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Items: 1 to 20 of 108

1.

Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes.

Pérez-Morga D, Vanhollebeke B, Paturiaux-Hanocq F, Nolan DP, Lins L, Homblé F, Vanhamme L, Tebabi P, Pays A, Poelvoorde P, Jacquet A, Brasseur R, Pays E.

Science. 2005 Jul 15;309(5733):469-72.

2.

Apolipoprotein L-I is the trypanosome lytic factor of human serum.

Vanhamme L, Paturiaux-Hanocq F, Poelvoorde P, Nolan DP, Lins L, Van Den Abbeele J, Pays A, Tebabi P, Van Xong H, Jacquet A, Moguilevsky N, Dieu M, Kane JP, De Baetselier P, Brasseur R, Pays E.

Nature. 2003 Mar 6;422(6927):83-7.

PMID:
12621437
3.

C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.

Lecordier L, Vanhollebeke B, Poelvoorde P, Tebabi P, Paturiaux-Hanocq F, Andris F, Lins L, Pays E.

PLoS Pathog. 2009 Dec;5(12):e1000685. doi: 10.1371/journal.ppat.1000685. Epub 2009 Dec 4.

4.

The lysosomal targeting and intracellular metabolism of trypanosome lytic factor by Trypanosoma brucei brucei.

Shimamura M, Hager KM, Hajduk SL.

Mol Biochem Parasitol. 2001 Jul;115(2):227-37.

PMID:
11420109
5.

Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: relevance to trypanosome lysis.

Thomson R, Finkelstein A.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2894-9. doi: 10.1073/pnas.1421953112. Epub 2015 Feb 17.

6.

The trypanosome lytic factor of human serum and the molecular basis of sleeping sickness.

Vanhamme L, Pays E.

Int J Parasitol. 2004 Jul;34(8):887-98. Review.

PMID:
15217727
7.

Trypanosome lytic factor, a subclass of high-density lipoprotein, forms cation-selective pores in membranes.

Molina-Portela Mdel P, Lugli EB, Recio-Pinto E, Raper J.

Mol Biochem Parasitol. 2005 Dec;144(2):218-26. Epub 2005 Sep 19.

PMID:
16202458
8.

The function of apolipoproteins L.

Vanhollebeke B, Pays E.

Cell Mol Life Sci. 2006 Sep;63(17):1937-44. Review.

PMID:
16847577
9.

African trypanosomes: intracellular trafficking of host defense molecules.

Shiflett AM, Faulkner SD, Cotlin LF, Widener J, Stephens N, Hajduk SL.

J Eukaryot Microbiol. 2007 Jan-Feb;54(1):18-21.

PMID:
17300512
10.

Haptoglobin-related protein mediates trypanosome lytic factor binding to trypanosomes.

Drain J, Bishop JR, Hajduk SL.

J Biol Chem. 2001 Aug 10;276(32):30254-60. Epub 2001 May 14.

11.

Insight into the mechanism of trypanosome lytic factor-1 killing of Trypanosoma brucei brucei.

Bishop JR, Shimamura M, Hajduk SL.

Mol Biochem Parasitol. 2001 Nov;118(1):33-40.

PMID:
11704271
12.

Membrane permeabilization by trypanosome lytic factor, a cytolytic human high density lipoprotein.

Harrington JM, Howell S, Hajduk SL.

J Biol Chem. 2009 May 15;284(20):13505-12. doi: 10.1074/jbc.M900151200. Epub 2009 Mar 26.

13.

The C-terminal half of the colicin A pore-forming domain is active in vivo and in vitro.

Nardi A, Slatin SL, Baty D, Duché D.

J Mol Biol. 2001 Apr 13;307(5):1293-303.

PMID:
11292342
14.

Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1.

Vanwalleghem G, Fontaine F, Lecordier L, Tebabi P, Klewe K, Nolan DP, Yamaryo-Botté Y, Botté C, Kremer A, Burkard GS, Rassow J, Roditi I, Pérez-Morga D, Pays E.

Nat Commun. 2015 Aug 26;6:8078. doi: 10.1038/ncomms9078.

15.

Human serum lyses Trypanosoma brucei by triggering uncontrolled swelling of the parasite lysosome.

Vanhollebeke B, Lecordier L, Perez-Morga D, Amiguet-Vercher A, Pays E.

J Eukaryot Microbiol. 2007 Sep-Oct;54(5):448-51.

PMID:
17910690
16.

Distinct roles of haptoglobin-related protein and apolipoprotein L-I in trypanolysis by human serum.

Vanhollebeke B, Nielsen MJ, Watanabe Y, Truc P, Vanhamme L, Nakajima K, Moestrup SK, Pays E.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4118-23. Epub 2007 Feb 26.

17.

Trypanosome Lytic Factor-1 Initiates Oxidation-stimulated Osmotic Lysis of Trypanosoma brucei brucei.

Greene AS, Hajduk SL.

J Biol Chem. 2016 Feb 5;291(6):3063-75. doi: 10.1074/jbc.M115.680371. Epub 2015 Dec 8.

18.

Topology of the amphipathic helices of the colicin A pore-forming domain in E. coli lipid membranes studied by pulse EPR.

Böhme S, Padmavathi PV, Holterhues J, Ouchni F, Klare JP, Steinhoff HJ.

Phys Chem Chem Phys. 2009 Aug 21;11(31):6770-7. doi: 10.1039/b907117m. Epub 2009 Jul 7.

PMID:
19639151
19.

Distinct roles of apolipoprotein components within the trypanosome lytic factor complex revealed in a novel transgenic mouse model.

Molina-Portela MP, Samanovic M, Raper J.

J Exp Med. 2008 Aug 4;205(8):1721-8. doi: 10.1084/jem.20071463. Epub 2008 Jul 7.

20.

Characterization of primate trypanosome lytic factors.

Lugli EB, Pouliot M, Portela Mdel P, Loomis MR, Raper J.

Mol Biochem Parasitol. 2004 Nov;138(1):9-20.

PMID:
15500911

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