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Items: 1 to 20 of 105


RalA and RalB: antagonistic relatives in cancer cell migration.

Oxford G, Owens CR, Titus BJ, Foreman TL, Herlevsen MC, Smith SC, Theodorescu D.

Cancer Res. 2005 Aug 15;65(16):7111-20.


Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.

Lim KH, O'Hayer K, Adam SJ, Kendall SD, Campbell PM, Der CJ, Counter CM.

Curr Biol. 2006 Dec 19;16(24):2385-94.


Involvement of RhoA and RalB in geranylgeranyltransferase I inhibitor-mediated inhibition of proliferation and migration of human oral squamous cell carcinoma cells.

Hamada M, Miki T, Iwai S, Shimizu H, Yura Y.

Cancer Chemother Pharmacol. 2011 Sep;68(3):559-69. doi: 10.1007/s00280-010-1520-9.


Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.

Peschard P, McCarthy A, Leblanc-Dominguez V, Yeo M, Guichard S, Stamp G, Marshall CJ.

Curr Biol. 2012 Nov 6;22(21):2063-8. doi: 10.1016/j.cub.2012.09.013.


Phosphorylation of RalB is important for bladder cancer cell growth and metastasis.

Wang H, Owens C, Chandra N, Conaway MR, Brautigan DL, Theodorescu D.

Cancer Res. 2010 Nov 1;70(21):8760-9. doi: 10.1158/0008-5472.CAN-10-0952.


Expression of ral GTPases, their effectors, and activators in human bladder cancer.

Smith SC, Oxford G, Baras AS, Owens C, Havaleshko D, Brautigan DL, Safo MK, Theodorescu D.

Clin Cancer Res. 2007 Jul 1;13(13):3803-13.


Activation of RalA is critical for Ras-induced tumorigenesis of human cells.

Lim KH, Baines AT, Fiordalisi JJ, Shipitsin M, Feig LA, Cox AD, Der CJ, Counter CM.

Cancer Cell. 2005 Jun;7(6):533-45.


RalBP1 is necessary for metastasis of human cancer cell lines.

Wu Z, Owens C, Chandra N, Popovic K, Conaway M, Theodorescu D.

Neoplasia. 2010 Dec;12(12):1003-12.


The role of Ral A in epidermal growth factor receptor-regulated cell motility.

Gildea JJ, Harding MA, Seraj MJ, Gulding KM, Theodorescu D.

Cancer Res. 2002 Feb 15;62(4):982-5.


The metastasis-associated gene CD24 is regulated by Ral GTPase and is a mediator of cell proliferation and survival in human cancer.

Smith SC, Oxford G, Wu Z, Nitz MD, Conaway M, Frierson HF, Hampton G, Theodorescu D.

Cancer Res. 2006 Feb 15;66(4):1917-22.


Expression profiling of Ral-depleted bladder cancer cells identifies RREB-1 as a novel transcriptional Ral effector.

Oxford G, Smith SC, Hampton G, Theodorescu D.

Oncogene. 2007 Nov 1;26(50):7143-52.


Ral isoforms are implicated in Fc gamma R-mediated phagocytosis: activation of phospholipase D by RalA.

Corrotte M, Nyguyen AP, Harlay ML, Vitale N, Bader MF, Grant NJ.

J Immunol. 2010 Sep 1;185(5):2942-50. doi: 10.4049/jimmunol.0903138.


Immunodetection of ralA and ralB GTP-binding proteins in various rat tissues and platelets.

Bhullar RP, Yang S.

Mol Cell Biochem. 1998 Feb;179(1-2):49-55.


RalA and RalB function as the critical GTP sensors for GTP-dependent exocytosis.

Li G, Han L, Chou TC, Fujita Y, Arunachalam L, Xu A, Wong A, Chiew SK, Wan Q, Wang L, Sugita S.

J Neurosci. 2007 Jan 3;27(1):190-202.


The Small GTPase RalA controls exocytosis of large dense core secretory granules by interacting with ARF6-dependent phospholipase D1.

Vitale N, Mawet J, Camonis J, Regazzi R, Bader MF, Chasserot-Golaz S.

J Biol Chem. 2005 Aug 19;280(33):29921-8.


Different metastasis promotive potency of small G-proteins RalA and RalB in in vivo hamster tumor model.

Rybko VA, Knizhnik AV, Komelkov AV, Aushev VN, Trukhanova LS, Tchevkina EM.

Cancer Cell Int. 2011 Jun 29;11(1):22. doi: 10.1186/1475-2867-11-22.


Characterization of RalB-Sec5-TBK1 function in human oncogenesis.

Chien Y, White MA.

Methods Enzymol. 2008;438:321-9. doi: 10.1016/S0076-6879(07)38022-1.


Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation.

Kidd AR 3rd, Snider JL, Martin TD, Graboski SF, Der CJ, Cox AD.

Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):205-12. doi: 10.1016/j.ijrobp.2010.03.023.

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