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Items: 1 to 20 of 103

1.

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.

Zhu B, Zheng Y, Pham AD, Mandal SS, Erdjument-Bromage H, Tempst P, Reinberg D.

Mol Cell. 2005 Nov 23;20(4):601-11.

2.

The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p.

Wood A, Schneider J, Dover J, Johnston M, Shilatifard A.

J Biol Chem. 2003 Sep 12;278(37):34739-42. Epub 2003 Jul 21.

3.

The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination.

Hahn MA, Dickson KA, Jackson S, Clarkson A, Gill AJ, Marsh DJ.

Hum Mol Genet. 2012 Feb 1;21(3):559-68. doi: 10.1093/hmg/ddr490. Epub 2011 Oct 21.

PMID:
22021426
4.

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.

Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M.

Genes Dev. 2008 Oct 1;22(19):2664-76. doi: 10.1101/gad.1703008.

5.

The Bur1/Bur2 complex is required for histone H2B monoubiquitination by Rad6/Bre1 and histone methylation by COMPASS.

Wood A, Schneider J, Dover J, Johnston M, Shilatifard A.

Mol Cell. 2005 Nov 23;20(4):589-99.

6.

WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription.

Zhang F, Yu X.

Mol Cell. 2011 Feb 18;41(4):384-97. doi: 10.1016/j.molcel.2011.01.024.

7.

Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.

Li XS, Trojer P, Matsumura T, Treisman JE, Tanese N.

Mol Cell Biol. 2010 Apr;30(7):1673-88. doi: 10.1128/MCB.00540-09. Epub 2010 Jan 19.

8.

Histone H2B ubiquitylation is associated with elongating RNA polymerase II.

Xiao T, Kao CF, Krogan NJ, Sun ZW, Greenblatt JF, Osley MA, Strahl BD.

Mol Cell Biol. 2005 Jan;25(2):637-51.

9.

Histone H2B monoubiquitination: roles to play in human malignancy.

Cole AJ, Clifton-Bligh R, Marsh DJ.

Endocr Relat Cancer. 2015 Feb;22(1):T19-33. doi: 10.1530/ERC-14-0185. Epub 2014 Jun 2. Review.

10.

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.

Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA, Shilatifard A, Muir TW, Roeder RG.

Cell. 2009 May 1;137(3):459-71. doi: 10.1016/j.cell.2009.02.027.

11.

Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability.

Chernikova SB, Razorenova OV, Higgins JP, Sishc BJ, Nicolau M, Dorth JA, Chernikova DA, Kwok S, Brooks JD, Bailey SM, Game JC, Brown JM.

Cancer Res. 2012 Apr 15;72(8):2111-9. doi: 10.1158/0008-5472.CAN-11-2209. Epub 2012 Feb 21.

12.

Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia.

Wang E, Kawaoka S, Yu M, Shi J, Ni T, Yang W, Zhu J, Roeder RG, Vakoc CR.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3901-6. doi: 10.1073/pnas.1301045110. Epub 2013 Feb 14.

13.

Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS.

Lee JS, Shukla A, Schneider J, Swanson SK, Washburn MP, Florens L, Bhaumik SR, Shilatifard A.

Cell. 2007 Dec 14;131(6):1084-96.

14.

Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II.

Pavri R, Zhu B, Li G, Trojer P, Mandal S, Shilatifard A, Reinberg D.

Cell. 2006 May 19;125(4):703-17.

15.

Role of histone H2A ubiquitination in Polycomb silencing.

Wang H, Wang L, Erdjument-Bromage H, Vidal M, Tempst P, Jones RS, Zhang Y.

Nature. 2004 Oct 14;431(7010):873-8. Epub 2004 Sep 22.

PMID:
15386022
16.

Regulation of homologous recombination by RNF20-dependent H2B ubiquitination.

Nakamura K, Kato A, Kobayashi J, Yanagihara H, Sakamoto S, Oliveira DV, Shimada M, Tauchi H, Suzuki H, Tashiro S, Zou L, Komatsu K.

Mol Cell. 2011 Mar 4;41(5):515-28. doi: 10.1016/j.molcel.2011.02.002.

17.

Monoubiquitination of histone H2B is intrinsic to the Bre1 RING domain-Rad6 interaction and augmented by a second Rad6-binding site on Bre1.

Turco E, Gallego LD, Schneider M, Köhler A.

J Biol Chem. 2015 Feb 27;290(9):5298-310. doi: 10.1074/jbc.M114.626788. Epub 2014 Dec 29.

18.

Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B.

Foglizzo M, Middleton AJ, Day CL.

J Mol Biol. 2016 Oct 9;428(20):4073-4086. doi: 10.1016/j.jmb.2016.07.025. Epub 2016 Aug 25.

PMID:
27569044
19.

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast.

Sun ZW, Allis CD.

Nature. 2002 Jul 4;418(6893):104-8. Epub 2002 Jun 23.

PMID:
12077605
20.

RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression.

Shema E, Kim J, Roeder RG, Oren M.

Mol Cell. 2011 May 20;42(4):477-88. doi: 10.1016/j.molcel.2011.03.011.

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