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Items: 1 to 20 of 305

1.

The role of the BRCA1 tumor suppressor in DNA double-strand break repair.

Zhang J, Powell SN.

Mol Cancer Res. 2005 Oct;3(10):531-9. Review.

2.

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Zhang J, Willers H, Feng Z, Ghosh JC, Kim S, Weaver DT, Chung JH, Powell SN, Xia F.

Mol Cell Biol. 2004 Jan;24(2):708-18.

3.

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining.

Zhuang J, Zhang J, Willers H, Wang H, Chung JH, van Gent DC, Hallahan DE, Powell SN, Xia F.

Cancer Res. 2006 Feb 1;66(3):1401-8.

4.

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA.

Anticancer Agents Med Chem. 2008 May;8(4):448-60. Review.

PMID:
18473729
5.

BRCA1 requirement for the fidelity of plasmid DNA double-strand break repair in cultured breast epithelial cells.

Thompson EG, Fares H, Dixon K.

Environ Mol Mutagen. 2012 Jan;53(1):32-43. doi: 10.1002/em.21674. Epub 2011 Dec 15.

PMID:
22170030
7.
8.

Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1.

Bau DT, Fu YP, Chen ST, Cheng TC, Yu JC, Wu PE, Shen CY.

Cancer Res. 2004 Jul 15;64(14):5013-9.

9.

BRCA1 contributes to cell cycle arrest and chemoresistance in response to the anticancer agent irofulven.

Wiltshire T, Senft J, Wang Y, Konat GW, Wenger SL, Reed E, Wang W.

Mol Pharmacol. 2007 Apr;71(4):1051-60. Epub 2007 Jan 17.

10.
11.

The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair.

Starita LM, Parvin JD.

Curr Opin Cell Biol. 2003 Jun;15(3):345-50. Review.

PMID:
12787778
12.

Brca1 controls homology-directed DNA repair.

Moynahan ME, Chiu JW, Koller BH, Jasin M.

Mol Cell. 1999 Oct;4(4):511-8.

13.

Identification of sequences that target BRCA1 to nuclear foci following alkylative DNA damage.

Au WW, Henderson BR.

Cell Signal. 2007 Sep;19(9):1879-92. Epub 2007 May 1.

PMID:
17531442
14.

BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1.

Dohrn L, Salles D, Siehler SY, Kaufmann J, Wiesmüller L.

Biochem J. 2012 Feb 1;441(3):919-26. doi: 10.1042/BJ20110314.

PMID:
22032289
15.

Role played by BRCA1 in regulating the cellular response to stress.

Gilmore PM, Quinn JE, Mullan PB, Andrews HN, McCabe N, Carty M, Kennedy RD, Harkin DP.

Biochem Soc Trans. 2003 Feb;31(Pt 1):257-62. Review.

PMID:
12546697
16.

BRCA1 gene in breast cancer.

Rosen EM, Fan S, Pestell RG, Goldberg ID.

J Cell Physiol. 2003 Jul;196(1):19-41. Review.

PMID:
12767038
17.

Deficient nonhomologous end-joining activity in cell-free extracts from Brca1-null fibroblasts.

Zhong Q, Boyer TG, Chen PL, Lee WH.

Cancer Res. 2002 Jul 15;62(14):3966-70.

18.

BRCA1 role in the mitigation of radiotoxicity and chromosomal instability through repair of clustered DNA lesions.

Hair JM, Terzoudi GI, Hatzi VI, Lehockey KA, Srivastava D, Wang W, Pantelias GE, Georgakilas AG.

Chem Biol Interact. 2010 Nov 5;188(2):350-8. doi: 10.1016/j.cbi.2010.03.046. Epub 2010 Apr 4. Review.

PMID:
20371364
19.

Direct DNA binding by Brca1.

Paull TT, Cortez D, Bowers B, Elledge SJ, Gellert M.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6086-91. Epub 2001 May 15.

20.

Caretaker Brca1: keeping the genome in the straight and narrow.

Yu V.

Breast Cancer Res. 2000;2(2):82-5. Epub 2000 Feb 7. Review.

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