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Items: 1 to 20 of 450

1.

Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells.

Itoh S, Lemay S, Osawa M, Che W, Duan Y, Tompkins A, Brookes PS, Sheu SS, Abe J.

J Biol Chem. 2005 Jul 15;280(28):26383-96. Epub 2005 Apr 26.

2.
4.

Src kinase activity is required for integrin alphaVbeta3-mediated activation of nuclear factor-kappaB.

Courter DL, Lomas L, Scatena M, Giachelli CM.

J Biol Chem. 2005 Apr 1;280(13):12145-51. Epub 2005 Jan 28.

5.

Reactive oxygen species are downstream products of TRAF-mediated signal transduction.

Chandel NS, Schumacker PT, Arch RH.

J Biol Chem. 2001 Nov 16;276(46):42728-36. Epub 2001 Sep 14.

6.
7.

GIT1 is a scaffold for ERK1/2 activation in focal adhesions.

Yin G, Zheng Q, Yan C, Berk BC.

J Biol Chem. 2005 Jul 29;280(30):27705-12. Epub 2005 May 27.

8.

A novel dominant-negative mutant form of Epstein-Barr virus latent membrane protein-1 (LMP1) selectively and differentially impairs LMP1 and TNF signaling pathways.

Adriaenssens E, Mougel A, Goormachtigh G, Loing E, Fafeur V, Auriault C, Coll J.

Oncogene. 2004 Apr 8;23(15):2681-93. Erratum in: Oncogene. 2004 Oct 21;23(49):8184.

PMID:
14767477
9.

Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells.

Wang Q, Pfeiffer GR 2nd, Gaarde WA.

J Biol Chem. 2003 Nov 28;278(48):47731-43. Epub 2003 Sep 22.

10.

PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit.

Jang HD, Yoon K, Shin YJ, Kim J, Lee SY.

J Biol Chem. 2004 Jun 4;279(23):24873-80. Epub 2004 Mar 26.

11.

Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production.

Ferlito M, Romanenko OG, Guyton K, Ashton S, Squadrito F, Halushka PV, Cook JA.

J Endotoxin Res. 2002;8(6):427-35.

PMID:
12701623
12.

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression.

Che W, Lerner-Marmarosh N, Huang Q, Osawa M, Ohta S, Yoshizumi M, Glassman M, Lee JD, Yan C, Berk BC, Abe J.

Circ Res. 2002 Jun 14;90(11):1222-30.

13.

Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase.

Uchida M, Enomoto A, Fukuda T, Kurokawa K, Maeda K, Kodama Y, Asai N, Hasegawa T, Shimono Y, Jijiwa M, Ichihara M, Murakumo Y, Takahashi M.

J Cell Sci. 2006 Aug 1;119(Pt 15):3067-77. Epub 2006 Jul 4.

14.

Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization.

Master Z, Tran J, Bishnoi A, Chen SH, Ebos JM, Van Slyke P, Kerbel RS, Dumont DJ.

J Biol Chem. 2003 Aug 8;278(32):30170-9. Epub 2003 May 30.

16.

Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway.

Yeh M, Gharavi NM, Choi J, Hsieh X, Reed E, Mouillesseaux KP, Cole AL, Reddy ST, Berliner JA.

J Biol Chem. 2004 Jul 16;279(29):30175-81. Epub 2004 May 13.

18.

Inhibition of tumor necrosis factor-[alpha]-induced SHP-2 phosphatase activity by shear stress: a mechanism to reduce endothelial inflammation.

Lerner-Marmarosh N, Yoshizumi M, Che W, Surapisitchat J, Kawakatsu H, Akaike M, Ding B, Huang Q, Yan C, Berk BC, Abe J.

Arterioscler Thromb Vasc Biol. 2003 Oct 1;23(10):1775-81. Epub 2003 Aug 28.

19.

The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation.

Huang Q, Lerner-Marmarosh N, Che W, Ohta S, Osawa M, Yoshizumi M, Glassman M, Yan C, Berk BC, Abe J.

J Biol Chem. 2002 Aug 9;277(32):29330-41. Epub 2002 May 14. Erratum in: J Biol Chem. 2003 May 23;278(21):19574.

20.

TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells.

Lee CW, Lin CC, Lin WN, Liang KC, Luo SF, Wu CB, Wang SW, Yang CM.

Am J Physiol Lung Cell Mol Physiol. 2007 Mar;292(3):L799-812. Epub 2006 Dec 8.

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