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Items: 1 to 20 of 151


Na/K-ATPase tethers phospholipase C and IP3 receptor into a calcium-regulatory complex.

Yuan Z, Cai T, Tian J, Ivanov AV, Giovannucci DR, Xie Z.

Mol Biol Cell. 2005 Sep;16(9):4034-45. Epub 2005 Jun 22.


Ouabain assembles signaling cascades through the caveolar Na+/K+-ATPase.

Wang H, Haas M, Liang M, Cai T, Tian J, Li S, Xie Z.

J Biol Chem. 2004 Apr 23;279(17):17250-9. Epub 2004 Feb 12.


Cell signaling microdomain with Na,K-ATPase and inositol 1,4,5-trisphosphate receptor generates calcium oscillations.

Miyakawa-Naito A, Uhlén P, Lal M, Aizman O, Mikoshiba K, Brismar H, Zelenin S, Aperia A.

J Biol Chem. 2003 Dec 12;278(50):50355-61. Epub 2003 Aug 28.


Ouabain-induced endocytosis of the plasmalemmal Na/K-ATPase in LLC-PK1 cells requires caveolin-1.

Liu J, Liang M, Liu L, Malhotra D, Xie Z, Shapiro JI.

Kidney Int. 2005 May;67(5):1844-54.


Binding of Src to Na+/K+-ATPase forms a functional signaling complex.

Tian J, Cai T, Yuan Z, Wang H, Liu L, Haas M, Maksimova E, Huang XY, Xie ZJ.

Mol Biol Cell. 2006 Jan;17(1):317-26. Epub 2005 Nov 2.


Functional characterization of Src-interacting Na/K-ATPase using RNA interference assay.

Liang M, Cai T, Tian J, Qu W, Xie ZJ.

J Biol Chem. 2006 Jul 14;281(28):19709-19. Epub 2006 May 12.


Regulation of inositol 1,4,5-trisphosphate receptor-mediated calcium release by the Na/K-ATPase in cultured renal epithelial cells.

Chen Y, Cai T, Yang C, Turner DA, Giovannucci DR, Xie Z.

J Biol Chem. 2008 Jan 11;283(2):1128-36. Epub 2007 Nov 9.


Role of caveolae in signal-transducing function of cardiac Na+/K+-ATPase.

Liu L, Mohammadi K, Aynafshar B, Wang H, Li D, Liu J, Ivanov AV, Xie Z, Askari A.

Am J Physiol Cell Physiol. 2003 Jun;284(6):C1550-60. Epub 2003 Feb 26.


Ammonia-induced Na,K-ATPase/ouabain-mediated EGF receptor transactivation, MAPK/ERK and PI3K/AKT signaling and ROS formation cause astrocyte swelling.

Dai H, Song D, Xu J, Li B, Hertz L, Peng L.

Neurochem Int. 2013 Nov;63(6):610-25. doi: 10.1016/j.neuint.2013.09.005. Epub 2013 Sep 14.


Expression of rat Na-K-ATPase α2 enables ion pumping but not ouabain-induced signaling in α1-deficient porcine renal epithelial cells.

Xie J, Ye Q, Cui X, Madan N, Yi Q, Pierre SV, Xie Z.

Am J Physiol Cell Physiol. 2015 Sep 15;309(6):C373-82. doi: 10.1152/ajpcell.00103.2015. Epub 2015 Jun 24.


Ouabain induces endocytosis of plasmalemmal Na/K-ATPase in LLC-PK1 cells by a clathrin-dependent mechanism.

Liu J, Kesiry R, Periyasamy SM, Malhotra D, Xie Z, Shapiro JI.

Kidney Int. 2004 Jul;66(1):227-41.


Ouabain modulation of cellular calcium stores and signaling.

Edwards A, Pallone TL.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1518-32. Epub 2007 Aug 1.


Distinct role of the N-terminal tail of the Na,K-ATPase catalytic subunit as a signal transducer.

Zhang S, Malmersjö S, Li J, Ando H, Aizman O, Uhlén P, Mikoshiba K, Aperia A.

J Biol Chem. 2006 Aug 4;281(31):21954-62. Epub 2006 May 24.


Involvement of Na/K-ATPase in hydrogen peroxide-induced activation of the Src/ERK pathway in LLC-PK1 cells.

Wang Y, Ye Q, Liu C, Xie JX, Yan Y, Lai F, Duan Q, Li X, Tian J, Xie Z.

Free Radic Biol Med. 2014 Jun;71:415-26. doi: 10.1016/j.freeradbiomed.2014.03.036. Epub 2014 Apr 1.


Changes in sodium pump expression dictate the effects of ouabain on cell growth.

Tian J, Li X, Liang M, Liu L, Xie JX, Ye Q, Kometiani P, Tillekeratne M, Jin R, Xie Z.

J Biol Chem. 2009 May 29;284(22):14921-9. doi: 10.1074/jbc.M808355200. Epub 2009 Mar 27.


NaKtide, a Na/K-ATPase-derived peptide Src inhibitor, antagonizes ouabain-activated signal transduction in cultured cells.

Li Z, Cai T, Tian J, Xie JX, Zhao X, Liu L, Shapiro JI, Xie Z.

J Biol Chem. 2009 Jul 31;284(31):21066-76. doi: 10.1074/jbc.M109.013821. Epub 2009 Jun 8.


Role of protein kinase C in the signal pathways that link Na+/K+-ATPase to ERK1/2.

Mohammadi K, Kometiani P, Xie Z, Askari A.

J Biol Chem. 2001 Nov 9;276(45):42050-6. Epub 2001 Sep 18.


Do Src Kinase and Caveolin Interact Directly with Na,K-ATPase?

Yosef E, Katz A, Peleg Y, Mehlman T, Karlish SJ.

J Biol Chem. 2016 May 27;291(22):11736-50. doi: 10.1074/jbc.M116.721084. Epub 2016 Mar 28.


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