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Items: 1 to 20 of 96

1.

Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation.

Cha YI, Kim SH, Sepich D, Buchanan FG, Solnica-Krezel L, DuBois RN.

Genes Dev. 2006 Jan 1;20(1):77-86.

2.

Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization.

Speirs CK, Jernigan KK, Kim SH, Cha YI, Lin F, Sepich DS, DuBois RN, Lee E, Solnica-Krezel L.

Development. 2010 Apr;137(8):1327-37. doi: 10.1242/dev.045971.

3.

Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome.

Kim JI, Lakshmikanthan V, Frilot N, Daaka Y.

Mol Cancer Res. 2010 Apr;8(4):569-77. doi: 10.1158/1541-7786.MCR-09-0511. Epub 2010 Mar 30.

4.

Prostaglandin E2 promotes wound-induced migration of intestinal subepithelial myofibroblasts via EP2, EP3, and EP4 prostanoid receptor activation.

Iwanaga K, Okada M, Murata T, Hori M, Ozaki H.

J Pharmacol Exp Ther. 2012 Mar;340(3):604-11. doi: 10.1124/jpet.111.189845. Epub 2011 Dec 2.

5.

The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells.

Cherukuri DP, Chen XB, Goulet AC, Young RN, Han Y, Heimark RL, Regan JW, Meuillet E, Nelson MA.

Exp Cell Res. 2007 Aug 15;313(14):2969-79. Epub 2007 Jun 22.

6.

Prostaglandin E2-EP4 receptor promotes endothelial cell migration via ERK activation and angiogenesis in vivo.

Rao R, Redha R, Macias-Perez I, Su Y, Hao C, Zent R, Breyer MD, Pozzi A.

J Biol Chem. 2007 Jun 8;282(23):16959-68. Epub 2007 Mar 31.

7.

PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes.

He Q, Harding P, LaPointe MC.

Am J Physiol Heart Circ Physiol. 2010 Jan;298(1):H136-43. doi: 10.1152/ajpheart.00251.2009. Epub 2009 Oct 30.

9.

Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis.

Oshima H, Popivanova BK, Oguma K, Kong D, Ishikawa TO, Oshima M.

Cancer Sci. 2011 Apr;102(4):713-9. doi: 10.1111/j.1349-7006.2011.01847.x. Epub 2011 Feb 2.

10.
11.

Microsomal prostaglandin E2 synthase 1 expression in basic calcium phosphate crystal-stimulated fibroblasts: role of prostaglandin E2 and the EP4 receptor.

Molloy ES, Morgan MP, Doherty GA, McDonnell B, O'Byrne J, Fitzgerald DJ, McCarthy GM.

Osteoarthritis Cartilage. 2009 May;17(5):686-92. doi: 10.1016/j.joca.2008.09.014. Epub 2008 Oct 17.

12.

Cyclooxygenase-2 derived PGE2 and PGI2 play an important role via EP2 and PPARdelta receptors in early steps of oil induced decidualization in mice.

Pakrasi PL, Jain AK.

Placenta. 2008 Jun;29(6):523-30. doi: 10.1016/j.placenta.2008.03.001. Epub 2008 Apr 14.

PMID:
18407349
13.
14.

Association between prostaglandin E receptor subtype EP4 overexpression and unstable phenotype in atherosclerotic plaques in human.

Cipollone F, Fazia ML, Iezzi A, Cuccurullo C, De Cesare D, Ucchino S, Spigonardo F, Marchetti A, Buttitta F, Paloscia L, Mascellanti M, Cuccurullo F, Mezzetti A.

Arterioscler Thromb Vasc Biol. 2005 Sep;25(9):1925-31. Epub 2005 Jul 14.

15.

Zebrafish gastrulation: cell movements, signals, and mechanisms.

Rohde LA, Heisenberg CP.

Int Rev Cytol. 2007;261:159-92. Review.

PMID:
17560282
17.

Bmp activity gradient regulates convergent extension during zebrafish gastrulation.

Myers DC, Sepich DS, Solnica-Krezel L.

Dev Biol. 2002 Mar 1;243(1):81-98.

18.

Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells.

Timoshenko AV, Xu G, Chakrabarti S, Lala PK, Chakraborty C.

Exp Cell Res. 2003 Oct 1;289(2):265-74.

PMID:
14499627
19.

Hypertonicity stimulates PGE2 signaling in the renal medulla by promoting EP3 and EP4 receptor expression.

Kim JA, Sheen MR, Lee SD, Jung JY, Kwon HM.

Kidney Int. 2009 Feb;75(3):278-84. doi: 10.1038/ki.2008.498. Epub 2008 Oct 8.

20.

Lipopolysaccharide stimulates the production of prostaglandin E2 and the receptor Ep4 in osteoblasts.

Shoji M, Tanabe N, Mitsui N, Tanaka H, Suzuki N, Takeichi O, Sugaya A, Maeno M.

Life Sci. 2006 Mar 20;78(17):2012-8. Epub 2005 Nov 14.

PMID:
16289620

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