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Items: 1 to 20 of 130

1.
3.

Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.

Kohashi T, Maekawa S, Sakamoto N, Kurosaki M, Watanabe H, Tanabe Y, Chen CH, Kanazawa N, Nakagawa M, Kakinuma S, Yamashiro T, Itsui Y, Koyama T, Enomoto N, Watanabe M.

J Viral Hepat. 2006 Sep;13(9):582-90.

PMID:
16907844
4.

Is investigation of hepatitis C virus NS5A gene heterogeneity a tool for predicting long-lasting response to interferon therapy in patients with HCV-1b chronic hepatitis?

Squadrito G, Raffa G, Restuccia T, Pollicino T, Brancatelli S, Raimondo G.

J Viral Hepat. 2002 Sep;9(5):360-9.

PMID:
12225331
5.

Dominant negative effect of wild-type NS5A on NS5A-adapted subgenomic hepatitis C virus RNA replicon.

Graziani R, Paonessa G.

J Gen Virol. 2004 Jul;85(Pt 7):1867-75.

PMID:
15218171
6.

The non-structural 5A protein of hepatitis C virus exhibits genotypic differences in interferon antagonism.

Tsai YH, Kuang WF, Lu TY, Kao JH, Lai MY, Liu CJ, Chen PJ, Hwang LH.

J Hepatol. 2008 Dec;49(6):899-907. doi: 10.1016/j.jhep.2008.06.030. Epub 2008 Sep 16.

PMID:
18842320
7.

Trans-complementation of HCV replication by non-structural protein 5A.

Tong X, Malcolm BA.

Virus Res. 2006 Feb;115(2):122-30. Epub 2005 Sep 15.

PMID:
16146661
8.

[Interferon resistance and ISDR (interferon sensitivity determining region)].

Amemiya F, Maekawa S, Enomoto N.

Nihon Rinsho. 2006 Jul;64(7):1249-53. Review. Japanese.

PMID:
16838640
9.

Introduction of NS5A mutations enables subgenomic HCV replicon derived from chimpanzee-infectious HC-J4 isolate to replicate efficiently in Huh-7 cells.

Maekawa S, Enomoto N, Sakamoto N, Kurosaki M, Ueda E, Kohashi T, Watanabe H, Chen CH, Yamashiro T, Tanabe Y, Kanazawa N, Nakagawa M, Sato C, Watanabe M.

J Viral Hepat. 2004 Sep;11(5):394-403.

PMID:
15357644
10.

Characterization of the effects of hepatitis C virus nonstructural 5A protein expression in human cell lines and on interferon-sensitive virus replication.

Polyak SJ, Paschal DM, McArdle S, Gale MJ Jr, Moradpour D, Gretch DR.

Hepatology. 1999 Apr;29(4):1262-71.

PMID:
10094974
11.

The non-structural 5A protein of hepatitis C virus.

Pawlotsky JM, Germanidis G.

J Viral Hepat. 1999 Sep;6(5):343-56. Review.

PMID:
10607250
12.
13.

Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

Appel N, Zayas M, Miller S, Krijnse-Locker J, Schaller T, Friebe P, Kallis S, Engel U, Bartenschlager R.

PLoS Pathog. 2008 Mar 28;4(3):e1000035. doi: 10.1371/journal.ppat.1000035.

14.

The C terminus of hepatitis C virus NS4A encodes an electrostatic switch that regulates NS5A hyperphosphorylation and viral replication.

Lindenbach BD, Prágai BM, Montserret R, Beran RK, Pyle AM, Penin F, Rice CM.

J Virol. 2007 Sep;81(17):8905-18. Epub 2007 Jun 20.

15.

Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.

Hamamoto I, Nishimura Y, Okamoto T, Aizaki H, Liu M, Mori Y, Abe T, Suzuki T, Lai MM, Miyamura T, Moriishi K, Matsuura Y.

J Virol. 2005 Nov;79(21):13473-82.

16.

Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles.

Hughes M, Griffin S, Harris M.

J Gen Virol. 2009 Jun;90(Pt 6):1329-34. doi: 10.1099/vir.0.009332-0. Epub 2009 Mar 4.

PMID:
19264615
17.

Interferon sensitivity-determining region of nonstructural region 5A of hepatitis C virus genotype 1b correlates with serum alanine aminotransferase levels in chronic infection.

Yoshioka K, Ito H, Watanabe K, Yano M, Ishigami M, Mizutani T, Sasaki Y, Goto H.

J Viral Hepat. 2005 Mar;12(2):139-45.

PMID:
15720528
18.

Positive effect of the hepatitis C virus nonstructural 5A protein on viral multiplication.

Bonte D, François C, Castelain S, Wychowski C, Dubuisson J, Meurs EF, Duverlie G.

Arch Virol. 2004 Jul;149(7):1353-71. Epub 2004 Mar 17.

PMID:
15221536
19.

Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein.

Huang L, Hwang J, Sharma SD, Hargittai MR, Chen Y, Arnold JJ, Raney KD, Cameron CE.

J Biol Chem. 2005 Oct 28;280(43):36417-28. Epub 2005 Aug 25.

20.

Nonstructural protein 5A does not contribute to the resistance of hepatitis C virus replication to interferon alpha in cell culture.

Aus dem Siepen M, Lohmann V, Wiese M, Ross S, Roggendorf M, Viazov S.

Virology. 2005 Jun 5;336(2):131-6.

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