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Items: 1 to 20 of 166

1.

Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.

Phan AT, Kuryavyi V, Gaw HY, Patel DJ.

Nat Chem Biol. 2005 Aug;1(3):167-73. Epub 2005 Jul 17. Erratum in: Nat Chem Biol. 2005 Sep;1(4):234.

2.

Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure.

Seenisamy J, Bashyam S, Gokhale V, Vankayalapati H, Sun D, Siddiqui-Jain A, Streiner N, Shin-Ya K, White E, Wilson WD, Hurley LH.

J Am Chem Soc. 2005 Mar 9;127(9):2944-59.

PMID:
15740131
3.
4.

Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4.

Le HT, Miller MC, Buscaglia R, Dean WL, Holt PA, Chaires JB, Trent JO.

Org Biomol Chem. 2012 Dec 21;10(47):9393-404. doi: 10.1039/c2ob26504d. Epub 2012 Oct 29.

5.

An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution.

Dai J, Dexheimer TS, Chen D, Carver M, Ambrus A, Jones RA, Yang D.

J Am Chem Soc. 2006 Feb 1;128(4):1096-8.

6.

Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops.

Benabou S, Ferreira R, Aviñó A, González C, Lyonnais S, Solà M, Eritja R, Jaumot J, Gargallo R.

Biochim Biophys Acta. 2014 Jan;1840(1):41-52. doi: 10.1016/j.bbagen.2013.08.028. Epub 2013 Sep 6.

PMID:
24012973
7.

G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

Cogoi S, Xodo LE.

Nucleic Acids Res. 2006 May 10;34(9):2536-49. Print 2006.

8.

Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms.

Yamashita T, Uno T, Ishikawa Y.

Bioorg Med Chem. 2005 Apr 1;13(7):2423-30.

PMID:
15755644
9.

Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter.

Phan AT, Modi YS, Patel DJ.

J Am Chem Soc. 2004 Jul 21;126(28):8710-6.

10.

Nemorubicin and doxorubicin bind the G-quadruplex sequences of the human telomeres and of the c-MYC promoter element Pu22.

Scaglioni L, Mondelli R, Artali R, Sirtori FR, Mazzini S.

Biochim Biophys Acta. 2016 Jun;1860(6):1129-38. doi: 10.1016/j.bbagen.2016.02.011. Epub 2016 Feb 23.

PMID:
26922833
11.

Structure of the biologically relevant G-quadruplex in the c-MYC promoter.

Yang D, Hurley LH.

Nucleosides Nucleotides Nucleic Acids. 2006;25(8):951-68. Review.

PMID:
16901825
13.

Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element.

Hurley LH, Von Hoff DD, Siddiqui-Jain A, Yang D.

Semin Oncol. 2006 Aug;33(4):498-512. Review.

PMID:
16890804
14.

c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability.

Mathad RI, Hatzakis E, Dai J, Yang D.

Nucleic Acids Res. 2011 Nov 1;39(20):9023-33. doi: 10.1093/nar/gkr612. Epub 2011 Jul 27.

15.

(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex.

Zhang N, Phan AT, Patel DJ.

J Am Chem Soc. 2005 Dec 14;127(49):17277-85.

17.

Solution structure of a DNA quadruplex containing the fragile X syndrome triplet repeat.

Kettani A, Kumar RA, Patel DJ.

J Mol Biol. 1995 Dec 8;254(4):638-56.

PMID:
7500339
18.

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.

Siddiqui-Jain A, Grand CL, Bearss DJ, Hurley LH.

Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11593-8. Epub 2002 Aug 23.

19.
20.

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.

Dai J, Chen D, Jones RA, Hurley LH, Yang D.

Nucleic Acids Res. 2006;34(18):5133-44. Epub 2006 Sep 22.

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