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Items: 1 to 20 of 65

1.

Recruitment of the human TREX complex to mRNA during splicing.

Masuda S, Das R, Cheng H, Hurt E, Dorman N, Reed R.

Genes Dev. 2005 Jul 1;19(13):1512-7.

2.

The human TREX-2 complex is stably associated with the nuclear pore basket.

Umlauf D, Bonnet J, Waharte F, Fournier M, Stierle M, Fischer B, Brino L, Devys D, Tora L.

J Cell Sci. 2013 Jun 15;126(Pt 12):2656-67. doi: 10.1242/jcs.118000. Epub 2013 Apr 16.

3.

Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA.

Chi B, Wang Q, Wu G, Tan M, Wang L, Shi M, Chang X, Cheng H.

Nucleic Acids Res. 2013 Jan;41(2):1294-306. doi: 10.1093/nar/gks1188. Epub 2012 Dec 7.

4.

TREX is a conserved complex coupling transcription with messenger RNA export.

Strässer K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondón AG, Aguilera A, Struhl K, Reed R, Hurt E.

Nature. 2002 May 16;417(6886):304-8. Epub 2002 Apr 28.

PMID:
11979277
5.

Human mRNA export machinery recruited to the 5' end of mRNA.

Cheng H, Dufu K, Lee CS, Hsu JL, Dias A, Reed R.

Cell. 2006 Dec 29;127(7):1389-400.

6.

Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation.

Rondón AG, Jimeno S, García-Rubio M, Aguilera A.

J Biol Chem. 2003 Oct 3;278(40):39037-43. Epub 2003 Jul 18.

7.

A role for TREX components in the release of spliced mRNA from nuclear speckle domains.

Dias AP, Dufu K, Lei H, Reed R.

Nat Commun. 2010 Oct 19;1:97. doi: 10.1038/ncomms1103.

8.

Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.

Boyne JR, Colgan KJ, Whitehouse A.

PLoS Pathog. 2008 Oct;4(10):e1000194. doi: 10.1371/journal.ppat.1000194. Epub 2008 Oct 31.

9.

Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex.

Hurt E, Luo MJ, Röther S, Reed R, Strässer K.

Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1858-62. Epub 2004 Feb 9.

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11.

Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11.

Johnson SA, Cubberley G, Bentley DL.

Mol Cell. 2009 Jan 30;33(2):215-26. doi: 10.1016/j.molcel.2008.12.007. Epub 2008 Dec 24.

12.

The interface between transcription and mRNP export: from THO to THSC/TREX-2.

Rondón AG, Jimeno S, Aguilera A.

Biochim Biophys Acta. 2010 Aug;1799(8):533-8. doi: 10.1016/j.bbagrm.2010.06.002. Epub 2010 Jun 19. Review.

PMID:
20601280
13.

Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly.

Luo ML, Zhou Z, Magni K, Christoforides C, Rappsilber J, Mann M, Reed R.

Nature. 2001 Oct 11;413(6856):644-7.

PMID:
11675789
14.
15.

Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells.

Listerman I, Sapra AK, Neugebauer KM.

Nat Struct Mol Biol. 2006 Sep;13(9):815-22. Epub 2006 Aug 20.

PMID:
16921380
16.

ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex.

Dufu K, Livingstone MJ, Seebacher J, Gygi SP, Wilson SA, Reed R.

Genes Dev. 2010 Sep 15;24(18):2043-53. doi: 10.1101/gad.1898610.

17.

The yeast THO complex forms a 5-subunit assembly that directly interacts with active chromatin.

Gewartowski K, Cuéllar J, Dziembowski A, Valpuesta JM.

Bioarchitecture. 2012 Jul-Aug;2(4):134-7. doi: 10.4161/bioa.21181. Epub 2012 Jul 1.

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20.

Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.

Domínguez-Sánchez MS, Barroso S, Gómez-González B, Luna R, Aguilera A.

PLoS Genet. 2011 Dec;7(12):e1002386. doi: 10.1371/journal.pgen.1002386. Epub 2011 Dec 1.

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