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Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms.

Arnesen T, Gromyko D, Horvli O, Fluge Ø, Lillehaug J, Varhaug JE.

Thyroid. 2005 Oct;15(10):1131-6.


Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.

Arnesen T, Anderson D, Baldersheim C, Lanotte M, Varhaug JE, Lillehaug JR.

Biochem J. 2005 Mar 15;386(Pt 3):433-43.


Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase.

Arnesen T, Betts MJ, Pendino F, Liberles DA, Anderson D, Caro J, Kong X, Varhaug JE, Lillehaug JR.

BMC Biochem. 2006 Apr 25;7:13.


Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex.

Arnesen T, Gromyko D, Pendino F, Ryningen A, Varhaug JE, Lillehaug JR.

Oncogene. 2006 Jul 20;25(31):4350-60. Epub 2006 Mar 6.


The protein acetyltransferase ARD1: a novel cancer drug target?

Arnesen T, Thompson PR, Varhaug JE, Lillehaug JR.

Curr Cancer Drug Targets. 2008 Nov;8(7):545-53. Review.


NATH, a novel gene overexpressed in papillary thyroid carcinomas.

Fluge Ø, Bruland O, Akslen LA, Varhaug JE, Lillehaug JR.

Oncogene. 2002 Aug 1;21(33):5056-68.


Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha.

Arnesen T, Kong X, Evjenth R, Gromyko D, Varhaug JE, Lin Z, Sang N, Caro J, Lillehaug JR.

FEBS Lett. 2005 Nov 21;579(28):6428-32. Epub 2005 Nov 2.


Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex.

Arnesen T, Anderson D, Torsvik J, Halseth HB, Varhaug JE, Lillehaug JR.

Gene. 2006 Apr 26;371(2):291-5. Epub 2006 Feb 28.


Depletion of the human Nα-terminal acetyltransferase A induces p53-dependent apoptosis and p53-independent growth inhibition.

Gromyko D, Arnesen T, Ryningen A, Varhaug JE, Lillehaug JR.

Int J Cancer. 2010 Dec 15;127(12):2777-89. doi: 10.1002/ijc.25275.


The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation.

Arnesen T, Starheim KK, Van Damme P, Evjenth R, Dinh H, Betts MJ, Ryningen A, Vandekerckhove J, Gevaert K, Anderson D.

Mol Cell Biol. 2010 Apr;30(8):1898-909. doi: 10.1128/MCB.01199-09. Epub 2010 Feb 12.


Purified recombinant hARD1 does not catalyse acetylation of Lys532 of HIF-1alpha fragments in vitro.

Murray-Rust TA, Oldham NJ, Hewitson KS, Schofield CJ.

FEBS Lett. 2006 Apr 3;580(8):1911-8. Epub 2006 Feb 17.


Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1alpha in tumor growth and metastasis.

Lee MN, Lee SN, Kim SH, Kim B, Jung BK, Seo JH, Park JH, Choi JH, Yim SH, Lee MR, Park JG, Yoo JY, Kim JH, Lee ST, Kim HM, Ryeom S, Kim KW, Oh GT.

J Natl Cancer Inst. 2010 Mar 17;102(6):426-42. doi: 10.1093/jnci/djq026. Epub 2010 Mar 1.


Involvement of N-acetyltransferase human in the cytotoxic activity of 5-fluorouracil.

Takubo K, Tsuchiya H, Kurimasa A, Arnesen T, Ryoke K, Shiota G.

Anticancer Drugs. 2009 Sep;20(8):668-75. doi: 10.1097/CAD.0b013e32832d5159.


Different subcellular localizations and functions of human ARD1 variants.

Seo JH, Park JH, Lee EJ, Kim KW.

Int J Oncol. 2015 Feb;46(2):701-7. doi: 10.3892/ijo.2014.2770. Epub 2014 Nov 21.


Autoacetylation regulates differentially the roles of ARD1 variants in tumorigenesis.

Seo JH, Park JH, Lee EJ, Vo TT, Choi H, Jang JK, Wee HJ, Ahn BJ, Cha JH, Shin MW, Kim KW.

Int J Oncol. 2015 Jan;46(1):99-106. doi: 10.3892/ijo.2014.2708. Epub 2014 Oct 17.


Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin.

Lim JH, Chun YS, Park JW.

Cancer Res. 2008 Jul 1;68(13):5177-84. doi: 10.1158/0008-5472.CAN-07-6234.


Characterization of ARD1 variants in mammalian cells.

Kim SH, Park JA, Kim JH, Lee JW, Seo JH, Jung BK, Chun KH, Jeong JW, Bae MK, Kim KW.

Biochem Biophys Res Commun. 2006 Feb 10;340(2):422-7. Epub 2005 Dec 15.


Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase.

Van Damme P, Evjenth R, Foyn H, Demeyer K, De Bock PJ, Lillehaug JR, Vandekerckhove J, Arnesen T, Gevaert K.

Mol Cell Proteomics. 2011 May;10(5):M110.004580. doi: 10.1074/mcp.M110.004580. Epub 2011 Mar 7.


Nuclear translocation of hARD1 contributes to proper cell cycle progression.

Park JH, Seo JH, Wee HJ, Vo TT, Lee EJ, Choi H, Cha JH, Ahn BJ, Shin MW, Bae SJ, Kim KW.

PLoS One. 2014 Aug 18;9(8):e105185. doi: 10.1371/journal.pone.0105185. eCollection 2014.

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