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Items: 1 to 20 of 95

1.

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.

Rother RP, Bell L, Hillmen P, Gladwin MT.

JAMA. 2005 Apr 6;293(13):1653-62. Review.

PMID:
15811985
2.

[Pathophysiological consequences of hemolysis. Role of cell-free hemoglobin].

Misztal T, Tomasiak M.

Postepy Hig Med Dosw (Online). 2011 Sep 28;65:627-39. Review. Polish.

3.

The biochemistry of nitric oxide, nitrite, and hemoglobin: role in blood flow regulation.

Gladwin MT, Crawford JH, Patel RP.

Free Radic Biol Med. 2004 Mar 15;36(6):707-17. Review.

PMID:
14990351
4.

Role of the red blood cell in nitric oxide homeostasis and hypoxic vasodilation.

Gladwin MT.

Adv Exp Med Biol. 2006;588:189-205. Review.

PMID:
17089890
5.

Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin.

Villagra J, Shiva S, Hunter LA, Machado RF, Gladwin MT, Kato GJ.

Blood. 2007 Sep 15;110(6):2166-72. Epub 2007 May 29.

6.

Sickle cell disease vasculopathy: a state of nitric oxide resistance.

Wood KC, Hsu LL, Gladwin MT.

Free Radic Biol Med. 2008 Apr 15;44(8):1506-28. doi: 10.1016/j.freeradbiomed.2008.01.008. Epub 2008 Jan 26. Review.

PMID:
18261470
7.

Computation of plasma hemoglobin nitric oxide scavenging in hemolytic anemias.

Jeffers A, Gladwin MT, Kim-Shapiro DB.

Free Radic Biol Med. 2006 Nov 15;41(10):1557-65. Epub 2006 Aug 25.

8.

Sickle cell anemia and vascular dysfunction: the nitric oxide connection.

Akinsheye I, Klings ES.

J Cell Physiol. 2010 Sep;224(3):620-5. doi: 10.1002/jcp.22195. Review.

PMID:
20578237
9.

Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin.

Minneci PC, Deans KJ, Zhi H, Yuen PS, Star RA, Banks SM, Schechter AN, Natanson C, Gladwin MT, Solomon SB.

J Clin Invest. 2005 Dec;115(12):3409-17. Epub 2005 Nov 17.

10.

Vasculopathy and pulmonary hypertension in sickle cell disease.

Potoka KP, Gladwin MT.

Am J Physiol Lung Cell Mol Physiol. 2015 Feb 15;308(4):L314-24. doi: 10.1152/ajplung.00252.2014. Epub 2014 Nov 14. Review.

11.

Mechanisms of hemolysis-associated platelet activation.

Helms CC, Marvel M, Zhao W, Stahle M, Vest R, Kato GJ, Lee JS, Christ G, Gladwin MT, Hantgan RR, Kim-Shapiro DB.

J Thromb Haemost. 2013 Dec;11(12):2148-54. doi: 10.1111/jth.12422.

12.

A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia.

Hanson MS, Xu H, Flewelen TC, Holzhauer SL, Retherford D, Jones DW, Frei AC, Pritchard KA Jr, Hillery CA, Hogg N, Wandersee NJ.

Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H328-36. doi: 10.1152/ajpheart.00500.2012. Epub 2012 Nov 2.

13.

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.

Hsu LL, Champion HC, Campbell-Lee SA, Bivalacqua TJ, Manci EA, Diwan BA, Schimel DM, Cochard AE, Wang X, Schechter AN, Noguchi CT, Gladwin MT.

Blood. 2007 Apr 1;109(7):3088-98. Erratum in: Blood. 2008 Feb 15;111(4):1772.

14.

Low micromolar intravascular cell-free hemoglobin concentration affects vascular NO bioavailability in sickle cell disease: a computational analysis.

Deonikar P, Kavdia M.

J Appl Physiol (1985). 2012 Apr;112(8):1383-92. doi: 10.1152/japplphysiol.01173.2011. Epub 2012 Jan 5.

15.

Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion.

Donadee C, Raat NJ, Kanias T, Tejero J, Lee JS, Kelley EE, Zhao X, Liu C, Reynolds H, Azarov I, Frizzell S, Meyer EM, Donnenberg AD, Qu L, Triulzi D, Kim-Shapiro DB, Gladwin MT.

Circulation. 2011 Jul 26;124(4):465-76. doi: 10.1161/CIRCULATIONAHA.110.008698. Epub 2011 Jul 11.

16.

New insights into paroxysmal nocturnal hemoglobinuria.

Savage WJ, Brodsky RA.

Hematology. 2007 Oct;12(5):371-6. Review.

PMID:
17852463
17.

Cardiopulmonary complications of sickle cell disease: role of nitric oxide and hemolytic anemia.

Gladwin MT, Kato GJ.

Hematology Am Soc Hematol Educ Program. 2005:51-7.

18.

Hemoglobin interaction with GP1bα induces platelet activation and apoptosis: a novel mechanism associated with intravascular hemolysis.

Singhal R, Annarapu GK, Pandey A, Chawla S, Ojha A, Gupta A, Cruz MA, Seth T, Guchhait P.

Haematologica. 2015 Dec;100(12):1526-33. doi: 10.3324/haematol.2015.132183. Epub 2015 Sep 4.

19.

The potential of Angeli's salt to decrease nitric oxide scavenging by plasma hemoglobin.

He X, Azarov I, Jeffers A, Presley T, Richardson J, King SB, Gladwin MT, Kim-Shapiro DB.

Free Radic Biol Med. 2008 Apr 1;44(7):1420-32. doi: 10.1016/j.freeradbiomed.2007.12.038. Epub 2008 Jan 11.

20.

Intravascular hemolysis and the pathophysiology of sickle cell disease.

Kato GJ, Steinberg MH, Gladwin MT.

J Clin Invest. 2017 Mar 1;127(3):750-760. doi: 10.1172/JCI89741. Epub 2017 Mar 1. Review.

PMID:
28248201

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