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Items: 1 to 20 of 359

1.

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J.

Nature. 2005 Oct 20;437(7062):1167-72. Epub 2005 Sep 21.

PMID:
16177806
2.

Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.

Paz S, Sun Q, Nakhaei P, Romieu-Mourez R, Goubau D, Julkunen I, Lin R, Hiscott J.

Cell Mol Biol (Noisy-le-grand). 2006 May 15;52(1):17-28.

PMID:
16914100
3.

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction.

Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishii KJ, Takeuchi O, Akira S.

Nat Immunol. 2005 Oct;6(10):981-8. Epub 2005 Aug 28.

PMID:
16127453
4.

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression.

Kaukinen P, Sillanpää M, Kotenko S, Lin R, Hiscott J, Melén K, Julkunen I.

Virol J. 2006 Sep 1;3:66.

5.

Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense.

Johnson CL, Owen DM, Gale M Jr.

J Biol Chem. 2007 Apr 6;282(14):10792-803. Epub 2007 Feb 8.

6.

Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity.

Nitta S, Sakamoto N, Nakagawa M, Kakinuma S, Mishima K, Kusano-Kitazume A, Kiyohashi K, Murakawa M, Nishimura-Sakurai Y, Azuma S, Tasaka-Fujita M, Asahina Y, Yoneyama M, Fujita T, Watanabe M.

Hepatology. 2013 Jan;57(1):46-58. doi: 10.1002/hep.26017.

PMID:
22911572
7.
8.

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon.

Breiman A, Grandvaux N, Lin R, Ottone C, Akira S, Yoneyama M, Fujita T, Hiscott J, Meurs EF.

J Virol. 2005 Apr;79(7):3969-78.

9.

GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS.

Chen Z, Benureau Y, Rijnbrand R, Yi J, Wang T, Warter L, Lanford RE, Weinman SA, Lemon SM, Martin A, Li K.

J Virol. 2007 Jan;81(2):964-76. Epub 2006 Nov 8.

10.

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential.

Oshiumi H, Sakai K, Matsumoto M, Seya T.

Eur J Immunol. 2010 Apr;40(4):940-8. doi: 10.1002/eji.200940203.

11.

TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1.

Lee Y, Song B, Park C, Kwon KS.

PLoS One. 2013 May 13;8(5):e63255. doi: 10.1371/journal.pone.0063255. Print 2013.

12.

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

Lin R, Yang L, Nakhaei P, Sun Q, Sharif-Askari E, Julkunen I, Hiscott J.

J Biol Chem. 2006 Jan 27;281(4):2095-103. Epub 2005 Nov 23.

13.

A Src-family-tyrosine kinase, Lyn, is required for efficient IFN-β expression in pattern recognition receptor, RIG-I, signal pathway by interacting with IPS-1.

Lim YJ, Koo JE, Hong EH, Park ZY, Lim KM, Bae ON, Lee JY.

Cytokine. 2015 Mar;72(1):63-70. doi: 10.1016/j.cyto.2014.12.008. Epub 2015 Jan 10.

PMID:
25585356
14.

Functional characterization of domains of IPS-1 using an inducible oligomerization system.

Takamatsu S, Onoguchi K, Onomoto K, Narita R, Takahasi K, Ishidate F, Fujiwara TK, Yoneyama M, Kato H, Fujita T.

PLoS One. 2013;8(1):e53578. doi: 10.1371/journal.pone.0053578. Epub 2013 Jan 7.

15.

Restoration of the activated Rig-I pathway in hepatitis C virus (HCV) replicon cells by HCV protease, polymerase, and NS5A inhibitors in vitro at clinically relevant concentrations.

Kalkeri G, Lin C, Gopilan J, Sloan K, Rijnbrand R, Kwong AD.

Antimicrob Agents Chemother. 2013 Sep;57(9):4417-26. doi: 10.1128/AAC.00399-13. Epub 2013 Jul 8.

16.

Hepatitis A virus suppresses RIG-I-mediated IRF-3 activation to block induction of beta interferon.

Fensterl V, Grotheer D, Berk I, Schlemminger S, Vallbracht A, Dotzauer A.

J Virol. 2005 Sep;79(17):10968-77.

17.

Hepatitis C virus variants resistant to macrocyclic NS3-4A inhibitors subvert IFN-β induction by efficient MAVS cleavage.

Welsch C, Haselow K, Gouttenoire J, Schneider M, Morikawa K, Martinez Y, Susser S, Sarrazin C, Zeuzem S, Antes I, Moradpour D, Lange CM.

J Hepatol. 2015 Apr;62(4):779-84. doi: 10.1016/j.jhep.2014.11.009. Epub 2014 Nov 21.

PMID:
25463536
18.

The DEAH-box RNA helicase DHX15 activates NF-κB and MAPK signaling downstream of MAVS during antiviral responses.

Mosallanejad K, Sekine Y, Ishikura-Kinoshita S, Kumagai K, Nagano T, Matsuzawa A, Takeda K, Naguro I, Ichijo H.

Sci Signal. 2014 Apr 29;7(323):ra40. doi: 10.1126/scisignal.2004841.

PMID:
24782566
19.

RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium.

Broquet AH, Hirata Y, McAllister CS, Kagnoff MF.

J Immunol. 2011 Feb 1;186(3):1618-26. doi: 10.4049/jimmunol.1002862. Epub 2010 Dec 27.

20.

VISA is an adapter protein required for virus-triggered IFN-beta signaling.

Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB.

Mol Cell. 2005 Sep 16;19(6):727-40.

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