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Items: 1 to 20 of 300

1.

Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim.

Möller C, Alfredsson J, Engström M, Wootz H, Xiang Z, Lennartsson J, Jönsson JI, Nilsson G.

Blood. 2005 Aug 15;106(4):1330-6.

2.

FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells.

Shukla S, Rizvi F, Raisuddin S, Kakkar P.

Free Radic Biol Med. 2014 Nov;76:185-99. doi: 10.1016/j.freeradbiomed.2014.07.039.

PMID:
25128467
3.

Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons.

Linseman DA, Phelps RA, Bouchard RJ, Le SS, Laessig TA, McClure ML, Heidenreich KA.

J Neurosci. 2002 Nov 1;22(21):9287-97.

4.

Melatonin induces transcriptional regulation of Bim by FoxO3a in HepG2 cells.

Carbajo-Pescador S, Steinmetz C, Kashyap A, Lorenz S, Mauriz JL, Heise M, Galle PR, González-Gallego J, Strand S.

Br J Cancer. 2013 Feb 5;108(2):442-9. doi: 10.1038/bjc.2012.563.

5.

The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells.

Ekoff M, Kaufmann T, Engström M, Motoyama N, Villunger A, Jönsson JI, Strasser A, Nilsson G.

Blood. 2007 Nov 1;110(9):3209-17.

6.

BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3.

Nordigården A, Kraft M, Eliasson P, Labi V, Lam EW, Villunger A, Jönsson JI.

Blood. 2009 Mar 5;113(10):2302-11. doi: 10.1182/blood-2008-07-167023.

7.
8.

Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim.

Zhang W, Konopleva M, Burks JK, Dywer KC, Schober WD, Yang JY, McQueen TJ, Hung MC, Andreeff M.

Cancer Res. 2010 Mar 15;70(6):2424-34. doi: 10.1158/0008-5472.CAN-09-0878.

9.

Follicle-stimulating hormone regulates pro-apoptotic protein Bcl-2-interacting mediator of cell death-extra long (BimEL)-induced porcine granulosa cell apoptosis.

Wang XL, Wu Y, Tan LB, Tian Z, Liu JH, Zhu DS, Zeng SM.

J Biol Chem. 2012 Mar 23;287(13):10166-77. doi: 10.1074/jbc.M111.293274.

10.

Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim.

Meng J, Fang B, Liao Y, Chresta CM, Smith PD, Roth JA.

PLoS One. 2010 Sep 27;5(9):e13026. doi: 10.1371/journal.pone.0013026.

11.

IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms.

De Bruyne E, Bos TJ, Schuit F, Van Valckenborgh E, Menu E, Thorrez L, Atadja P, Jernberg-Wiklund H, Vanderkerken K.

Blood. 2010 Mar 25;115(12):2430-40. doi: 10.1182/blood-2009-07-232801.

12.

RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells.

Yamamura Y, Lee WL, Inoue K, Ida H, Ito Y.

J Biol Chem. 2006 Feb 24;281(8):5267-76.

13.

Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells.

Guan H, Song L, Cai J, Huang Y, Wu J, Yuan J, Li J, Li M.

PLoS One. 2011;6(5):e19946. doi: 10.1371/journal.pone.0019946.

14.

Involvement of the JNK/FOXO3a/Bim Pathway in Neuronal Apoptosis after Hypoxic-Ischemic Brain Damage in Neonatal Rats.

Li D, Li X, Wu J, Li J, Zhang L, Xiong T, Tang J, Qu Y, Mu D.

PLoS One. 2015 Jul 14;10(7):e0132998. doi: 10.1371/journal.pone.0132998.

15.

Involvement of the PTEN-AKT-FOXO3a pathway in neuronal apoptosis in developing rat brain after hypoxia-ischemia.

Li D, Qu Y, Mao M, Zhang X, Li J, Ferriero D, Mu D.

J Cereb Blood Flow Metab. 2009 Dec;29(12):1903-13. doi: 10.1038/jcbfm.2009.102.

16.

18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells.

Sharma G, Kar S, Palit S, Das PK.

J Cell Physiol. 2012 May;227(5):1923-31. doi: 10.1002/jcp.22920.

PMID:
21732363
17.

Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis.

Barreyro FJ, Kobayashi S, Bronk SF, Werneburg NW, Malhi H, Gores GJ.

J Biol Chem. 2007 Sep 14;282(37):27141-54.

18.
19.

Regulation of FOXO3a by brain-derived neurotrophic factor in differentiated human SH-SY5Y neuroblastoma cells.

Zhu W, Bijur GN, Styles NA, Li X.

Brain Res Mol Brain Res. 2004 Jul 5;126(1):45-56.

PMID:
15207915
20.

Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.

Huntington ND, Puthalakath H, Gunn P, Naik E, Michalak EM, Smyth MJ, Tabarias H, Degli-Esposti MA, Dewson G, Willis SN, Motoyama N, Huang DC, Nutt SL, Tarlinton DM, Strasser A.

Nat Immunol. 2007 Aug;8(8):856-63.

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