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Items: 1 to 20 of 111

1.
2.

Membrane type-1 matrix metalloproteinase (MT1-MMP) exhibits an important intracellular cleavage function and causes chromosome instability.

Golubkov VS, Boyd S, Savinov AY, Chekanov AV, Osterman AL, Remacle A, Rozanov DV, Doxsey SJ, Strongin AY.

J Biol Chem. 2005 Jul 1;280(26):25079-86. Epub 2005 May 4.

3.

Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cells.

Golubkov VS, Chekanov AV, Savinov AY, Rozanov DV, Golubkova NV, Strongin AY.

Cancer Res. 2006 Nov 1;66(21):10460-5.

4.

O-glycosylation regulates autolysis of cellular membrane type-1 matrix metalloproteinase (MT1-MMP).

Remacle AG, Chekanov AV, Golubkov VS, Savinov AY, Rozanov DV, Strongin AY.

J Biol Chem. 2006 Jun 23;281(25):16897-905. Epub 2006 Apr 20.

5.

Furin regulates the intracellular activation and the uptake rate of cell surface-associated MT1-MMP.

Remacle AG, Rozanov DV, Fugere M, Day R, Strongin AY.

Oncogene. 2006 Sep 14;25(41):5648-55. Epub 2006 Apr 24.

PMID:
16636666
6.

An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinase.

Ratnikov BI, Rozanov DV, Postnova TI, Baciu PG, Zhang H, DiScipio RG, Chestukhina GG, Smith JW, Deryugina EI, Strongin AY.

J Biol Chem. 2002 Mar 1;277(9):7377-85. Epub 2001 Dec 10.

7.

Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells.

Jiang WG, Davies G, Martin TA, Parr C, Watkins G, Mason MD, Mansel RE.

Int J Mol Med. 2006 Apr;17(4):583-90.

PMID:
16525713
8.

Activation of matrix metalloproteinase-2 (MMP-2) by membrane type 1 matrix metalloproteinase through an artificial receptor for proMMP-2 generates active MMP-2.

Nishida Y, Miyamori H, Thompson EW, Takino T, Endo Y, Sato H.

Cancer Res. 2008 Nov 1;68(21):9096-104. doi: 10.1158/0008-5472.CAN-08-2522.

9.

The transmembrane domain is essential for the microtubular trafficking of membrane type-1 matrix metalloproteinase (MT1-MMP).

Remacle AG, Rozanov DV, Baciu PC, Chekanov AV, Golubkov VS, Strongin AY.

J Cell Sci. 2005 Nov 1;118(Pt 21):4975-84. Epub 2005 Oct 11.

10.

Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells.

Egawa N, Koshikawa N, Tomari T, Nabeshima K, Isobe T, Seiki M.

J Biol Chem. 2006 Dec 8;281(49):37576-85. Epub 2006 Oct 18.

11.

Increased aggressiveness of human prostate PC-3 tumor cells expressing cell surface localized membrane type-1 matrix metalloproteinase (MT1-MMP).

Wang X, Wilson MJ, Slaton JW, Sinha AA, Ewing SL, Pei D.

J Androl. 2009 May-Jun;30(3):259-74. doi: 10.2164/jandrol.108.006494. Epub 2009 Jan 8.

12.

Prointegrin maturation follows rapid trafficking and processing of MT1-MMP in Furin-Negative Colon Carcinoma LoVo Cells.

Deryugina EI, Ratnikov BI, Yu Q, Baciu PC, Rozanov DV, Strongin AY.

Traffic. 2004 Aug;5(8):627-41.

13.

Fibroblast-derived MT1-MMP promotes tumor progression in vitro and in vivo.

Zhang W, Matrisian LM, Holmbeck K, Vick CC, Rosenthal EL.

BMC Cancer. 2006 Mar 6;6:52.

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Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.

Osenkowski P, Meroueh SO, Pavel D, Mobashery S, Fridman R.

J Biol Chem. 2005 Jul 15;280(28):26160-8. Epub 2005 May 18.

17.

Expression of matrix metalloproteinase (MMP)-2, MMP-9, MMP-13, and MT1-MMP in skin tumors of human papillomavirus type 8 transgenic mice.

Akgül B, Pfefferle R, Marcuzzi GP, Zigrino P, Krieg T, Pfister H, Mauch C.

Exp Dermatol. 2006 Jan;15(1):35-42.

PMID:
16364029
18.

Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain.

Koshikawa N, Minegishi T, Sharabi A, Quaranta V, Seiki M.

J Biol Chem. 2005 Jan 7;280(1):88-93. Epub 2004 Nov 3.

19.

Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cells.

Rozanov DV, Deryugina EI, Monosov EZ, Marchenko ND, Strongin AY.

Exp Cell Res. 2004 Feb 1;293(1):81-95.

PMID:
14729059
20.

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