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Items: 1 to 20 of 235


TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing.

Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R.

Nature. 2005 Aug 4;436(7051):740-4.


The role of PACT in the RNA silencing pathway.

Lee Y, Hur I, Park SY, Kim YK, Suh MR, Kim VN.

EMBO J. 2006 Feb 8;25(3):522-32.


A human, ATP-independent, RISC assembly machine fueled by pre-miRNA.

Maniataki E, Mourelatos Z.

Genes Dev. 2005 Dec 15;19(24):2979-90.


Structural insights into RNA processing by the human RISC-loading complex.

Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E.

Nat Struct Mol Biol. 2009 Nov;16(11):1148-53. doi: 10.1038/nsmb.1673.


Clarifying mammalian RISC assembly in vitro.

Tan GS, Garchow BG, Liu X, Metzler D, Kiriakidou M.

BMC Mol Biol. 2011 Apr 29;12:19. doi: 10.1186/1471-2199-12-19.


Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing.

Lee HY, Zhou K, Smith AM, Noland CL, Doudna JA.

Nucleic Acids Res. 2013 Jul;41(13):6568-76. doi: 10.1093/nar/gkt361.


Multiple sensors ensure guide strand selection in human RNAi pathways.

Noland CL, Doudna JA.

RNA. 2013 May;19(5):639-48. doi: 10.1261/rna.037424.112.


Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.

Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R.

Cell. 2005 Nov 18;123(4):631-40.


TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing.

Haase AD, Jaskiewicz L, Zhang H, Lainé S, Sack R, Gatignol A, Filipowicz W.

EMBO Rep. 2005 Oct;6(10):961-7.


Purification and assembly of human Argonaute, Dicer, and TRBP complexes.

De N, Macrae IJ.

Methods Mol Biol. 2011;725:107-19. doi: 10.1007/978-1-61779-046-1_8.


In vitro reconstitution of the human RISC-loading complex.

MacRae IJ, Ma E, Zhou M, Robinson CV, Doudna JA.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):512-7. doi: 10.1073/pnas.0710869105.


The role of Dicer protein partners in the processing of microRNA precursors.

Koscianska E, Starega-Roslan J, Krzyzosiak WJ.

PLoS One. 2011;6(12):e28548. doi: 10.1371/journal.pone.0028548.


The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domains.

Benoit MP, Imbert L, Palencia A, Pérard J, Ebel C, Boisbouvier J, Plevin MJ.

Nucleic Acids Res. 2013 Apr;41(7):4241-52. doi: 10.1093/nar/gkt086.


Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis.

Wilson RC, Tambe A, Kidwell MA, Noland CL, Schneider CP, Doudna JA.

Mol Cell. 2015 Feb 5;57(3):397-407. doi: 10.1016/j.molcel.2014.11.030.


Identification of novel argonaute-associated proteins.

Meister G, Landthaler M, Peters L, Chen PY, Urlaub H, Lührmann R, Tuschl T.

Curr Biol. 2005 Dec 6;15(23):2149-55.


Expanded RNA-binding activities of mammalian Argonaute 2.

Tan GS, Garchow BG, Liu X, Yeung J, Morris JP 4th, Cuellar TL, McManus MT, Kiriakidou M.

Nucleic Acids Res. 2009 Dec;37(22):7533-45. doi: 10.1093/nar/gkp812.


DICER-ARGONAUTE2 complex in continuous fluorogenic assays of RNA interference enzymes.

Bernard MA, Wang L, Tachado SD.

PLoS One. 2015 Mar 20;10(3):e0120614. doi: 10.1371/journal.pone.0120614.


Intracellular localization and routing of miRNA and RNAi pathway components.

Ohrt T, Muetze J, Svoboda P, Schwille P.

Curr Top Med Chem. 2012;12(2):79-88. Review.

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