Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 113

1.

Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2.

Tavazoie SF, Alvarez VA, Ridenour DA, Kwiatkowski DJ, Sabatini BL.

Nat Neurosci. 2005 Dec;8(12):1727-34. Epub 2005 Nov 6.

PMID:
16286931
2.

Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells.

Uhlmann EJ, Apicelli AJ, Baldwin RL, Burke SP, Bajenaru ML, Onda H, Kwiatkowski D, Gutmann DH.

Oncogene. 2002 Jun 6;21(25):4050-9.

3.

Antisense suppression of TSC1 gene product, hamartin, enhances neurite outgrowth in NGF-treated PC12h cells.

Floricel F, Higaki K, Maki H, Nanba E, Ninomiya H, Ohno K.

Brain Dev. 2007 Sep;29(8):502-9. Epub 2007 Mar 21.

PMID:
17376623
4.

Analysis of 65 tuberous sclerosis complex (TSC) patients by TSC2 DGGE, TSC1/TSC2 MLPA, and TSC1 long-range PCR sequencing, and report of 28 novel mutations.

Rendtorff ND, Bjerregaard B, Frödin M, Kjaergaard S, Hove H, Skovby F, Brøndum-Nielsen K, Schwartz M; Danish Tuberous Sclerosis Group.

Hum Mutat. 2005 Oct;26(4):374-83.

PMID:
16114042
5.

Enhanced episodic-like memory and kindling epilepsy in a rat model of tuberous sclerosis.

Waltereit R, Welzl H, Dichgans J, Lipp HP, Schmidt WJ, Weller M.

J Neurochem. 2006 Jan;96(2):407-13. Epub 2005 Nov 21.

6.

Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.

Zeng LH, Rensing NR, Zhang B, Gutmann DH, Gambello MJ, Wong M.

Hum Mol Genet. 2011 Feb 1;20(3):445-54. doi: 10.1093/hmg/ddq491. Epub 2010 Nov 9.

7.

Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease.

Astrinidis A, Henske EP.

Oncogene. 2005 Nov 14;24(50):7475-81. Review.

PMID:
16288294
8.

Developmental origin of subependymal giant cell astrocytoma in tuberous sclerosis complex.

Ess KC, Kamp CA, Tu BP, Gutmann DH.

Neurology. 2005 Apr 26;64(8):1446-9.

PMID:
15851742
9.

Generation of a conditional disruption of the Tsc2 gene.

Hernandez O, Way S, McKenna J 3rd, Gambello MJ.

Genesis. 2007 Feb;45(2):101-6.

PMID:
17245776
10.

Tsc2 null murine neuroepithelial cells are a model for human tuber giant cells, and show activation of an mTOR pathway.

Onda H, Crino PB, Zhang H, Murphey RD, Rastelli L, Gould Rothberg BE, Kwiatkowski DJ.

Mol Cell Neurosci. 2002 Dec;21(4):561-74.

PMID:
12504590
11.

Expression profiling in tuberous sclerosis complex (TSC) knockout mouse astrocytes to characterize human TSC brain pathology.

Ess KC, Uhlmann EJ, Li W, Li H, Declue JE, Crino PB, Gutmann DH.

Glia. 2004 Apr 1;46(1):28-40.

PMID:
14999811
12.

The tuberous sclerosis genes, TSC1 and TSC2, trigger different gene expression responses.

Rosner M, Freilinger A, Lubec G, Hengstschläger M.

Int J Oncol. 2005 Nov;27(5):1411-24.

PMID:
16211238
13.

Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex.

Sugiura H, Yasuda S, Katsurabayashi S, Kawano H, Endo K, Takasaki K, Iwasaki K, Ichikawa M, Kobayashi T, Hino O, Yamagata K.

Nat Commun. 2015 Apr 16;6:6842. doi: 10.1038/ncomms7842.

PMID:
25880340
14.

Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models.

Lee L, Sudentas P, Donohue B, Asrican K, Worku A, Walker V, Sun Y, Schmidt K, Albert MS, El-Hashemite N, Lader AS, Onda H, Zhang H, Kwiatkowski DJ, Dabora SL.

Genes Chromosomes Cancer. 2005 Mar;42(3):213-27.

PMID:
15578690
15.

The neurobiology of the tuberous sclerosis complex.

Marcotte L, Crino PB.

Neuromolecular Med. 2006;8(4):531-46. Review.

PMID:
17028374
16.

Mutational analysis of TSC1 and TSC2 in Korean patients with tuberous sclerosis complex.

Choi JE, Chae JH, Hwang YS, Kim KJ.

Brain Dev. 2006 Aug;28(7):440-6. Epub 2006 Mar 22.

PMID:
16554133
17.

Functional characterisation of the TSC1-TSC2 complex to assess multiple TSC2 variants identified in single families affected by tuberous sclerosis complex.

Nellist M, Sancak O, Goedbloed M, Adriaans A, Wessels M, Maat-Kievit A, Baars M, Dommering C, van den Ouweland A, Halley D.

BMC Med Genet. 2008 Feb 26;9:10. doi: 10.1186/1471-2350-9-10.

18.

A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma.

Wilson C, Idziaszczyk S, Parry L, Guy C, Griffiths DF, Lazda E, Bayne RA, Smith AJ, Sampson JR, Cheadle JP.

Hum Mol Genet. 2005 Jul 1;14(13):1839-50. Epub 2005 May 11.

PMID:
15888477
19.

Functional characterization of the TSC2 c.3598C>T (p.R1200W) missense mutation that co-segregates with tuberous sclerosis complex in mildly affected kindreds.

Wentink M, Nellist M, Hoogeveen-Westerveld M, Zonnenberg B, van der Kolk D, van Essen T, Park SM, Woods G, Cohn-Hokke P, Brussel W, Smeets E, Brooks A, Halley D, van den Ouweland A, Maat-Kievit A.

Clin Genet. 2012 May;81(5):453-61. doi: 10.1111/j.1399-0004.2011.01648.x. Epub 2011 Mar 10.

PMID:
21332470
20.

Neocortical hyperexcitability in a human case of tuberous sclerosis complex and mice lacking neuronal expression of TSC1.

Wang Y, Greenwood JS, Calcagnotto ME, Kirsch HE, Barbaro NM, Baraban SC.

Ann Neurol. 2007 Feb;61(2):139-52.

PMID:
17279540

Supplemental Content

Support Center