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Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation.

Kubota K, Lee DH, Tsuchiya M, Young CS, Everett ET, Martinez-Mier EA, Snead ML, Nguyen L, Urano F, Bartlett JD.

J Biol Chem. 2005 Jun 17;280(24):23194-202. Epub 2005 Apr 23.


Sirtuin1 and autophagy protect cells from fluoride-induced cell stress.

Suzuki M, Bartlett JD.

Biochim Biophys Acta. 2014 Feb;1842(2):245-55. doi: 10.1016/j.bbadis.2013.11.023. Epub 2013 Dec 1.


Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro.

Sun S, Han J, Ralph WM Jr, Chandrasekaran A, Liu K, Auborn KJ, Carter TH.

Cell Stress Chaperones. 2004 Mar;9(1):76-87.


Geranylgeranylacetone, an inducer of the 70-kDa heat shock protein (HSP70), elicits unfolded protein response and coordinates cellular fate independently of HSP70.

Endo S, Hiramatsu N, Hayakawa K, Okamura M, Kasai A, Tagawa Y, Sawada N, Yao J, Kitamura M.

Mol Pharmacol. 2007 Nov;72(5):1337-48. Epub 2007 Aug 16.


Fluoride induced endoplasmic reticulum stress and calcium overload in ameloblasts.

Zhang Y, Zhang K, Ma L, Gu H, Li J, Lei S.

Arch Oral Biol. 2016 Sep;69:95-101. doi: 10.1016/j.archoralbio.2016.05.015. Epub 2016 May 26.


Endoplasmic reticulum stress-mediated apoptotic pathway is involved in corpus luteum regression in rats.

Yang Y, Sun M, Shan Y, Zheng X, Ma H, Ma W, Wang Z, Pei X, Wang Y.

Reprod Sci. 2015 May;22(5):572-84. doi: 10.1177/1933719114553445. Epub 2014 Oct 20.


Fluoride induces oxidative damage and SIRT1/autophagy through ROS-mediated JNK signaling.

Suzuki M, Bandoski C, Bartlett JD.

Free Radic Biol Med. 2015 Dec;89:369-78. doi: 10.1016/j.freeradbiomed.2015.08.015. Epub 2015 Sep 30.


A cellular UDP-glucose deficiency causes overexpression of glucose/oxygen-regulated proteins independent of the endoplasmic reticulum stress elements.

Flores-Diaz M, Higuita JC, Florin I, Okada T, Pollesello P, Bergman T, Thelestam M, Mori K, Alape-Giron A.

J Biol Chem. 2004 May 21;279(21):21724-31. Epub 2004 Mar 12.


Fluoride induces endoplasmic reticulum stress and inhibits protein synthesis and secretion.

Sharma R, Tsuchiya M, Bartlett JD.

Environ Health Perspect. 2008 Sep;116(9):1142-6. doi: 10.1289/ehp.11375.


Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.

Lipson KL, Fonseca SG, Ishigaki S, Nguyen LX, Foss E, Bortell R, Rossini AA, Urano F.

Cell Metab. 2006 Sep;4(3):245-54.


Fluorosis induces endoplasmic reticulum stress and apoptosis in osteoblasts in vivo.

Liu L, Zhang Y, Gu H, Zhang K, Ma L.

Biol Trace Elem Res. 2015 Mar;164(1):64-71. doi: 10.1007/s12011-014-0192-4. Epub 2014 Dec 2.


Excessive fluoride induces endoplasmic reticulum stress and interferes enamel proteinases secretion.

Wei W, Gao Y, Wang C, Zhao L, Sun D.

Environ Toxicol. 2013 Jun;28(6):332-41. doi: 10.1002/tox.20724. Epub 2011 May 27.


La3+ binds to BiP/GRP78 and induces unfolded protein response in HepG2 cells.

Shen C, Li Z, Yang X, Wang K.

Chem Biol Interact. 2008 Nov 25;176(2-3):196-203. doi: 10.1016/j.cbi.2008.07.014. Epub 2008 Aug 19.


Quantitative measurement of spliced XBP1 mRNA as an indicator of endoplasmic reticulum stress.

Hirota M, Kitagaki M, Itagaki H, Aiba S.

J Toxicol Sci. 2006 May;31(2):149-56.


Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway.

Shi K, Wang D, Cao X, Ge Y.

PLoS One. 2013;8(3):e59330. doi: 10.1371/journal.pone.0059330. Epub 2013 Mar 22.


Aberrant accumulation of fibulin-3 in the endoplasmic reticulum leads to activation of the unfolded protein response and VEGF expression.

Roybal CN, Marmorstein LY, Vander Jagt DL, Abcouwer SF.

Invest Ophthalmol Vis Sci. 2005 Nov;46(11):3973-9.


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