.

13.

Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human kidney drug transporters.

Han YH, Busler D, Hong Y, Tian Y, Chen C, Rodrigues AD.

Drug Metab Dispos. 2010 Jul;38(7):1064-71. doi: 10.1124/dmd.109.031526. Epub 2010 Apr 1.

15.

Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors.

Enomoto A, Takeda M, Shimoda M, Narikawa S, Kobayashi Y, Kobayashi Y, Yamamoto T, Sekine T, Cha SH, Niwa T, Endou H.

J Pharmacol Exp Ther. 2002 Jun;301(3):797-802.

16.

Aspirin and probenecid inhibit organic anion transporter 3-mediated renal uptake of cilostazol and probenecid induces metabolism of cilostazol in the rat.

Wang C, Wang C, Liu Q, Meng Q, Cang J, Sun H, Peng J, Ma X, Huo X, Liu K.

Drug Metab Dispos. 2014 Jun;42(6):996-1007. doi: 10.1124/dmd.113.055194. Epub 2014 Apr 1.

17.

Renal organic anion transporter-mediated drug-drug interaction between gemcabene and quinapril.

Yuan H, Feng B, Yu Y, Chupka J, Zheng JY, Heath TG, Bond BR.

J Pharmacol Exp Ther. 2009 Jul;330(1):191-7. doi: 10.1124/jpet.108.149476. Epub 2009 Apr 6.

18.

Transport of the natural sweetener stevioside and its aglycone steviol by human organic anion transporter (hOAT1; SLC22A6) and hOAT3 (SLC22A8).

Srimaroeng C, Chatsudthipong V, Aslamkhan AG, Pritchard JB.

J Pharmacol Exp Ther. 2005 May;313(2):621-8. Epub 2005 Jan 11.

19.

Renal organic anion transporters OAT1 and OAT3 mediate the cellular accumulation of 5-sulfooxymethylfurfural, a reactive, nephrotoxic metabolite of the Maillard product 5-hydroxymethylfurfural.

Bakhiya N, Monien B, Frank H, Seidel A, Glatt H.

Biochem Pharmacol. 2009 Aug 15;78(4):414-9. doi: 10.1016/j.bcp.2009.04.017. Epub 2009 Apr 24.

PMID:
19394312
20.

Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.

Yasui-Furukori N, Uno T, Sugawara K, Tateishi T.

Clin Pharmacol Ther. 2005 Jan;77(1):17-23.

PMID:
15637527

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