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Items: 1 to 20 of 185

1.

Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe.

Niida H, Tsuge S, Katsuno Y, Konishi A, Takeda N, Nakanishi M.

J Biol Chem. 2005 Nov 25;280(47):39246-52. Epub 2005 Sep 13.

2.

Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis.

Imreh G, Norberg HV, Imreh S, Zhivotovsky B.

J Cell Sci. 2011 Sep 1;124(Pt 17):2951-63. doi: 10.1242/jcs.081612. Erratum in: J Cell Sci. 2016 May 1;129(9):1950.

3.

Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage.

Tsvetkov L, Stern DF.

Cell Cycle. 2005 Jan;4(1):166-71. Epub 2005 Jan 5.

PMID:
15611664
4.

Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.

Lee HJ, Hwang HI, Jang YJ.

Cell Cycle. 2010 Jun 15;9(12):2389-98. Epub 2010 Jun 15.

PMID:
20581453
5.

The human decatenation checkpoint.

Deming PB, Cistulli CA, Zhao H, Graves PR, Piwnica-Worms H, Paules RS, Downes CS, Kaufmann WK.

Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12044-9. Epub 2001 Oct 2.

6.

Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells.

Bork U, Lee WK, Kuchler A, Dittmar T, Thévenod F.

Am J Physiol Renal Physiol. 2010 Feb;298(2):F255-65. doi: 10.1152/ajprenal.00273.2009. Epub 2009 Nov 18.

7.

Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.

Demidova AR, Aau MY, Zhuang L, Yu Q.

J Biol Chem. 2009 Feb 13;284(7):4132-9. doi: 10.1074/jbc.M808118200. Epub 2008 Dec 7.

8.

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.

Pabla N, Huang S, Mi QS, Daniel R, Dong Z.

J Biol Chem. 2008 Mar 7;283(10):6572-83. Epub 2007 Dec 27. Erratum in: J Biol Chem. 2008 May 30;283(22):15512.

9.

DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells.

Zhang W, Peng G, Lin SY, Zhang P.

J Biol Chem. 2011 Oct 14;286(41):35899-905. doi: 10.1074/jbc.M111.267690. Epub 2011 Aug 30.

10.

Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.

Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R.

Carcinogenesis. 2005 Nov;26(11):1978-87. Epub 2005 Jun 23.

PMID:
15975956
11.
12.

Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase.

McNeely S, Conti C, Sheikh T, Patel H, Zabludoff S, Pommier Y, Schwartz G, Tse A.

Cell Cycle. 2010 Mar 1;9(5):995-1004. Epub 2010 Mar 14.

PMID:
20160494
13.

RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage.

Anantha RW, Sokolova E, Borowiec JA.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12903-8. doi: 10.1073/pnas.0803001105. Epub 2008 Aug 22.

14.

The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.

Castedo M, Perfettini JL, Roumier T, Yakushijin K, Horne D, Medema R, Kroemer G.

Oncogene. 2004 May 27;23(25):4353-61.

PMID:
15048074
15.

Regulation of mitotic entry by microcephalin and its overlap with ATR signalling.

Alderton GK, Galbiati L, Griffith E, Surinya KH, Neitzel H, Jackson AP, Jeggo PA, O'Driscoll M.

Nat Cell Biol. 2006 Jul;8(7):725-33. Epub 2006 Jun 18.

PMID:
16783362
16.

DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.

Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, Poon RY.

Mol Biol Cell. 2003 Oct;14(10):3989-4002. Epub 2003 Jul 25.

17.

Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling.

Jurvansuu J, Fragkos M, Ingemarsdotter C, Beard P.

J Mol Biol. 2007 Sep 14;372(2):397-406. Epub 2007 Jul 3.

PMID:
17663993
18.

Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage.

Nabha SM, Mohammad RM, Dandashi MH, Coupaye-Gerard B, Aboukameel A, Pettit GR, Al-Katib AM.

Clin Cancer Res. 2002 Aug;8(8):2735-41.

19.
20.

Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.

Kulkarni A, Das KC.

Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L998-L1006. doi: 10.1152/ajplung.00004.2008. Epub 2008 Mar 14.

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