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Items: 1 to 20 of 109

1.

New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions.

Hunter CA.

Nat Rev Immunol. 2005 Jul;5(7):521-31. Review.

PMID:
15999093
2.

Stepwise regulation of TH1 responses in autoimmunity: IL-12-related cytokines and their receptors.

Becker C, Wirtz S, Neurath MF.

Inflamm Bowel Dis. 2005 Aug;11(8):755-64. Review.

PMID:
16043992
3.

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.

Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD.

Nature. 2003 Feb 13;421(6924):744-8.

PMID:
12610626
4.

Pathophysiology of interleukin-23 in experimental autoimmune encephalomyelitis.

Touil T, Fitzgerald D, Zhang GX, Rostami AM, Gran B.

Drug News Perspect. 2006 Mar;19(2):77-83. Review.

PMID:
16628262
5.

Interleukin-12 and the regulation of innate resistance and adaptive immunity.

Trinchieri G.

Nat Rev Immunol. 2003 Feb;3(2):133-46. Review.

PMID:
12563297
6.

IL-23 and IL-27: new members of the growing family of IL-12-related cytokines with important implications for therapeutics.

Cordoba-Rodriguez R, Frucht DM.

Expert Opin Biol Ther. 2003 Aug;3(5):715-23. Review.

PMID:
12880372
7.

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation.

Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T, Kastelein RA, Cua DJ.

J Exp Med. 2005 Jan 17;201(2):233-40.

8.

Human dendritic cells following Aspergillus fumigatus infection express the CCR7 receptor and a differential pattern of interleukin-12 (IL-12), IL-23, and IL-27 cytokines, which lead to a Th1 response.

Gafa V, Lande R, Gagliardi MC, Severa M, Giacomini E, Remoli ME, Nisini R, Ramoni C, Di Francesco P, Aldebert D, Grillot R, Coccia EM.

Infect Immun. 2006 Mar;74(3):1480-9.

9.

IL-23 enhances the inflammatory cell response in Cryptococcus neoformans infection and induces a cytokine pattern distinct from IL-12.

Kleinschek MA, Muller U, Brodie SJ, Stenzel W, Kohler G, Blumenschein WM, Straubinger RK, McClanahan T, Kastelein RA, Alber G.

J Immunol. 2006 Jan 15;176(2):1098-106.

10.

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells.

Hoeve MA, Savage ND, de Boer T, Langenberg DM, de Waal Malefyt R, Ottenhoff TH, Verreck FA.

Eur J Immunol. 2006 Mar;36(3):661-70.

11.

Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation.

Gutcher I, Urich E, Wolter K, Prinz M, Becher B.

Nat Immunol. 2006 Sep;7(9):946-53. Epub 2006 Aug 13.

12.
13.

IL-12 and IL-23: master regulators of innate and adaptive immunity.

Langrish CL, McKenzie BS, Wilson NJ, de Waal Malefyt R, Kastelein RA, Cua DJ.

Immunol Rev. 2004 Dec;202:96-105. Review.

PMID:
15546388
14.

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation.

Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, Sedgwick JD, Cua DJ.

J Exp Med. 2003 Dec 15;198(12):1951-7. Epub 2003 Dec 8.

15.

T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17.

Rangachari M, Mauermann N, Marty RR, Dirnhofer S, Kurrer MO, Komnenovic V, Penninger JM, Eriksson U.

J Exp Med. 2006 Aug 7;203(8):2009-19. Epub 2006 Jul 31.

16.

Gene therapy using IL 12 family members in infection, auto immunity, and cancer.

Waldner MJ, Neurath MF.

Curr Gene Ther. 2009 Aug;9(4):239-47. Review.

PMID:
19534655
17.

Notch regulates IL-10 production by T helper 1 cells.

Rutz S, Janke M, Kassner N, Hohnstein T, Krueger M, Scheffold A.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3497-502. doi: 10.1073/pnas.0712102105. Epub 2008 Feb 21.

18.

Novel IL-12 family members shed light on the orchestration of Th1 responses.

Brombacher F, Kastelein RA, Alber G.

Trends Immunol. 2003 Apr;24(4):207-12. Review.

PMID:
12697453
19.

Visualization of IL-12/23p40 in vivo reveals immunostimulatory dendritic cell migrants that promote Th1 differentiation.

Reinhardt RL, Hong S, Kang SJ, Wang ZE, Locksley RM.

J Immunol. 2006 Aug 1;177(3):1618-27.

20.

A unique role for IL-23 in promoting cellular immunity.

Lankford CS, Frucht DM.

J Leukoc Biol. 2003 Jan;73(1):49-56. Review.

PMID:
12525561

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