Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 87


Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling.

Chavez JA, Holland WL, Bär J, Sandhoff K, Summers SA.

J Biol Chem. 2005 May 20;280(20):20148-53. Epub 2005 Mar 17.


A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids.

Chavez JA, Knotts TA, Wang LP, Li G, Dobrowsky RT, Florant GL, Summers SA.

J Biol Chem. 2003 Mar 21;278(12):10297-303. Epub 2003 Jan 13.


Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

Stratford S, Hoehn KL, Liu F, Summers SA.

J Biol Chem. 2004 Aug 27;279(35):36608-15. Epub 2004 Jun 25.


Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

Summers SA, Garza LA, Zhou H, Birnbaum MJ.

Mol Cell Biol. 1998 Sep;18(9):5457-64.


Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells.

Deng YT, Chang TW, Lee MS, Lin JK.

J Agric Food Chem. 2012 Feb 1;60(4):1059-66. doi: 10.1021/jf204496f. Epub 2012 Jan 17.


Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.

Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A, Tsujimoto G.

J Biol Chem. 2005 May 20;280(20):19507-15. Epub 2005 Mar 17.


Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells.

Hirabara SM, Curi R, Maechler P.

J Cell Physiol. 2010 Jan;222(1):187-94. doi: 10.1002/jcp.21936.


Modulation of cellular insulin signaling and PTP1B effects by lipid metabolites in skeletal muscle cells.

Obanda DN, Cefalu WT.

J Nutr Biochem. 2013 Aug;24(8):1529-37. doi: 10.1016/j.jnutbio.2012.12.014. Epub 2013 Mar 6.


Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B.

Sinha S, Perdomo G, Brown NF, O'Doherty RM.

J Biol Chem. 2004 Oct 1;279(40):41294-301. Epub 2004 Jul 12.


Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB.

Weigert C, Brodbeck K, Staiger H, Kausch C, Machicao F, Häring HU, Schleicher ED.

J Biol Chem. 2004 Jun 4;279(23):23942-52. Epub 2004 Mar 17.


Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes.

Kadotani A, Tsuchiya Y, Hatakeyama H, Katagiri H, Kanzaki M.

Am J Physiol Endocrinol Metab. 2009 Dec;297(6):E1291-303. doi: 10.1152/ajpendo.00293.2009. Epub 2009 Sep 15.


Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid.

Sabin MA, Stewart CE, Crowne EC, Turner SJ, Hunt LP, Welsh GI, Grohmann MJ, Holly JM, Shield JP.

J Cell Physiol. 2007 Apr;211(1):244-52.


Effect of high fat diet enriched with unsaturated and diet rich in saturated fatty acids on sphingolipid metabolism in rat skeletal muscle.

Blachnio-Zabielska A, Baranowski M, Zabielski P, Gorski J.

J Cell Physiol. 2010 Nov;225(3):786-91. doi: 10.1002/jcp.22283.


Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress.

Yuzefovych L, Wilson G, Rachek L.

Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E1096-105. doi: 10.1152/ajpendo.00238.2010. Epub 2010 Sep 28.


JNK deficiency enhances fatty acid utilization and diverts glucose from oxidation to glycogen storage in cultured myotubes.

Vijayvargia R, Mann K, Weiss HR, Pownall HJ, Ruan H.

Obesity (Silver Spring). 2010 Sep;18(9):1701-9. doi: 10.1038/oby.2009.501. Epub 2010 Jan 21.

Supplemental Content

Support Center