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Items: 1 to 20 of 47

1.

Constitutive activity of human angiotensin II type-1 receptors by Gq overexpression.

Scragg JL, Warburton P, Ball SG, Balmforth AJ.

Biochem Biophys Res Commun. 2005 Aug 19;334(1):134-9.

PMID:
15992776
2.

Constitutive activity of endogenous receptors by inducible Gq overexpression.

Scragg JL, Ball SG, Balmforth AJ.

Biochem Biophys Res Commun. 2005 Jun 17;331(4):1239-44.

PMID:
15883008
3.

Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS.

Canals M, Jenkins L, Kellett E, Milligan G.

J Biol Chem. 2006 Jun 16;281(24):16757-67. Epub 2006 Apr 11.

4.

Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction.

Chanrion B, Mannoury la Cour C, Gavarini S, Seimandi M, Vincent L, Pujol JF, Bockaert J, Marin P, Millan MJ.

Mol Pharmacol. 2008 Mar;73(3):748-57. Epub 2007 Dec 14.

5.

Type 1 angiotensin receptor (AT1-R)-mediated decrease in type 2 angiotensin receptor mRNA level is dependent on Gq and extracellular signal-regulated kinase 1//2 in AT1-R-transfected PC12 cells.

Saito M, Shinohara Y, Sasaki H, Netsu Y, Yoshida M, Nakahata N.

J Neuroendocrinol. 2008 Mar;20(3):299-308. doi: 10.1111/j.1365-2826.2008.01646.x. Epub 2008 Jan 15.

PMID:
18208547
6.

Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists.

Christensen GL, Kelstrup CD, Lyngsø C, Sarwar U, Bøgebo R, Sheikh SP, Gammeltoft S, Olsen JV, Hansen JL.

Mol Cell Proteomics. 2010 Jul;9(7):1540-53. doi: 10.1074/mcp.M900550-MCP200. Epub 2010 Apr 2.

7.

Signaling through a G Protein-coupled receptor and its corresponding G protein follows a stoichiometrically limited model.

Philip F, Sengupta P, Scarlata S.

J Biol Chem. 2007 Jun 29;282(26):19203-16. Epub 2007 Apr 9.

8.

Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling.

Evanko DS, Thiyagarajan MM, Takida S, Wedegaertner PB.

Cell Signal. 2005 Oct;17(10):1218-28. Epub 2005 Jan 22.

PMID:
16038796
9.

AT(1) receptor Gαq protein-independent signalling transcriptionally activates only a few genes directly, but robustly potentiates gene regulation from the β2-adrenergic receptor.

Christensen GL, Knudsen S, Schneider M, Aplin M, Gammeltoft S, Sheikh SP, Hansen JL.

Mol Cell Endocrinol. 2011 Jan 1;331(1):49-56. doi: 10.1016/j.mce.2010.08.004. Epub 2010 Aug 12.

PMID:
20708651
10.

Angiotensin II type 1 and bradykinin B2 receptors expressed in early stage epithelial cells derived from human embryonic stem cells.

Huang Z, Yu J, Toselli P, Bhawan J, Sudireddy V, Taylor L, Polgar P.

J Cell Physiol. 2007 Jun;211(3):816-25.

PMID:
17299793
11.

Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors.

Seifert R, Wenzel-Seifert K.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Nov;366(5):381-416. Epub 2002 Sep 6. Review.

PMID:
12382069
12.

Ca2+ responses to thyrotropin-releasing hormone and angiotensin II: the role of plasma membrane integrity and effect of G11alpha protein overexpression on homologous and heterologous desensitization.

Ostasov P, Krusek J, Durchankova D, Svoboda P, Novotny J.

Cell Biochem Funct. 2008 Mar-Apr;26(2):264-74. Erratum in: Cell Biochem Funct. 2008 Mar-Apr;26(2). doi: 10.1002/cbf.1466.

PMID:
18041110
13.

High glucose increases the expression of Gq/11alpha and PLC-beta proteins and associated signaling in vascular smooth muscle cells.

Descorbeth M, Anand-Srivastava MB.

Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2135-42. doi: 10.1152/ajpheart.00704.2008. Epub 2008 Sep 26.

14.
16.

Comparative analysis of the human angiotensin II type 1a receptor heterologously produced in insect cells and mammalian cells.

Shukla AK, Reinhart C, Michel H.

Biochem Biophys Res Commun. 2006 Oct 13;349(1):6-14.

PMID:
16963356
17.

The constitutively active N111G-AT1 receptor for angiotensin II maintains a high affinity conformation despite being uncoupled from its cognate G protein Gq/11alpha.

Auger-Messier M, Clement M, Lanctot PM, Leclerc PC, Leduc R, Escher E, Guillemette G.

Endocrinology. 2003 Dec;144(12):5277-84. Epub 2003 Aug 13.

PMID:
12960024
18.

Agonist-induced tyrosine phosphorylation of Gq/G11 alpha requires the intact structure of membrane domains.

Matousek P, Durchánková D, Svandová I, Novotny J, Svoboda P.

Biochem Biophys Res Commun. 2005 Mar 11;328(2):526-32.

PMID:
15694379
19.

Altered expression of G(q/11alpha) protein shapes mGlu1 and mGlu5 receptor-mediated single cell inositol 1,4,5-trisphosphate and Ca(2+) signaling.

Atkinson PJ, Young KW, Ennion SJ, Kew JN, Nahorski SR, Challiss RA.

Mol Pharmacol. 2006 Jan;69(1):174-84. Epub 2005 Oct 18.

20.

Angiotensin II AT1 receptor constitutive activation: from molecular mechanisms to pathophysiology.

Petrel C, Clauser E.

Mol Cell Endocrinol. 2009 Apr 29;302(2):176-84. doi: 10.1016/j.mce.2008.10.049. Epub 2008 Nov 17.

PMID:
19061936

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