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Items: 1 to 20 of 199

1.

Gli1 is important for medulloblastoma formation in Ptc1+/- mice.

Kimura H, Stephen D, Joyner A, Curran T.

Oncogene. 2005 Jun 9;24(25):4026-36.

PMID:
15806168
2.
3.

A mouse model for medulloblastoma and basal cell nevus syndrome.

Corcoran RB, Scott MP.

J Neurooncol. 2001 Jul;53(3):307-18. Review.

PMID:
11718263
4.

Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.

Lipinski RJ, Gipp JJ, Zhang J, Doles JD, Bushman W.

Exp Cell Res. 2006 Jul 1;312(11):1925-38.

PMID:
16571352
5.

Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures.

Cohen JR, Resnick DZ, Niewiadomski P, Dong H, Liau LM, Waschek JA.

BMC Cancer. 2010 Dec 9;10:676. doi: 10.1186/1471-2407-10-676.

6.

Altered neural cell fates and medulloblastoma in mouse patched mutants.

Goodrich LV, Milenković L, Higgins KM, Scott MP.

Science. 1997 Aug 22;277(5329):1109-13.

7.

Evidence that haploinsufficiency of Ptch leads to medulloblastoma in mice.

Zurawel RH, Allen C, Wechsler-Reya R, Scott MP, Raffel C.

Genes Chromosomes Cancer. 2000 May;28(1):77-81.

PMID:
10738305
8.

Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor.

Sasai K, Romer JT, Kimura H, Eberhart DE, Rice DS, Curran T.

Cancer Res. 2007 Apr 15;67(8):3871-7.

9.

Several PATCHED1 missense mutations display activity in patched1-deficient fibroblasts.

Bailey EC, Milenkovic L, Scott MP, Collawn JF, Johnson RL.

J Biol Chem. 2002 Sep 13;277(37):33632-40.

10.

Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma.

Ayrault O, Zindy F, Rehg J, Sherr CJ, Roussel MF.

Mol Cancer Res. 2009 Jan;7(1):33-40. doi: 10.1158/1541-7786.MCR-08-0369.

11.

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.

Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL.

Development. 2000 Apr;127(8):1593-605.

12.

Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.

Shahi MH, Afzal M, Sinha S, Eberhart CG, Rey JA, Fan X, Castresana JS.

BMC Cancer. 2010 Nov 8;10:614. doi: 10.1186/1471-2407-10-614.

13.

Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.

Agren M, Kogerman P, Kleman MI, Wessling M, Toftgård R.

Gene. 2004 Apr 14;330:101-14.

PMID:
15087129
14.

The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants.

Hardcastle Z, Mo R, Hui CC, Sharpe PT.

Development. 1998 Aug;125(15):2803-11.

15.

GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis.

Hu MC, Mo R, Bhella S, Wilson CW, Chuang PT, Hui CC, Rosenblum ND.

Development. 2006 Feb;133(3):569-78.

16.

Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes.

Yoon JW, Gilbertson R, Iannaccone S, Iannaccone P, Walterhouse D.

Int J Cancer. 2009 Jan 1;124(1):109-19. doi: 10.1002/ijc.23929.

17.

Gli function is essential for motor neuron induction in zebrafish.

Vanderlaan G, Tyurina OV, Karlstrom RO, Chandrasekhar A.

Dev Biol. 2005 Jun 15;282(2):550-70.

18.

Sonic Hedgehog signaling impairs ionizing radiation-induced checkpoint activation and induces genomic instability.

Leonard JM, Ye H, Wetmore C, Karnitz LM.

J Cell Biol. 2008 Nov 3;183(3):385-91. doi: 10.1083/jcb.200804042.

19.

Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1.

Weiner HL, Bakst R, Hurlbert MS, Ruggiero J, Ahn E, Lee WS, Stephen D, Zagzag D, Joyner AL, Turnbull DH.

Cancer Res. 2002 Nov 15;62(22):6385-9.

20.

Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice.

Pazzaglia S, Tanori M, Mancuso M, Gessi M, Pasquali E, Leonardi S, Oliva MA, Rebessi S, Di Majo V, Covelli V, Giangaspero F, Saran A.

Oncogene. 2006 Sep 7;25(40):5575-80.

PMID:
16636673

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